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The Effect of BHA and BHT on Mixed Function Oxygenase of Liver Tissue

Sung NE

To evaluate the effect of BHA and BHT on liver tissue, BHA and BHT, 100mg and 200mg/kg B.W. respectively, were given to experimental animals for 4 months. Microsomal cytochrome P-450, cytochrome...
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Molecular Characterization of Hard Ticks by Cytochrome c Oxidase Subunit 1 Sequences

Gou H, Xue H, Yin H, Luo J, Sun X

Although widely studied, the natural diversity of the hard tick is not well known. In this study, we collected 194 sequences from 67 species, covering 7 genera of hard tick....
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Pro-apoptotic Cytochrome c Gene Mutation is Rare in Non-small Cell Lung Cancers

Soung YH, Lee SH

PURPOSE: Several lines of evidence have indicated that the deregulation of apoptosis is involved in the mechanisms of cancer development, and somatic mutations of the apoptosis-related genes have been reported...
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The Expression of Bcl-2, Bax, Cytochrome C and Caspase-3 in Camptothecin-Induced Apoptosis of Mouse 3T3 Fibroblasts

Ahn YJ, Lee MS, Kang G

  • KMID: 2073723
  • Korean J Pathol.
  • 2002 Apr;36(2):71-76.
BACKGROUND: Camptothecin (CPT), which has been used for cancer treatment and apoptosis as an inhibitor of DNA topoisomerase I. We investigated the possibility that camptothecin induces anti-appoptotic bcl-2 and pro-apoptotic...
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Molecular characterization of Plasmodium juxtanucleare in Thai native fowls based on partial cytochrome C oxidase subunit I gene

Pohuang T, Junnu S

Avian malaria is one of the most important general blood parasites of poultry in Southeast Asia. Plasmodium (P.) juxtanucleare causes avian malaria in wild and domestic fowl. This study aimed...
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Superoxide Anion Generation of Neutrophils in Patients with Atopic Dermatitis

Yeo UC, Kim SH

  • KMID: 1920688
  • Korean J Dermatol.
  • 1990 Dec;28(6):669-676.
Atopic dermatitis is characterized by many signs of immunodeficiency. We have performed this experiment to know whether there are reduced respiratoty burst of neutrophils in patients with atopic dermatitis in...
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The Effect of Cytochrome C in Ophthalmic Diseases

Kim HC, Kim JJ, Pak BG

  • KMID: 1675861
  • J Korean Ophthalmol Soc.
  • 1968 Mar;9(1):1-8.
Cytochrome compounds which act as electron transfer agents in oxidation-reduction reactions. An important example is cytochrome c, which has a molecular weight of about 13,000 and contains one atom of...
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Cytochrome C Oxidase Subunit 1, Internal Transcribed Spacer 1, Nicotinamide Adenine Dinucleotide Hydrogen Dehydrogenase Subunits 2 and 5 of Clonorchis sinensis Ancient DNA Retrieved from Joseon Dynasty Mummy Specimens

Hong JH, Oh CS, Chai JY, Seo M, Shin DH

We analyzed Clonorchis sinensis ancient DNA (aDNA) acquired from the specimens of the Joseon mummies. The target regions were cytochrome C oxidase subunit 1 (CO1), internal transcribed spacer 1 (ITS1),...
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A Study of Apoptosis Induced by Microinjection of Cytochrome c Protein into Mouse 3T3 Fibroblast

Lee MS, Kang G

  • KMID: 2275573
  • Korean J Pathol.
  • 2002 Feb;36(1):1-6.
BACKGROUND: Microinjectors have been used for cell biology and development, and are useful for the study of cellular morphologic changes with response to the external milieu and intracellularly injected molecules....
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Inhibiting Cytochrome C Oxidase Leads to Alleviated Ischemia Reperfusion Injury

Yang Z, Duan Z, Yu T, Xu J, Liu L

BACKGROUND AND OBJECTIVES: The overall purpose of this study was to investigate the role of cytochrome C oxidase (CcO) in preventing ischemia reperfusion-induced cardiac injury through gaseous signaling molecule pathways. MATERIALS...
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The changes of mitochondrial cytochrome c and GABAergic neuron in neuropathic pain model

Kim WS, Park JY, Kim TK, Baik SW

BACKGROUND: Role of cytochrome c (Cyt c) is an apoptogenic agent under certain conditions. The mitochondrial permeability transition pore (MPTP) plays an important role in cell death since it opens,...
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The Expression of Cytochrome c, TNF-R1 and Fas Ligand in Patient's Serum after Successful Cardiopulmonary Resuscitation

So BH, Youn CS, Jeong SK, Choi SP, Kim HM, Park KN

  • KMID: 2332706
  • J Korean Soc Emerg Med.
  • 2010 Apr;21(2):147-155.
PURPOSE: Numerous reports have suggested that apoptosis may play an important role in postresuscitation syndrome. The aim of this study is to assess the levels of molecules that are associated...
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A study on the Effects of Hyperbaric Oxygenation Combined with the Drug Administration in the Treatment of CO poisoning

Youn DR, Kim IS

  • KMID: 2281881
  • Korean J Prev Med.
  • 1973 Dec;6(1):71-76.
1)The oxygen consumption was studied with albino rate under normal environment after they were given Cytochrome C intravenously (10mg/kg). The consumption was 74.6cc/kg min. with that of control, 75.4cc/kg. min....
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Dimethoxycurcumin, a Structural Analogue of Curcumin, Induces Apoptosis in Human Renal Carcinoma Caki Cells Through the Production of Reactive Oxygen Species, the Release of Cytochrome c, and the Activation of Caspase-3

Lee JW, Hong HM, Kwon DD, Pae HO, Jeong HJ

  • KMID: 2314590
  • Korean J Urol.
  • 2010 Dec;51(12):870-878.
PURPOSE: Curcumin (Cur) has been reported to induce apoptosis in human renal carcinoma Caki cells. Dimethoxycurcumin (DMC), one of several synthetic Cur analogues, has been reported to have increased metabolic...
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Cytotoxic Activity from Curcuma zedoaria Through Mitochondrial Activation on Ovarian Cancer Cells

Shin Y, Lee Y

  • KMID: 2317844
  • Toxicol Res.
  • 2013 Dec;29(4):257-261.
alpha-Curcumene is one of the physiologically active components of Curcuma zedoaria, which is believed to perform anti-tumor activities, the mechanisms of which are poorly understood. In the present study, we...
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Paraquat Induces Apoptosis through Cytochrome C Release and ERK Activation

Seo HJ, Choi SJ, Lee JH

Paraquat has been suggested to induce apoptosis by generation of reactive oxygen species (ROS). However, little is known about the mechanism of paraquat-induced apoptosis. Here, we demonstrate that extracellular signal-regulated...
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Effect of UV Irradiation on Superoxide Dismutase Activities of the Rabbit Skin

Lee SC, Chun IK, Kim YP

  • KMID: 2231469
  • Korean J Dermatol.
  • 1987 Aug;25(4):441-445.
This study was undertaken to know whether the UV-irradiation of the skin causes changes in the superoxide dismutase(SOD) activities. After shaving, the back skin of the rabbit was irradiated with...
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The Apoptosis induced by Ceramide and Phytoceramide in the Lens Epithelial Cell

Chae JB, Kim TI, Tchah H

  • KMID: 2337121
  • J Korean Ophthalmol Soc.
  • 2003 Nov;44(11):2627-2636.
PURPOSE: The purpose of this study was to determine if ceramide, which is known as secondary messenger of programmed cell death (apoptosis), can cause apoptosis in lens epithelial cell (LEC)...
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Diallyl Disulfide Inhibits Cytochrome c-Mediated Apoptosis in H2O2 Induced Death of Neuronal-differentiated PC12 Cells

Koh SH, Kwon H, Park Y, Kim JG, Kim K, Song CW, Kim JH, Kim J, Kim MH, Kim KS, Yu HJ, Jung HK, Kim SH

  • KMID: 2343087
  • J Korean Neurol Assoc.
  • 2004 Aug;22(4):375-381.
BACKGROUND: The effects of diallyl disulfide (DADS), a garlic derived compound, on the viability and cell signaling- like the downstream signaling through cytochrome c, caspase-3, poly (ADP-ribose) polymerase (PARP) during...
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Effect of High Glucose on the Production of Reactive Oxygen Species in R28 Cells

Lee JM, Kim JW

  • KMID: 2425092
  • J Korean Ophthalmol Soc.
  • 2010 May;51(5):746-750.
PURPOSE: To investigate the effect of high glucose (HG) on the production of reactive oxygen species (ROS) in retinal precursor R28 cells. METHODS: R28 cells were incubated with low glucose (5...
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