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Basic Principles of Drug Interaction

Chun BG

  • KMID: 2334629
  • J Korean Soc Biol Psychiatry.
  • 2000 Jul;7(1):3-13.
There is nothing that is harmless ; the dose alone decides that something is no poison(Paracelsus. 1493-1541). So, in a point of view to maximize the therapeutic efficacy of drug...
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Antidepressants and Related Drug Interactions

Lee MS

  • KMID: 2334631
  • J Korean Soc Biol Psychiatry.
  • 2000 Jul;7(1):21-33.
As the clinical practice of using more than one drug at a time increase, the clinician is faced with ever-increasing number of potential drug interactions. Although many interactions have little...
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Drug Interactions of Frequently Prescribed Drugs

Jang IJ

No abstract available.
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Drug-drug Interactions between Psychotropic Agents and Other Drugs in Physically Ill Patients: Experience of Consultation-liason in Korea University Hospital

Lee MS, Lee HJ

  • KMID: 2334592
  • J Korean Soc Biol Psychiatry.
  • 1999 Jul;6(1):49-66.
Polypharmacotherapy, both psychotropic and nonpsychotropic, is widespread in various situations including psychiatric hospitals and general hospitals. As the clinical practice of using more than one drug at a time increase,...
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Drug-nutrient Interactions in Elderly Patients

Rho J

Physiological changes associated with aging affect the absorption, distribution, metabolism, and excretion of drugs and thus therapeutic outcomes. These changes may be further amplified by interactions with nutrients. The purpose...
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Anesthetic Drug Interactions

Ryu KH

No Abstract available.
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An overview of pharmacodynamic drug interaction with isobole and response surface model in anesthesia

Choi BM

Drug interaction is the principal concept of anesthetic practice. Typically, drug interactions are divided into three categories i.e., additive, synergistic, or infra-additive interactions. Pharmacodynamic drug interactions are typically described using...
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Drug Interactions of Antiepileptic Drugs

Shin JG

  • KMID: 1816474
  • J Korean Epilepsy Soc.
  • 2000 Dec;4(2):119-123.
No abstract available.
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The contraindication of comedication drugs and drug utilization review

Park JY, Park KW

A drug interaction can be defined as an interaction between a drug and other drugs that prevent the drug from performing as expected. These processes may include alterations in the...
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Lithium Intoxication: A Possible Interaction with Moxifloxacin

Kayipmaz S, Altınöz , Ok NE

Lithium is a well-known treatment for patients with mood disorders. Intoxication by lithium may be lethal particularly in elderly due to altered pharmacokinetics, renal impairment or multiple drug use. We...
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Reversible Dysphasia and Statins

Davies GR

This paper presents a case of reversible dysphasia occurring in a patient prescribed atorvastatin in combination with indapamide. A milder dysphasia recurred with the prescription of rosuvastatin and was documented...
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Drug interaction

Kim MY

  • KMID: 2295307
  • J Korean Acad Fam Med.
  • 1999 Sep;20(9):1077-1083.
No abstract available.
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Inhibitory Drug Interaction

Roh HK

  • KMID: 2349093
  • J Korean Med Assoc.
  • 1997 Jan;40(1):34-39.
No abstract available.
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Drug Interaction in Renal Excretion

Lee KH

  • KMID: 2349091
  • J Korean Med Assoc.
  • 1997 Jan;40(1):19-23.
No abstract available.
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Therapeutic Drug Monitoring(TDM) of Psychotropic Drugs

Yang BH

  • KMID: 1834622
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):56-65.
Clinicians can use therapeutic drug monitoring(TDM) to optimise dosage decisions with psychotropic drugs, in order to maximize efficacy and prevent toxicity, especially when individuals are nonresponsive to treatment or vulnerable...
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Use of Antiepileptic Drugs in the Elderly

Kwon OY

  • KMID: 1480897
  • J Korean Epilepsy Soc.
  • 2008 Dec;12(2):67-77.
The incidence of epilepsies and seizures is higher in the age group over 65-year-old than any other age group. The reduction of the dosages of antiepileptic drugs is recommended and...
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Concerns on Drug Interactions between Proton Pump Inhibitors and Clopidogrel: Unsafe Perspective

Lee K, Han SH

  • KMID: 2263938
  • Korean J Med.
  • 2011 Jul;81(1):34-39.
Clopidogrel is a prodrug that is converted in the liver to an active thiol metabolite, which irreversibly inhibits the platelet P2Y12 adenosine diphosphate receptor. This mechanism requires cytochrome P450 2C19...
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Prediction of Drug–Drug Interactions by Using Profile Fingerprint Vectors and Protein Similarities

Dere S, Ayvaz S

OBJECTIVES: Drug–drug interaction (DDI) is a vital problem that threatens people's health. However, the prediction of DDIs through in-vivo experiments is not only extremely costly but also difficult as many...
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Understanding the Drug-Drug Interaction

Yim DS

Drug-drug interaction (DDI) is defined as a change in effect or safety of a drug by another co-administered drug. The fact that more than half of the market withdrawal cases...
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Pharmacokinetics and Therapeutic Drug Monitoring of Newer Antiepileptic Drugs

Seo DW

  • KMID: 1449313
  • J Korean Epilepsy Soc.
  • 2011 Dec;15(1):1-9.
Recently a newer generation of antiepileptic drugs has been developed and rational polytherapy has become popular in everyday clinical practice for epilepsy management. All of newer antiepileptic drugs (AED) have...
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