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Paraganglioma of the Bladder

Seon IC, Kang SH, Kwak KM, Chung WK, Lee YS, Han CH, Lee EJ

  • KMID: 2293762
  • Korean J Urol.
  • 2003 Feb;44(2):198-200.
Paragangliomas are rare tumors of a neural crest origin, and belong to the amine- precursor-uptake decarboxylation (APUD) system. The great majority of paraganglioma are in the adrenal medulla. The majority...
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A Case of Multicentric Duodenal Carcinoid

Lee HK, Je SJ, Kwon SJ, Lee DY, Suh KH, Lee SM, Lee CK

  • KMID: 1929556
  • Korean J Gastrointest Endosc.
  • 1999 Feb;19(1):93-97.
Carcinoid tumors are the most common endocrine tumors of gastrointestinal tract. Argentaffin cells are the origin of carcinoids. These cells belong to the amino precursor uptake and decarboxylation (APUD) system....
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A Case of Nonfunctioning Pancreatic Islet Cell Carcinomas in Adolescence

Lee SY, Park DE, Chae KM

  • KMID: 2244247
  • Korean J Hepatobiliary Pancreat Surg.
  • 2006 Mar;10(1):41-46.
Neuroendocrine pancreatic tumors (NPTs) arise from the pancreatic islet cells and belong to the amine and precursor uptake and decarboxylation (APUD) system. These tumors are rare and account for only...
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Pyruvate Dehydrogenase Kinase as a Potential Therapeutic Target for Malignant Gliomas

Jha MK, Suk K

Metabolic aberrations in the form of altered flux through key metabolic pathways are the major hallmarks of several life-threatening malignancies including malignant gliomas. These adaptations play an important role in...
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The Effect of Agmatine on Expression of MMP2 and MMP9 in Cerebral Ischemia

Kim JH, Lee YW, Kim JY, Lee WT, Park KA, Lee JE

  • KMID: 2092923
  • Korean J Anat.
  • 2008 Mar;41(1):97-104.
Agmatine is a primary amine formed by decarboxylation of L-arginine synthesized in the mammalian brain. Recent studies have shown that agmatine is neuroprotective in models of trauma and ischemia. The...
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Pyruvate Dehydrogenase Kinases: Therapeutic Targets for Diabetes and Cancers

Jeoung NH

Impaired glucose homeostasis is one of the risk factors for causing metabolic diseases including obesity, type 2 diabetes, and cancers. In glucose metabolism, pyruvate dehydrogenase complex (PDC) mediates a major...
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Expression of Neuroendocrine Cells in the Prostate of Rat and Guinea Pig after Orchiectomy

Lee JJ, Choi HY, Lee NK

  • KMID: 2293258
  • Korean J Urol.
  • 2004 Nov;45(11):1148-1155.
PURPOSE: Neuroendocrine cells, also referred to as amine precursor uptake and decarboxylation (APUD) cells, in the prostate gland are serotonin and peptide containing cells, which are thought to play an...
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IDH Mutation Analysis in Ewing Sarcoma Family Tumors

Na KY, Noh BJ, Sung JY, Kim YW, Santini Araujo E, Park YK

BACKGROUND: Isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate to yield alpha-ketoglutarate (alpha-KG) with production of reduced nicotinamide adenine dinucleotide (NADH). Dysfunctional IDH leads to reduced production of alpha-KG...
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Agmatine Ameliorates High Glucose-Induced Neuronal Cell Senescence by Regulating the p21 and p53 Signaling

Song J, Lee B, Kang S, Oh Y, Kim E, Kim CH, Song HT, Lee JE

Neuronal senescence caused by diabetic neuropathy is considered a common complication of diabetes mellitus. Neuronal senescence leads to the secretion of pro-inflammatory cytokines, the production of reactive oxygen species, and...
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Recovered changes in the spleen by agmatine treatment after transient cerebral ischemia

Uranchimeg D, Kim JH, Kim JY, Lee WT, Park KA, Batbaatar , Tundevrentsen S, Amgalanbaatar D, Lee JE

Stroke or cerebrovascular injury is the leading cause of disability and the third leading cause of deaths worldwide. After the initial ischemic injury, sympathetic signals are transmitted to the spleen...
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