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Drug Hypersensitivity Syndrome Induced by Leflunomide

Kim HW, Park HC, Kim JE, Ko JY, Ro YS

  • KMID: 2247252
  • Korean J Dermatol.
  • 2013 Mar;51(3):226-227.
No abstract available.
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Drug Hypersensitivity Syndrome Associated Dapsone

Kim JG, Kim CY

  • KMID: 2247465
  • Korean J Dermatol.
  • 2012 May;50(5):475-476.
No abstract available.
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Hypersensitivity myocarditi caused by ceused by cafadroxil

Shin TR, Choi HY, Chang YH, Cho YJ

  • KMID: 1543170
  • Korean J Allergy.
  • 1997 Jun;17(2):186-191.
Hypersensitivity myocarditis is an inflammatory disease of the myocardium usually related to drug allergy. The clinical manifestation may be nonspecific, and the diagnosis is seldom suspected or established during the...
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Recent progress of elucidating the mechanisms of drug hypersensitivity

Hashizume

Recent technical approaches to investigating drug hypersensitivity have provided a great deal of information to solve the mechanisms that remain poorly understood. First, immunological investigations and in silico analysis have...
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Drug hypersensitivity to various antihistamines with cross-reactions

Kim YU, Lee J

Antihistamines (histamine receptor antagonists) are widely prescribed medicines in the treatment of allergic disorders, especially the symptoms of hypersensitivity reactions, mainly blocking the activity of vasoactive amines to their receptors....
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Drug Rash With Eosinophilia and Systemic Symptoms Syndrome Induced by Chloral Hydrate in Early Childhood

Yoo SD, Kim SG, Kim SH, Kim HY

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, also known as drug-induced hypersensitivity syndrome (DIHS), is a rare, acute and severe life-threatening systemic disease. DRESS syndrome is characterized by...
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Update on the Management of Nonsteroidal Anti-Inflammatory Drug Hypersensitivity

Yeung WY, Park HS

The clinical phenotypes of nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity are heterogeneous with various presentations including time of symptom onset, organ involvements, and underlying pathophysiology. Having a correct diagnosis can be...
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Self-report prevalence and associated factors to drug hypersensitivity in Mexican young adults

Bedolla-Barajas M, Puente-Fernández C, Flores-Merino MV, Morales-Romero J, Domínguez-García MV

BACKGROUND: Drug hypersensitivity is defined as any unfavorable reaction that occurs after the administration of any drug. It may or may not be mediated by the involvement of the immune...
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A case of vancomycin-induced drug hypersensitivity syndrome

Min KS, Choi WY, Song ES, Han DK, Cho YK, Ma JS

Drug hypersensitivity syndrome (DHS) has rarely been reported in association with vancomycin treatment. Here, we describe an 11-year-old girl who developed fever and a maculopapular rash on day 18 of...
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Clinical applications of drug desensitization in the Asia-Pacific region

Thong BY

Drug desensitization is the induction, within hours to days, of a temporary state of tolerance to a drug which the patient has developed a hypersensitivity reaction to. It may be...
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Anticonvulsant Hypersensitivity Syndrome Associated with Epstein-Barr Virus Reactivation

Chang JY, Kim SC

We describe a 59-year-old female with severe anticonvulsant hypersensitivity syndrome (AHS) associated with Epstein- Barr virus (EBV) infection. The causative drug was speculated to be carbamazepine. Recurrent EBV infection was...
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Successful desensitization of a patient with albumin hypersensitivity

Jung SY, Choi YJ, Lee SH, Kang HR, Suh DI

There have been few cases of albumin hypersensitivity reported, and there is limited information on this condition. When a patient is anaphylactic to a certain drug and no alternative drug...
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Recent applications of basophil activation tests in the diagnosis of drug hypersensitivity

Song WJ, Chang YS

Immediate-type drug hypersensitivity is an increasingly significant clinical issue; however, the diagnosis is frequently hindered due to lack of safe and precise diagnostic tests. Flow cytometry-assisted basophil activation test is...
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Effectiveness of premedication and rapid desensitization in hypersensitivity to L-asparaginase

Yoon DH, Kang SH, Kim HS, Lee JW, Yoon JS, Chung NG, Cho B

PURPOSE: L-asparaginase is a crucial chemotherapeutic agent for the treatment of acute lymphoblastic leukemia. However, hypersensitivity to L-asparaginase is common which limits its clinical use. METHODS: We performed 44 cases of...
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Anaphylactic Shock Caused by the Epidurally-Administered Hyalurinidase

Lee HK, Choi EJ, Lee PB, Nahm FS

Hyaluronidase is an enzyme that has temporary and reversible enzymatic effects on the matrix of connective tissue. When added to local anesthetics in pain treatments, it enhances their infiltration and...
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A Case of Midazolam Induced Drug Hypersensitivity Syndrome

Lee KY, Hong JW, Lee CY, Kim KH, Kim YH

  • KMID: 2301944
  • Korean J Dermatol.
  • 2009 Oct;47(10):1158-1161.
Drug hypersensitivity syndrome is defined by various combinations of severe skin eruption and systemic signs. The symptoms of this syndrome usually begin in two to six weeks after the exposure...
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A Case of Podostroma Cornu-Damae Intoxication Similar to Drug Hypersensitivity Syndrome

Yang JN, Kang JH, Kang YS, Seok SJ, Kim WK

  • KMID: 2267819
  • Korean J Med.
  • 2013 Aug;85(2):223-228.
The clinical aspects of intoxication can be similar to those of drug hypersensitivity syndrome, including desquamation, hematologic abnormalities, multiple organ failure, and even death. Many people consume mushrooms that they...
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Drug hypersensitivity in human immunodeficiency virus-infected patient: challenging diagnosis and management

Yunihastuti E, Widhani A, Karjadi TH

Human immunodeficiency virus (HIV)-infected patients present complex immunological alterations. Multiple drugs that usually prescribed for prevention or treatment of opportunistic infections and antiretroviral pose these patients a higher risk of...
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Drug Hypersensitivity Syndrome: A Literature Review of Associated Viral Reactivation

  • KMID: 2299508
  • Korean J Asthma Allergy Clin Immunol.
  • 2011 Jun;31(2):77-83.
Drug hypersensitivity syndrome is a severe adverse drug reaction characterized by skin eruption and systemic manifestations, such as fever, eosinophilia, lymph node enlargement, hepatitis and renal dysfunction. The pathogenic mechanism...
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A Case of Jarisch-Herxheimer Reaction Complicated by Fatal Hypersensitivity Pneumonitis in a Patient with Secondary Syphilis

Kim JW

  • KMID: 1640010
  • Korean J Dermatol.
  • 2006 Sep;44(9):1114-1118.
Jarisch-Herxheimer reaction (JHR) is a relatively common, acute febrile hypersensitivity reaction that follows administration of antibiotic therapy for early syphilis. Sedation and general supportive measures are the mainstay of therapy...
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