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Comparison of two dosing regimens of aminoglycosides for the development of nephrotoxicity: once versus multiple daily dosing

Choi BD, Kim BN

  • KMID: 2305955
  • Korean J Med.
  • 2006 Nov;71(5):543-550.
BACKGROUND: Aminoglycosides are useful for the treatment of aerobic gram-negative infections, and this is despite the narrow therapeutic index and the potential nephrotoxicity and ototoxicity. Once daily dosing of aminoglycosides...
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Docetaxel Monotherapy as Second-Line Treatment for Pretreated Advanced Non-Small Cell Lung Cancer Patients

Ko YH, Lee MA, Hong YS, Lee KS, Park HJ, Yoo IR, Kim YS, Kim YK, Jo KH, Wang YP, Lee KY, Kang JH

BACKGROUND: Second-line chemotherapy offers advanced non-small cell lung cancer (NSCLC) patients a small, but significant increase in survival. Docetaxel is usually administered as a 3-week schedule, yet there is...
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Pulmonary BALT Lymphoma Successfully Treated with Eight Cycles Weekly Rituximab: Report of First Case and F-18 FDG PET/CT Images

Bilici A, Seker M, Ustaalioglu BBO, Canpolat N, Salepci T, Gumus M

Extra marginal-zone lymphomas of the lung is a very rare tumor and it originates from bronchial-associated lymphoid tissue. A 68-yr-old woman presented with productive cough and dyspnea. A thorax computed...
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Clinical Result of Prolonged Primary Chemotherapy in Retinoblastoma Patients

Kim JH, Yu YS, Khwarg SI, Choi HS, Shin HY, Ahn HS

This study evaluated the effects of prolonged primary chemotherapy in retinoblastoma. The data for 27 eyes in 22 children who were treated for retinoblastoma with up to 13 cycles of...
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Administration of four different doses of gabapentin reduces awakening from breakthrough pain and adverse effects in outpatients with neuropathic pain during the initial titration

Yang JY, Lee WI, Shin WK, Kim CH, Baik SW, Kim KH

BACKGROUND: Gabapentin is a safe and well-tolerated anticonvulsant with a wide therapeutic index, and it is used for neuropathic pain. The aim of this study was to compare previous dosing...
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A Case of Pneumatosis Intestinalis Associated with Sunitinib Treatment for Renal Cell Carcinoma

Choi YA, Sim EH, Lee KE, Ko SY, Seo MJ, Yang YJ, Park JC, Park SY

Sunitinib as a multitarget tyrosine kinase inhibitor is one of the anti-tumor agents, approved by the United States Food and Drug Administration to use treat gastrointestinal stromal tumor and metastatic...
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The Comparison of Mydriatic Effect Between Two Drugs of Different Mechanism

Park JH, Lee YC, Lee SY

PURPOSE: To maximize effective use of mydriatic drugs through comparing the pupillary dilation effects between 1% tropicamide and 2.5% phenylephrine. METHODS: Fifty people requiring pupillary dilation were divided into 3...
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Immediate Effects of Methylprednisolone Pulse Therapy on the Immune Response

Lee SK, Hong CS

To study the immediate effects of high-dose intravenous methylprednisolone pulse therapy on the immune mechanisms in the absence of other immunosuppressive agents, we treated ten patients with active systemic...
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Pharmacokinetics and dosage regimen of ceftriaxone in E. coli lipopolysaccharide induced fever in buffalo calves

Dardi MS, Sharma SK, Srivastava AK

  • KMID: 1114856
  • J Vet Sci.
  • 2005 Jun;6(2):147-150.
The present study was planned to investigate the pharmacokinetics of ceftriaxone in experimentally induced febrile buffalo calves (n = 5). The fever was induced by intravenous injection of E.coli lipopolysaccaride...
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Short Term Effects of Topical Cyclosporine and Viscoelastic on the Ocular Surfaces in Patients with Dry Eye

Moon JW, Lee HJ, Shin KC, Wee WR, Lee JH, Kim MK

PURPOSE: To compare the short term effects of topical 0.05% cyclosporine (CsA) and a mixture of 0.08% chondroitin sulfate and 0.06% sodium hyaluronate (CS-HA) on dry eye ocular surfaces. ...
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Subcutaneous pharmacokinetics and dosage regimen of cefotaxime in buffalo calves (Bubalus bubalis)

Sharma SK, Srivastava AK

The pharmacokinetics and dosage regimen of cefotaxime following its single subcutaneous administration (10 mg/ kg) were investigated in buffalo calves. Plasma and urine samples were collected over 10 and 24 h post administration, respectively....
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Economic Burden Can Be the Major Determining Factor Resulting in Short-Term Intermittent and Repetitive Ustekinumab Treatment for Moderate-to-Severe Psoriasis

Choi CW, Choi JY, Kim BR, Youn SW

BACKGROUND: The continuous use of biologic agents in the treatment of psoriasis has been reported to result in successful and sustained therapeutic effects and safety. However, some patients choose intermittent...
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A Case of Refractory Pediatric Crohn's Disease with a Successful Treatment by Infliximab Therapy

Park SH, Jeen YT, Chun HR, Kim DI, Baeck CW, Kim YS, Chun HJ, Lee HS, Um SH, Choi JH, Kim CD, Ryu HS, Hyun JH

  • KMID: 772847
  • Korean J Gastroenterol.
  • 2005 Oct;46(4):297-301.
Crohn's disease is a chronic inflammatory bowel disease which affects mainly children and young adults, and its cause remains unknown so far. Infliximab, a monoclonal antibody to the pivotal cytokine...
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Management of Malaria in Thailand

Udomsak S, Srivicha K, Nanthaphorn P, Sornchai L

The purpose of treatment for uncomplicated malaria is to produce a radical cure using the combination of: artesunate (4 mg/kg/day) plus mefloquine (8 mg/kg day) for 3 days; a fixed...
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A Case of Severe Bevacizumab-induced Ischemic Pancolitis, Treated with Conservative Management

Lee HN, Lee MA, Kim SW, Lim Y, Lee H, Lee HM, Won HS, Chun SH

Bevacizumab (Avastin(R)) is a monoclonal antibody against the vascular endothelial growth factor (VEGF) receptor that increases the overall survival rate when added to standard chemotherapy regimens in patients with metastatic...
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Early versus Late Intravitreal Triamcinolone Acetonide for Macular Edema associated with Branch Retinal Vein Occlusion

Oh JY, Seo JH, Ahn JK, Heo JW, Chung H

PURPOSE: To compare the effect of early versus late intravitreal injection of triamcinolone in patients with macular edema due to branch retinal vein occlusion (BRVO). METHODS: Twenty eyes...
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Growth hormone replacement therapy in adults with growth hormone deficiency; thrice weekly low dose administration

Chung YS, Lee HC, Hwang SK, Paik IK, Lee JH, Huh KB

Recent reports on growth hormone (GH) therapy have shown that GH has various beneficial effects in GH deficient adults. In most of these studies, GH was administered daily. Because GH...
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Evaluation of the effect of a 3rd GnRH injection administered six days after the 2nd GnRH injection of Ovsynch on the reproductive performance of Japanese black cows

Gaja AO, Hamana K, Kubota C, Kojima T

This study was designed to evaluate the reproductive performance of Japanese black cows following the 3rd injection of gonadotropin releasing hormone (GnRH) analogue administered concurrently with Ovsynch-based treatment on day...
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Anti-TNF-alpha Therapy for Ankylosing Spondylitis

Son JH, Cha SW

BACKGROUND: This review evaluated the safety and efficacy of etanercept in patients with ankylosing spondylitis (AS). METHODS: Of 59 patients with AS, this study reviewed 11 patients who were refractory to...
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Current concepts in the management of rheumatoid arthritis

Tanaka Y

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by inflammation and joint destruction that causes significant morbidity and mortality. However, the combined use of methotrexate, a synthetic disease-modifying antirheumatic...
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