- Mast Cells and Lipid Mediators
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Cho KA
- KMID: 2168743
- J Bacteriol Virol.
- 2016 Mar;46(1):47-51.
- doi: 10.4167/jbv.2016.46.1.47
Human mast cells are potent effector cells in host defense mechanisms of innate and acquired immunity, including inflammatory diseases such as asthma and atherosclerosis. Mast cells originate from pluripotent hematopoietic... -
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- Epoxyeicosatrienoic acid activation moderates endothelial mesenchymal transition to reduce obstructive nephropathy
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Padanilam
- KMID: 2405104
- Kidney Res Clin Pract.
- 2017 Dec;36(4):299-301.
- doi: 10.23876/j.krcp.2017.36.4.299
No abstract available. -
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- Eicosanoid Mediators in the Airway Inflammation of Asthmatic Patients: What is New?
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Sanak M
- KMID: 2349987
- Allergy Asthma Immunol Res.
- 2016 Nov;8(6):481-490.
- doi: 10.4168/aair.2016.8.6.481
Lipid mediators contribute to inflammation providing both pro-inflammatory signals and terminating the inflammatory process by activation of macrophages. Among the most significant biologically lipid mediators, these are produced by free-radical... -
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- The Effects of ndomethacln on Edema and Eicosanoids Changes in Rat Skeletal Muscle after Ischemia and Reperfusion Injury
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Yoon GK, Chung J, Sohn BK
- KMID: 2322521
- J Korean Soc Plast Reconstr Surg.
- 2000 Jan;27(1):72-77.
Ischemia and reperfusion of skeletal muscle occurs in acute vascular occlusion and revascularization, in elective vascular surgery, in upper and lower extremity surgery by means of a tourniquet, and in... -
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- The effect of indomethacin on the production of eicosanoids and edema during ischemia-reperfusion injury in skeletal muscle
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Chung YJ, Sohn BK, Hyun KS, Yoo SH, Ryu HK, Kim HG
- KMID: 1581031
- Korean J Physiol Pharmacol.
- 2000 Dec;4(6):525-530.
During reperfusion of skeletal muscle after ischemia, lipid mediators, mainly eicosanoids, are released and may have a role in the pathogenesis of reperfusion injury. To validate the role of eicosanoids in the ischemia-reperfusion... -
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- Liquid Chromatography-Mass Spectrometry-Based In Vitro Metabolic Profiling Reveals Altered Enzyme Expressions in Eicosanoid Metabolism
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Lee SH, Kim EJ, Lee DH, Lee WY, Chung BC, Seo HS, Choi MH
- KMID: 2373554
- Ann Lab Med.
- 2016 Jul;36(4):342-352.
- doi: 10.3343/alm.2016.36.4.342
BACKGROUND: Eicosanoids are metabolites of arachidonic acid that are rapidly biosynthesized and degraded during inflammation, and their metabolic changes reveal altered enzyme expression following drug treatment. We developed an eicosanoid... -
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- Prostaglandin E2 Receptors on Upper Respiratory Tract
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Kim JK
- KMID: 2074132
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2009 Jul;52(7):553-559.
- doi: 10.3342/kjorl-hns.2009.52.7.553
Prostaglandin (PG) E2 exerts its actions by acting on a group of G-protein-coupled receptors (GPCRs). GPCRs responding to PGE2 consist of four subtypes namely E-prostanoid 1 (EP1), E-prostanoid 2 (EP2),... -
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- The Signaling Pathway of G-protein Rac and Eicosanoid Synthesis by Titanium Particles
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Lee SS, Her JY, Woo CH, Kim JH, Chang JD
- KMID: 2105760
- J Korean Orthop Assoc.
- 2001 Aug;36(4):317-325.
PURPOSE: In order to understand the intracellular signaling pathway involving the c-fos gene expression that is caused by Titanium-particles, we analyzed the involvement of Rac, cytosolic phospholipase A2, and eicosanoids... -
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- Diverse characters of Brennan’s paw incision model regarding certain parameters in the rat
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Kumar R, Gupta S, Gautam M, Jhajhria S, Ray SB
- KMID: 2455612
- Korean J Pain.
- 2019 Jul;32(3):168-177.
- doi: 10.3344/kjp.2019.32.3.168
BACKGROUND: Brennan’s rodent paw incision model has been extensively used for understanding mechanisms underlying postoperative pain in humans. However, alterations of physiological parameters like blood pressure and heart rate, or... -
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- Effect of Dietary CLA Isomers on Apoptosis and Cell Proliferation in Colonic Mucosa of DMH-Treated Rats
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Park HS, Kwon PS, Park JH, Ha YL
- KMID: 2269681
- Korean J Nutr.
- 2003 Sep;36(7):661-666.
The study was designed to compare the anti-carcinogenic effect of conjugated linoleic acid (CLA) isomers on colon carcinogenesis in 1,2-dimethylhydrazine (DMH)-treated rats by determining the levels of apoptosis, cell proliferation,... -
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- Changes in the Levels of Eicosanoids and Isoprostane (8-iso-PGF2alpha) in the Newborn Rat Brain after Hypoxic-Ischemic Injury
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Lee HY, Jung MK, Kim JA, Chang YP, Hyun KS, Kim HG, Hwang TJ
- KMID: 2099016
- J Korean Soc Neonatol.
- 2000 May;7(1):45-53.
PURPOSE: The changes in the levels of eicosanoids and isoprostane (8-iso-PGF2alpha) were investigated in brain tissue of 7 day-old rats after hypoxic-ischemic (HI) injury. METHODS: The 7 day-old newborn rats... -
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- Simultaneous HPLC analysis of arachidonic acid metabolites in biological samples with simple solid phase extraction
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Kim HG, Huh YN, Park KS
- KMID: 2071837
- Korean J Physiol Pharmacol.
- 1998 Dec;2(6):779-786.
A reversed-phase high-performance liquid chromatography (RP-HPLC) has been developed to analyze the metabolites of arachidonic acid based on the specificities of ultraviolet absorption of these various metabolites and is sensitive to the nanogram... -
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- Imperatorin Suppresses Degranulation and Eicosanoid Generation in Activated Bone Marrow-Derived Mast Cells
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Jeong KT, Lee E, Park NY, Kim SG, Park HH, Lee J, Lee YJ, Lee E
- KMID: 2380290
- Biomol Ther.
- 2015 Sep;23(5):421-427.
- doi: 10.4062/biomolther.2015.023
Imperatorin has been known to exert many biological functions including anti-inflammatory activity. In this study, we investigated the inhibitory effects of imperatorin on the production of inflammatory mediators in mouse... -
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- The Change of Histologic Features and Eicosanoids Level in Rat Testicular Ischemia-Reperfusion Injury
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Lee SJ, Lee GH, Kim HJ, Kim HG, Kim EJ
- KMID: 2292529
- Korean J Urol.
- 2002 Dec;43(12):1086-1092.
PURPOSE: It has been suggested that prostaglandins (PGs) play an important role in ischemia-reperfusion (IR) organ injury. However, the significance of PGs is not well documented for a testicular IR... -
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- Effect of CLA (Conjugated Linoleic Acid) on the Anti-Atherosclerotic Factors in Human Hepatoma HepG2 Cells
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Oh H, Mun H, Lee M
- KMID: 2269778
- Korean J Nutr.
- 2004 Apr;37(3):182-192.
Conjugated linoleic acid (CLA) is the mixture of positional and geometric isomers of linoleic acid (LA), which is found abundantly in dairy products and meats. This study was performed to... -
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- Effect of Dietary Iron Levels on Lipid Metabolism, Antioxidative and Antithrombogenic Capacities in 16-month-old Rats
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Kim SK, Park J, Kim MK
- KMID: 2257457
- Korean J Nutr.
- 2004 May;37(4):273-280.
This study was conducted to examine the effect of dietary iron levels on lipid metabolism, antioxidative and antithrombogenic capacities in 16-month-old rats. Thirty-two Sprague-Dawley male 16-month-old rats weighing 618 +/-... -
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- Effects of Cyclooxygenase and Lipoxygenase Inhibitors on the Proliferation of Colon Cancer Cells and Their Production of Eicosanoids
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Lee HS, Kim EJ, Oh YS, Cho HJ, Park JH
- KMID: 1804431
- Cancer Res Treat.
- 2001 Oct;33(5):404-413.
PURPOSE: Epidemiological and laboratory studies suggest that nonsteroidal antiinflammatory drugs (NSAIDs) reduce the risk of colon cancer and that the inhibition of colon cancer is mediated through modulation of eicosanoid... -
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- Effect of Different Amount of Dietary n-3 PUFA on Colon Carcinogenesis in DMH-treated Rats
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Park HS, Kwak HK, Kim MS
- KMID: 2269915
- Korean J Nutr.
- 2005 Dec;38(10):807-816.
The objective of the study was to observe the effect of n-3 PUFA on cell proliferation and apoptosis by determining mRNA and protein of COX-2 and eicosanoid product and the... -
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- Oxidative Stress and Molecular Reactions in Arteriogenic Erectile Dysfunction
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Azadzoi KM, Siroky M
- KMID: 2172277
- Chonnam Med J.
- 2009 Apr;45(1):1-8.
- doi: 10.4068/cmj.2009.45.1.1
Vascular disorders are the leading causes of organic erectile dysfunction (ED). Most cases of arteriogenic ED are associated with vascular risk factors such as hypercholesterolemia, atherosclerosis, diabetes mellitus, hypertension, and... -
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