- Effects of Dextromethorphan on the Development of Tachyphylaxis to Sciatic Nerve Blockade Induced by 2-Chloroprocaine in the Rat
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Park MS, Lee KC, Kim TY
- KMID: 2104732
- J Korean Pain Soc.
- 1996 Jun;9(1):39-45.
Tachyphylaxis to local anesthetics has shown to be promote longer interanalgesic intervals between injections. Previous study demonstrated thermal hyperalgesia accelerates development of tachyphylaxis to sciatic nerve blockade in rats, while... -
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- Serotonin Syndrome After an Overdose of Dextromethorphan and Chlorpeniramine: Two Case Reports
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Jung KY, Yun SH, Jung HM, Kim JH, Han SB, Kim JS, Paik JH
- KMID: 1482713
- J Korean Soc Clin Toxicol.
- 2013 Jun;11(1):19-22.
Dextromethorphan and chlorpeniramine are common ingredients of over-the-counter (OTC) cough pills. They are known to be safe when used alone, however, combination with other serotonergic drugs or use of an... -
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- Improved Bulbar Function in Amyotrophic Lateral Sclerosis after Nuedexta (Dextromethorphan and Quinidine) Treatment
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Cho HJ, Park JM, Park JS
- KMID: 2454844
- J Korean Neurol Assoc.
- 2019 May;37(2):171-173.
- doi: 10.17340/jkna.2019.2.9
Nuedexta (dextromethorphan and quinidine) is an Food and Drug Administration approved medication for pseudobulbar affect. Interestingly, this drug was recently reported to improve speech, swallowing, and the ability to handle... -
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- Effects of Preincisional Infiltration with Bupivacaine and Oral Dextromethorphan on Postoperative Pain in Uvulopalatopharyngoplasty
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Kim BG, Jung DG, Park SY, Lee DM, Auo HJ, Kim MW
- KMID: 2141364
- Korean J Otolaryngol-Head Neck Surg.
- 2002 Nov;45(11):1077-1080.
BACKGROUND AND OBJECTIVES: Uvulopalatopharyngoplasty is one of the most painful surgical procedures in otolaryngology. Repetitive nociceptive impulses from injured peripheral tissues and activation of N-methyl-D-aspartic acid (NMDA) receptors induce central... -
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- A Case of the Dextromethorphan Hydrobromide Induced Mood Disorder with Manic Features
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Choi MJ, Min SK
- KMID: 2287006
- Korean J Psychopharmacol.
- 1997 Apr;8(1):148-154.
The authors report a case of dexfromethorphan induced mood disorder with the review of literafures. The patient is a 19-year old female who had been taking dextromethorphan hydrobromide (trade name... -
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- Effects of Ambroxol, S-carboxymethylcysteine, Dextromethorphan and Noscapine on Mucin Release from Airway Goblet Cells
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Heo HJ, Lee HJ, Yoon CS, Lim SP, Seok JH, Seo UK, Lee CJ
- KMID: 2071614
- Korean J Physiol Pharmacol.
- 2005 Dec;9(6):323-326.
In the present study, we investigated whether ambroxol, S-carboxymethyl-L-cysteine, dextromethorphan and noscapine affect mucin release from airway goblet cells. Confluent primary hamster tracheal surface epithelial cells were metabolically radiolabeled and... -
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- Delirium during the Treatment of Postherpetic Neuralgia: A case report
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Yu SB, Shin SW, Baek SH, Kim CH, Kim KH, Kim HK
- KMID: 2104866
- J Korean Pain Soc.
- 2004 Dec;17(2):255-258.
- doi: 10.3344/jkps.2004.17.2.255
Postherpetic neuralgia is sequelae to a herpes zoster infection. It represents with intractable burning pain, allodynia and paroxysmal lancinating pain. Although various therapeutic modalities have been applied to relieve these... -
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- Effects of Peritonsillar Infiltration with Bupivacaine and Oral Dextromethorphan on Post-Tonsillectomy Pain
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Jung DG, Park SY, Park HS, Lee SH, Lim PK, Cho JE
- KMID: 2115407
- Korean J Otolaryngol-Head Neck Surg.
- 1999 Aug;42(8):1031-1034.
BACKGROUND AND OBJECTIVES: Peripheral tissue or nerve injury often leads to post-injury pain hypersensitivity caused by peripheral and central sensitization. Central sensitization which plays a significant role is triggered by... -
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- Dextromethorphan Pretreatment Does not Reduce the Tourniquet Pain in Normal Volunteers
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Chung SR, Choi Y, Leem JW, Min HK, Jun HJ, Park TS
- KMID: 2031554
- Korean J Anesthesiol.
- 2000 Aug;39(2):153-159.
- doi: 10.4097/kjae.2000.39.2.153
BACKGROUND: Dextromethorphan (DEX) is an NMDA receptor antagonist which has recently been introduced for the treatment of chronic pain mainly to reduce the central sensitization component of pain. It is... -
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- Prediction and visualization of CYP2D6 genotype-based phenotype using clustering algorithms
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Kim EY, Shin SG, Shin JG
- KMID: 2390935
- Transl Clin Pharmacol.
- 2017 Sep;25(3):147-152.
- doi: 10.12793/tcp.2017.25.3.147
This study focused on the role of cytochrome P450 2D6 (CYP2D6) genotypes to predict phenotypes in the metabolism of dextromethorphan. CYP2D6 genotypes and metabolic ratios (MRs) of dextromethorphan were determined... -
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- Neuroprotective Effects of Magnesium Sulfate and Dextromethorphan on Cerebral Ischemia after Middle Cerebral Artery Occlusion in Rats
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Mok JH, Kwon JT, Lee YB, Kim YB, Min BK, Hwang SN, Choi DY, Suk JS
- KMID: 2188501
- J Korean Neurosurg Soc.
- 1999 Oct;28(10):1389-1397.
OBJECTIVE: Much evidence implicates that excitatory amino acids play a crucial role in neuronal death under ischemic conditions, of which the neurotoxic effects are thought to be mediated by overstimulation... -
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