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Effect of estrogen on the cytoskeleton of rat mammary epithelial cells in culture

Kim SH, Sung EG, Sng IH

  • KMID: 1686650
  • Korean J Anat.
  • 1993 Jun;26(2):190-198.
No abstract available.
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Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers

Kwon S, Lim HJ

The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it...
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Platelet Shape Changes and Cytoskeleton Dynamics as Novel Therapeutic Targets for Anti-Thrombotic Drugs

Shin EK, Park H, Noh JY, Lim KM, Chung JH

Platelets play an essential role in hemostasis through aggregation and adhesion to vascular injury sites but their unnecessary activation can often lead to thrombotic diseases. Upon exposure to physical or...
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The Cytoskeletal and Chromosomal Constitution in Vitrified Mouse Oocyte

Yi BK, Kim EY, Nam HK, Lee KS, Yoon SH, Park SP, Lim JH

  • KMID: 1930525
  • Korean J Fertil Steril.
  • 1998 Dec;25(3):287-292.
SUMMARY: The objective of this study was to confirm whether the vitrification method using EFS35 has detrimental effect for cytoskeleton and chromosome constitution of the mouse oocytes by indirect immunocytochemistry...
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“Hairiness” is a Facsimile of Reorganized Cytoskeletons: A Cytopathic Effect of Coxiella burnetii

Lee WY

In 1993, I reported that Coxiella burnetii transforms human B cells into hairy cells (cbHCs), the first hairy cell reported outside of hairy cell leukemia (HCL). Over last few decades,...
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Staurosporine and cytochalasin D induce chondrogenesis by regulation of actin dynamics in different way

Kim M, Song K, Jin EJ, Sonn J

  • KMID: 1389731
  • Exp Mol Med.
  • 2012 Sep;44(9):521-528.
Actin cytoskeleton has been known to control and/or be associated with chondrogenesis. Staurosporine and cytochalasin D modulate actin cytoskeleton and affect chondrogenesis. However, the underlying mechanisms for actin dynamics regulation...
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Cytochalasin B Modulates Macrophage-Mediated Inflammatory Responses

Kim MY, Kim JH, Cho JY

  • KMID: 2170622
  • Biomol Ther.
  • 2014 Jul;22(4):295-300.
The actin cytoskeleton plays an important role in macrophage-mediated inflammatory responses by modulating the activation of Src and subsequently inducing nuclear factor (NF)-kappaB translocation. In spite of its critical functions,...
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Idenfitied Differentially Expressed Genes in Keratoconus

Lee JE, Oum BS, Lee JS

  • KMID: 2210636
  • J Korean Ophthalmol Soc.
  • 2006 Dec;47(12):2012-2019.
PURPOSE: To evaluate the pathogenesis of keratoconus through differentially expressed genes in human keratocyte of keratoconus. METHODS: Total RNAs extracted from primary cultured keratocytes in normal cornea and keratoconus were used...
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Molecular association of CD98, CD29, and CD147 critically mediates monocytic U937 cell adhesion

Kim MY, Cho JY

Adhesion events of monocytes represent an important step in inflammatory responses induced by chemokines. The β1-integrin CD29 is a major adhesion molecule regulating leukocyte migration and extravasation. Although several adhesion...
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Current concepts of the podocyte in nephrotic syndrome

Ding WY, Saleem MA

  • KMID: 1441573
  • Kidney Res Clin Pract.
  • 2012 Jun;31(2):87-93.
Nephrotic syndrome is a disorder of the glomerular filtration barrier, and central to the filtration mechanism of the glomerular filtration barrier is the podocyte. We are starting to better understand...
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The Architecture of Fungal Cells

Kim DS

  • KMID: 2307107
  • Korean J Med Mycol.
  • 1998 Dec;3(2):89-94.
The Kingdom fungus has a unique structure and organization. Recent advances in electron microscopy and use of specific cytochemical technique enable the ultrastructures to be visualized. The hypha is a...
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Multiple Effects of a Novel Epothilone Analog on Cellular Processes and Signaling Pathways Regulated by Rac1 GTPase in the Human Breast Cancer Cells

Zhang H, An F, Tang L, Qiu R

The epothilones are a class of microtubule inhibitors that exhibit a strong antitumor activity. UTD2 is a novel epothilone analog generated by genetic manipulation of the polyketide biosynthetic gene cluster....
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L-plastin: Structure, Regulation, and Roles in Cancer Invasion and in Macrophages

Kim HJ, Lee HH

The cytoskeleton consists of 3 filamentous components: intermediate filaments, microtubules, and actin filaments. Actin filaments continuously assemble and disassemble far out of equilibrium to adapt cells in response to external...
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Cross-linking of CD4 induces cytoskeletal association of CD4 and p56lck

Ha-Lee YM, Lee YS, Kim YK, Sohn JW

  • KMID: 927129
  • Exp Mol Med.
  • 2000 Mar;32(1):18-22.
A membrane glycoprotein CD4 functions as a co-receptor of a T lymphocyte. The co-receptor function has been attributed to a protein tyrosine kinase, p56lck, which is activated upon CD4 binding...
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Screening and Selection of Proteins Interacting with Myocilin

Cho MK, Son SS, Kee CW

  • KMID: 2337332
  • J Korean Ophthalmol Soc.
  • 2006 Apr;47(4):637-642.
PURPOSE: To identify novel proteins which bind to myocilin, using a yeast two-hybrid screening system. METHODS: A bait plasmid of myocilin was constructed, and then transformed into yeast AH109. The transformed...
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Distribution of Cytokeratins in Cholesteatomas according to the Induction Period of Cholesteatoma in Gerbil

Kim CS, Chung JW, Choi SH

  • KMID: 2274276
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Jan;40(1):76-81.
The exact pathogenesis of aural cholesteatoma is not yet fully understood in spite of many studies. Animal models are very important in studying the pathogenesis of aural cholesteatoma because such...
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Expression of E-cadherin and a-catenin in Thyroid Carcinomas

Kim SJ, Lee MC

  • KMID: 2331080
  • J Korean Soc Endocrinol.
  • 1997 Dec;12(4):533-540.
BACKGROUND: Cell-cell adhesion in tissue is mainly regulated by hornotypic interaction of cadherin molecules, which are anchored to the cytoskeleton via cytoplasmic proteins, including a-and / 3-catenin. Loss of E-cadherin...
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Genetic Basis of Steroid Resistant Nephrotic Syndrome

Park E

Steroid-resistant nephrotic syndrome (SRNS) has long been a challenge for clinicians due to its poor responsiveness to immunosuppressants, and rapid progression to end-stage renal disease. Identifying a monogenic cause for...
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The Effect of Cytochalasin B on Cytoskeletal Stability of Mouse Oocyte Frozen by Vitrification

Paik WY, Choi WJ, Kim SN, Lee JH

  • KMID: 1566318
  • Korean J Fertil Steril.
  • 2002 Dec;29(4):229-236.
OBJECTIVE: The purpose of this study was to evaluate the effect of Cytochalasin B (CCB) on the cytoskeletal stability of mouse oocyte frozen by vitrification. METHODS: Mouse oocytes retrieved from cycle...
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CD98 activation increases surface expression and clusteringof beta 1 integrins in MCF-7 cells through FAK/Src- and cytoskeleton-independent mechanisms

Kim SM, Hahn JH

CD98, a disulfide-linked 125-kDa heterodimeric type II transmembrane glycoprotein, regulates beta 1 integrin- mediated cell adhesion. However, the molecular mechanisms underlying CD98-mediated activation of beta 1 integrin are presently unclear....
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