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Application of CRISPR/Cas9 in Treating Hepatitis B Virus

Cho JY

The advent of oral antiviral agents has revolutionized hepatitis B treatment. It has led to decreased incidence and mortality related to hepatocellular carcinoma. However, although nucleos(t)ide analogs (NA) are fast...
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Occult hepatitis B virus infection: clearance or disguise?

Kim JW

No abstract available.
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Prevalence of Transfusion Transmitted Virus-Like Mini Virus in Children

Chung JY, Han TH

PURPOSE: Ttransfusion transmitted virus(TTV) is a circular DNA and consists of diverse genotypes and variants. The pathogenecity of TTV is still unclear. Recently another circular single stranded DNA virus, distantly...
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Re-engineering the mitochondrial genomes in mammalian cells

Yoon YG, Koob MD, Yoo YH

Mitochondria are subcellular organelles composed of two discrete membranes in the cytoplasm of eukaryotic cells. They have long been recognized as the generators of energy for the cell and also...
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Prevalence and Clinical Significance of TT Virus Infection in Patients on Maintenance Hemodialysis

Lee JH, Koh KC, Choi MS, Kim SJ, Lee YW, Park SJ, Lim YJ, Do JH, Lee JH, Rhee PL, Kim JJ, Paik SW, Rhee JC, Choi KW, Huh WS, Oh HY

  • KMID: 2084969
  • Korean J Gastroenterol.
  • 2001 Jan;37(1):14-20.
BACKGROUND/AIMS: TT virus (TTV) is a unenveloped, single-stranded and circular DNA virus isolated from the serum of a patient with posttransfusion hepatitis of unknown etiology. We evaluated the prevalence, risk...
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Prevalence of the TT virus viremia in Patients on Hemodialysis and General Populations

Kim EH, Cho HS, Lee CH, Kim KD

  • KMID: 2305453
  • Korean J Lab Med.
  • 2003 Apr;23(2):113-118.
BACKGROUND: The TT virus (TTV) is a recently discovered, single-stranded circular DNA virus in the serum of the patients with post-transfusion hepatitis and it is thought to be one of...
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ELISA for Quantitative Determination of Hepatitis B Virus Surface Antigen

Kim SH

Several studies have reported a good correlation between levels of serum hepatitis B virus surface antigen (HBsAg) and covalently closed circular DNA (cccDNA) before and after antiviral therapy. As a...
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Nucleotide Sequencing and Expression of Type 2 Porcine Circoviruses Isolated in Korea

Kim KM, Park HS, Kim JH, Kang SY

  • KMID: 1515657
  • J Bacteriol Virol.
  • 2003 Jun;33(2):151-160.
Porcine circovirus (PCV) is a small, nonenveloped virus that contains a single-stranded circular DNA genome of about 1.76 Kb and belongs to the family Circoviridae. The PCV-2 was thought to...
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Spontaneous HBsAg loss in Korean patients: relevance of viral genotypes, S gene mutations, and covalently closed circular DNA copy numbers

Kim KH, Chang HY, Park JY, Park ES, Park YK, Han KH, Ahn SH

BACKGROUND/AIMS: Occult HBV infection can persist following HBsAg loss and be transmitted, but the virological features are not well defined. METHODS: Here we investigated 25 Korean patients who lost HBsAg during...
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