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Response to Treatment of Helicobacter pylori-associated Dyspepsia: Eradication of Helicobacter pylori or Correction of Gastric or Intestinal Dysbiosis?

Abraham P, Pereira V

  • KMID: 2417395
  • J Neurogastroenterol Motil.
  • 2018 Jul;24(3):502-502.
  • doi: 10.5056/jnm18091
No abstract available.
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Pathogenic role of the gut microbiota in gastrointestinal diseases

Nagao-Kitamoto H, Kitamoto S, Kuffa P, Kamada N

The gastrointestinal (GI) tract is colonized by a dense community of commensal microorganisms referred to as the gut microbiota. The gut microbiota and the host have co-evolved, and they engage...
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The interplay between host immune cells and gut microbiota in chronic inflammatory diseases

Kim D, Zeng MY, Núñez G

Many benefits provided by the gut microbiota to the host rely on its intricate interactions with host cells. Perturbations of the gut microbiota, termed gut dysbiosis, affect the interplay between...
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Gut Microbiota in Health and Probiotics in Functional Bowel Disease

Rhyou JH

Microorganisms coexist in the human body and its function is essential to maintain normal physiology and homeostasis. Microbiota refers to the entire population of microorganisms that colonizes a particular location;...
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Fecal microbiota transplantation for refractory Crohn's disease

Bak SH, Choi HH, Lee J, Kim MH, Lee YH, Kim JS, Cho YS

Approximately one-third of patients with Crohn's disease do not respond to conventional treatments, and some experience significant adverse effects, such as serious infections and lymphoma, and many patients require surgery...
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Host-microbial Cross-talk in Inflammatory Bowel Disease

Nagao-Kitamoto H, Kamada N

A vast community of commensal microorganisms, commonly referred to as the gut microbiota, colonizes the gastrointestinal tract (GI). The involvement of the gut microbiota in the maintenance of the gut...
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Systemic Sclerosis and Microbiota: Overview of Current Research Trends and Future Perspective

Kim S, Chun SH, Park HJ, Lee SI

The commensal microbiota contributes to the maintenance of immune homeostasis in the human body. Autoimmunity can be aggravated or alleviated by the microbiota, which affects both innate and adaptive immune...
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Interplay between Intestinal Microbiota and Host Immune System

Mazmanian , Lee YK

Whether we are aware or not, diverse microorganisms are living on almost all environmentally exposed surfaces on our body without eliciting harmful immune responses. In fact, recent understanding from numerous...
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Is It Useful to Administer Probiotics Together With Proton Pump Inhibitors in Children With Gastroesophageal Reflux?

Belei O, Olariu L, Dobrescu A, Marcovici , Marginean

  • KMID: 2417272
  • J Neurogastroenterol Motil.
  • 2018 Jan;24(1):51-57.
  • doi: 10.5056/jnm17059
BACKGROUND/AIMS: Gastroesophageal reflux disease (GERD) is a frequent condition diagnosed in children and treated with proton pump inhibitors (PPI). Long-term PPI administration can alter intestinal bacterial population by suppressing the...
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Significance of Skin Barrier Dysfunction in Atopic Dermatitis

Kim BE, Leung DY

The epidermis contains epithelial cells, immune cells, and microbes which provides a physical and functional barrier to the protection of human skin. It plays critical roles in preventing environmental allergen...
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Obesity and Dysbiosis

Kim SM

Recent studies have described an association between obesity and gut microbiota, suggesting that the latter might play a critical role in the development of the former. Possible mechanisms by which...
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Intestinal Microbiota Contributes to Energy Balance, Metabolic Inflammation, and Insulin Resistance in Obesity

Cavallari , Schertzer

Obesity is associated with increased risk of developing metabolic diseases such as type 2 diabetes. The origins of obesity are multi-factorial, but ultimately rooted in increased host energy accumulation or...
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Interpretation of the hygiene and microflora hypothesis for allergic diseases through epigenetic epidemiology

Bae JM

The hygiene hypothesis (HH) proposed by Strachan in 1989 was expanded to explain the inverse association between the occurrence of allergy disorders and the risk of infectious diseases and parasite...
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High-fat-diet-modulated Gut Microbiota Promotes Intestinal Carcinogenesis

Ali I, Koh YS

Gut microbiota play a critical role in the development of intestinal cancer. Dietary changes cause dysbiosis of gut microbiota that mediates production of dietary factors triggering intestinal cancer. Genetic and...
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Probiotics as a Potential Immunomodulating Pharmabiotics in Allergic Diseases: Current Status and Future Prospects

Sharma G, Im SH

The prevalence of allergic disorders has dramatically increased over the past decade, particularly in developed countries. Apart from gastrointestinal disorders, neoplasia, genital and dermatological diseases etc., dysregulation of gut microbiota...
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Microbiota in T-cell homeostasis and inflammatory diseases

Lee N, Kim WU

The etiology of disease pathogenesis can be largely explained by genetic variations and several types of environmental factors. In genetically disease-susceptible individuals, subsequent environmental triggers may induce disease development. The...
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Changes in Gastric Microbiota during Gastric Carcinogenesis

Lee SY

After World War II, the incidence of gastric cancer decreased rapidly in most of the developed countries; however, it remained high in countries where secondary prevention of gastric cancer is...
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Intestinal microbiota, chronic inflammation, and colorectal cancer

Park CH, Eun CS, Han DS

In addition to genetic and epigenetic factors, various environmental factors, including diet, play important roles in the development of colorectal cancer (CRC). Recently, there is increasing interest in the intestinal...
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Why is it so difficult to evaluate faecal microbiota transplantation as a treatment for ulcerative colitis?

Fairhurst , Travis SP

Faecal microbiota transplantation (FMT) has recently re-emerged as a viable therapeutic option for colonic disorders. Its efficacy has been proved in the treatment of Clostridium difficile infection which has encouraged...
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Microbiome in the Gut-Skin Axis in Atopic Dermatitis

Lee SY, Lee E, Park YM, Hong SJ

The microbiome is vital for immune system development and homeostasis. Changes in microbial composition and function, termed dysbiosis, in the skin and the gut have recently been linked to alterations...
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