- Molecular biologic mechanism of drug resistance in cancer chemotherapy
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Kim WY, Kim BG
- KMID: 1993033
- Korean J Obstet Gynecol.
- 2007 Feb;50(2):255-265.
Development of chemoresistance is a persistent problem during the treatment of local and disseminated disease. Elucidation of the mechanism involved in multiple drug resistance has been a major goal of... -
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- Multidrug Resistance in Cancer Chemotherapy
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Kim JH
- KMID: 2320354
- Yeungnam Univ J Med.
- 1996 Jun;13(1):11-21.
- doi: 10.12701/yujm.1996.13.1.11
No abstract available. -
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- Treatment of Neisseria gonorrhoeae in the Era of Multidrug Resistance
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Chae JY, Oh MM
- KMID: 1839383
- Korean J Urogenit Tract Infect Inflamm.
- 2015 Apr;10(1):12-18.
- doi: 10.14777/kjutii.2015.10.1.12
Neisseria gonorrhoeae (NG) is becoming increasingly less susceptible to the extended spectrum cephalosporin (ESC), which has been recommended for first-line treatment, and cases of treatment failure are being reported globally.... -
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- Lamivudine and adefovir combination therapy in lamivudine-resistant HBeAg-positive chronic hepatitis B patients
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Lee HC
- KMID: 2305780
- Korean J Med.
- 2009 Dec;77(6):713-715.
The introduction of lamivudine (LAM) has opened a new era for the treatment of chronic hepatitis B (CHB). However, the major drawback of LAM, which currently limits its use as... -
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- The Prevalence of Initial Drug Resistance among Pulmonary Tuberculosis Patients
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Kong JH, Lee SS, Kang HY, Park JS
- KMID: 2319014
- Tuberc Respir Dis.
- 2008 Feb;64(2):95-101.
BACKGROUND: Drug resistant tuberculosis (TB) in patients who have not received previous TB treatment (initial drug resistance) is a serious problem for the control of TB. However, prevalence of initial... -
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- The Drug Resistance of Mycobacterium tuberculosis in Seongnam
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Kim EY, Lee HW, Lee JW, Nahm CH, Choi JW, Pai SH, Kim JJ
- KMID: 2135534
- J Clin Pathol Qual Control.
- 1998 Jun;20(1):231-237.
BACKGROUND: According to the nationwide survey of tuberculosis from 1965 to 1995, the incidence and drug resistance rate of tuberculosis have been decreased in Korea, but the prevalence of multidrug... -
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- Acquisition of methicillin resistance and progression of multiantibiotic resistance in methicillin-resistant Staphylococcus aureus
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Ito T, Hiramatsu
- KMID: 711594
- Yonsei Med J.
- 1998 Dec;39(6):526-533.
- doi: 10.3349/ymj.1998.39.6.526
Methicillin-resistant Staphylococcus aureus (MRSA) produces specific penicillin-binding protein, PBP2', which shows remarkably low affinities to most beta-lactam antibiotics except those such as penicillin G and ampicillin. The region surrounding mecA... -
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- The Role of Integrons in the Spread of Multi-drug Resistance
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Jang SJ
- KMID: 2224686
- Korean J Clin Microbiol.
- 2005 Apr;8(1):1-9.
The liberal use of antibiotics in human medicine and animal husbandry has promoted the spread of multiple antibiotic resistance. Molecular mechanisms for the acquisition of resistance genes by integron-mediated recombination... -
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- Mutations in folP1, rpoB, and gyrB associated with multiple drug resistance in Mycobacterium leprae isolates from South Korea
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Lee SB, You EY, Kang TJ, Kim SK, Kim JP, Ko YH, Chae GT
- KMID: 1516978
- Korean Lepr Bull.
- 2003 Jul;36(1):3-9.
The emergence of multiple drug resistant Mycobacterium leprae has emphasized the need for early decision of effective antileprosy drug in the treatment for leprosy patients. Mutations in the genes associated... -
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- Antimicrobial Resistance in Escherichia coli Isolated from Healthy Volunteers of the Community
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Lee JM, Hwang KW, Jegal S
- KMID: 2224735
- Korean J Clin Microbiol.
- 2007 Apr;10(1):32-36.
BACKGROUND: We monitored the prevalence of antimicrobial resistance and the pattern of multiple drug resistance in Escherichia coli isolated from healthy people in the community. METHODS: We performed antimicrobial susceptibility testing... -
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- Development of Multidrug Resistance during Standardized Treatment in a Patient with Drug-Sensitive Tuberculosis
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Jeong YJ, Kang HJ, Choi SM, Han SK, Yim JJ
- KMID: 2263562
- Korean J Med.
- 2012 May;82(5):614-617.
Standard short-course chemotherapy (SSC) is recommended for new patients with pulmonary tuberculosis (TB). This approach has been regarded as among the most effective tools for preventing the development of resistance... -
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- The Prevalence and Risk Factors of Drug Resistant Pulmonary Tuberculosis Investigated at One University Hospital in Seoul
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Kim DK, Kim MO, Kim TH, Sohn JW, Yoon HJ, Shin DH, Park SS
- KMID: 2009832
- Tuberc Respir Dis.
- 2005 Mar;58(3):243-247.
- doi: 10.4046/trd.2005.58.3.243
BACKGROUND: The prevalence of tuberculosis is slowly decreasing in Korea. However, the drug-resistance of pulmonary tuberculosis is a major risk factor of treatment failure. Moreover, the National Surveillance System has... -
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- Aeromonas hydrophila and Aspiration Pneumonia: A Diverse Presentation
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Mukhopadhyay C, Bhargava A, Ayyagari A
- KMID: 1091053
- Yonsei Med J.
- 2003 Dec;44(6):1087-1090.
- doi: 10.3349/ymj.2003.44.6.1087
Although there are ever increasing reports of extraintestinal human infections caused by Aeromonads, in both immunocompromised and immunocompetent patients, respiratory tract infections remain uncommon. We describe a case of aspiration... -
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- Drug-Resistant Extrapulmonary Tuberculosis
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Cho OH, Park KH, Park SY, Moon SM, Chong YP, Kim MN, Lee SO, Choi SH, Woo JH, Kim YS, Kim SH
- KMID: 2170347
- Infect Chemother.
- 2011 Jun;43(3):258-261.
- doi: 10.3947/ic.2011.43.3.258
The prevalence and pattern of drug-resistant extrapulmonary tuberculosis (TB) is not well characterized in Korea. Therefore, we assessed the incidence of drug resistance for extrapulmonary TB in adult patients at... -
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- Emergence and spread of antimicrobial resistance of Streptococcus pneumoniae in Korea
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Song JH
- KMID: 711597
- Yonsei Med J.
- 1998 Dec;39(6):546-553.
- doi: 10.3349/ymj.1998.39.6.546
Pneumococcal resistance has become a global issue during the past three decades. One of the major foci of pneumococcal resistance worldwide is the Asian region including Korea, Japan, and Hong... -
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- A role of Cyclosporine A that suppresses multi-drug resistance (MDR) in the secondary chemotherapy drug resistant cell line of ovarian cancer
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An CS, Kim SY, Park CM
- KMID: 2143513
- Korean J Gynecol Oncol.
- 2006 Dec;17(4):286-293.
OBJECTIVE: Resistant, recurrent ovarian cancer patients who had first chemotherapy with Cisplatin have showed low reactivity and high recurrence in the secondary chemotherapy. Therefore, multi-drug resistance (MDR) to chemotherapy is... -
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- Correlation of multidrug resistance gene expression with hestologic grade in locally advanced breast cancer
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Bae JW, Kim IS, Hwang JW
- KMID: 1694328
- J Korean Cancer Assoc.
- 1993 Jun;25(3):376-382.
No abstract available. -
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- A Case of Acute Leukemia Remitted by Adding Cyclosporin-A Previously Failed with Induction Therapy
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Park SB, Choe BK, Kim HS, Kang CM
- KMID: 2335503
- J Korean Pediatr Soc.
- 2000 Jul;43(7):988-992.
Clinical chemotherapy refractoriness is characterized by resistance to multiple drugs. Multidrug resistance(MDR) is caused by over-reactivity of a unidirectional drug efflux pump, transmembrane glycoprotein(P-glycoprotein), which is encoded by the MDR1 gene. P-glycoprotein leads... -
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- A Trend in Acquired Drug Resistances of Tuberculosis Patients Registered in Health Centers from 1981 to 2004
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Chang CL, Lee EY, Park SK, Jeong SH, Park YK, Choi YW, Kim HJ, Lew WJ, Bai GH
- KMID: 2318747
- Tuberc Respir Dis.
- 2005 Dec;59(6):619-624.
BACKGROUND: The drug resistance rate in tuberculosis patients with history of chemotherapy is an important indicator of for evaluation of appropriateness of treatment regimens and compliance of patients. This... -
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- Carbapenem-Resistant Acinetobacter baumannii
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Bae IK, Jeong SH, Lee K
- KMID: 2224853
- Korean J Clin Microbiol.
- 2012 Mar;15(1):1-8.
- doi: 10.5145/KJCM.2012.15.1.1
Clinical isolates of Acinetobacter spp. in Korea exhibit higher antimicrobial resistance rates than in foreign countries and frequently show multi-drug resistance. Approximately 67% (272/405) of Acinetobacter baumannii isolates collected from... -
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