- Nickel (II)-induced apoptosis and G2/M enrichment
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Lee SH, Kim DK, Seo YR, Woo KM, Kim CS, Cho MH
- KMID: 1109301
- Exp Mol Med.
- 1998 Sep;30(3):171-176.
Treatment with certain DNA-damaging agents induce a complex cellular response comprising pertubation of cell cycle progression and/or apoptosis on proliferating mammalian cells. Our studies were focused on the cellular effects of nickel (II)... -
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- Tanshinone IIA, an ingredient of Salvia miltiorrhiza BUNGE, induces apoptosis in human leukemia cell lines through the activation of caspase-3
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Sung HJ, Choi SM, Yoon YS, An KS
- KMID: 1029923
- Exp Mol Med.
- 1999 Dec;31(4):174-178.
Tanshinone II-A is a derivative of phenanthrene-quinone isolated from Salvia miltiorrhiza BUNGE, a traditional herbal medicine that is known to induce antiinflammatory, anti-oxidative and cytotoxic activity. We have... -
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- Miltefosine-Induced Apoptotic Cell Death on Leishmania major and L. tropica Strains
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Khademvatan S, Gharavi MJ, Rahim F, Saki J
- KMID: 1715628
- Korean J Parasitol.
- 2011 Mar;49(1):17-23.
- doi: 10.3347/kjp.2011.49.1.17
The aim of this study was to assess the cytotoxic effects of various concentrations of miltefosine on Leishmania major (MRHO/IR/75/ER) and L. tropica (MHOM/IR/02/Mash10) promastigotes and to observe the programmed... -
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- IL-1beta Acts in Synergy with Endogenous IL-1beta in A375-S2 Human Melanoma Cell Apoptosis Through Mitochondrial Pathway
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Wang C, Wang MW, Tashiro SI, Onodera S, Ikejima T
- KMID: 1712732
- J Korean Med Sci.
- 2005 Aug;20(4):555-561.
- doi: 10.3346/jkms.2005.20.4.555
Interleukin-1beta (IL-1beta) is a pivotal proinflammatory cytokine. To investigate the mechanism of IL-1beta-induced cell death in human malignant melanoma A375-S2 cells, MTT assay, photomicroscopical observation, DNA agarose gel electrophoresis, radioimmunoassay... -
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- Phytotherapeutic effects of Echinacea purpurea in gamma-irradiated mice
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Abouelella AM, Shahein YE, Tawfik SS, Zahran AM
- KMID: 1106213
- J Vet Sci.
- 2007 Dec;8(4):341-351.
- doi: 10.4142/jvs.2007.8.4.341
Echinacea (E.) purpurea herb is commonly known as the purple coneflower, red sunflower and rudbeckia. In this paper, we report the curative efficacy of an Echinacea extract in gamma-irradiated mice.... -
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- Protective Effect of Ultra Low Molecular Weight Heparin on Glutamate-Induced Apoptosis in Cortical Cells
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Yu TG, Zhang QZ, Zhang ZG, Wang WW, Ji SL, Du GH
- KMID: 724266
- Yonsei Med J.
- 2008 Jun;49(3):486-495.
- doi: 10.3349/ymj.2008.49.3.486
PURPOSE: To investigate the effect of ultra low molecular weight heparin (ULMWH) on glutamate induced apoptosis in rat cortical cells and to explore the possible mechanisms. MATERIALS AND METHODS: Cell... -
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- Iron-induced cytotoxicity in cultured rat retinal neurons
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Sohn J, Yoon YH
- KMID: 1043979
- Korean J Ophthalmol.
- 1998 Dec;12(2):77-84.
- doi: 10.3341/kjo.1998.12.2.77
Oxidative stress has been proposed as a major injury mechanism in the central nervous system including the retina. In this study, as an initial attempt to study the mechanism of... -
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- Involvement of JNK-initiated p53 accumulation and phosphorylation of p53 in pseudolaric acid B induced cell death
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Gong X, Wang M, Tashiro SI, Onodera S, Ikejima T
- KMID: 1110127
- Exp Mol Med.
- 2006 Aug;38(4):428-434.
A terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL) assay was used to determine that apoptosis causes HeLa cell death induced by pseudolaric acid B. The c-Jun N-terminal kinase (JNK) inhibitor... -
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