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Cyclins and Cancer

Park SS, Lee JH

  • KMID: 2317891
  • Tuberc Respir Dis.
  • 1995 Apr;42(2):123-129.
No abstract available.
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Effect of Gl Cyclins Expression on Clinical Prognostic Parameters in Cervical Carcinoma

Kim YT, Choe BH, Kim JW, Ko JH, Choi EK

  • KMID: 1537006
  • Korean J Gynecol Oncol Colposc.
  • 1999 Sep;10(3):233-241.
Alterations in the expression of genes that control the cell cycle may be of critical importance in tumorigenesis and malignant transformation. The major regulatory events leading to cell proliferation occur...
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Correlation between G1 Cyclins Expression and Clinical Prognostic Parameters in Endometrial Carcinoma

Kim YT, Kim SH, Kim JW, Lee JW, Park KH

  • KMID: 1615588
  • Korean J Gynecol Oncol Colposc.
  • 2003 Mar;14(1):30-39.
OBJECTIVE: Cyclins D1 and E play important roles in the progression of cell through G1 phase of the cell cycle. Amplification and/or overexpression of the cyclin D1 gene and aberrant...
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Cyclin Dependent Kinase Inhibitors (CDKIs) and Genetic Alterations of CDKN2 (p16-INK4A/MTS1) Gene in Hematologic Malignancies

Yang CH

  • KMID: 2335249
  • J Korean Pediatr Soc.
  • 1997 May;40(5):593-599.
No abstract available.
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CYCLIN D1 as a Genetic Modifier in Hereditary Nonpolyposis Colorectal Cancer

Kim WH

  • KMID: 1599443
  • Korean J Gastroenterol.
  • 2001 Nov;38(5):397-398.
No abstract available.
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Significance of Expression of bcl-2, p53 and cyclin D1 and Their Correlation with Clinicopathologic Prognostic Factors and Survival Rate in 128 Cases of Invasive Breast Carcinoma

Park SH, Lee MJ, Jeon HJ

  • KMID: 1568981
  • Korean J Obstet Gynecol.
  • 2000 Aug;43(8):1360-1367.
No abstract available.
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CHANGES OF CYCLINS, CYCLIN DEPENDENT KINASES, CYCLIN DEPENDENT KINASE INHIBITORS DURING GLOSSAL DEVELOPMENT IN THE RATS

Kim HH, Lee SC

  • KMID: 2005912
  • J Korean Assoc Oral Maxillofac Surg.
  • 1997 Nov;23(4):581-596.
The molecular mechanisms that regulate glossal muscle cell cycle and terminal differentiation remain largely unknown. To determine which cyclins, cyclin dependent kinases (CDKs), cyclin dependent kinase inhibitors (CKIs) are important...
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Reduced Expression of Cyclins and Proliferative Indices on the Psoriatic Epidermis after 12 Weeks of Oral Cyclosporin Therapy

Han SS, Hyun OS, Chang SE, Lee MW, Choi JH, Moon KC, Koh JK

Cell growth characterized by cell cycle progression is regulated by cyclin-dependent kinase (CDK). CDKs are activated by binding cyclins such as cyclin A, cyclin B, cyclin D1, and cyclin E....
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Expression of the D1 and E Cyclins in Carcinoma of the Cervix

Kim YT, Lee JW, Kim JU, Cho NH

  • KMID: 2269558
  • Korean J Obstet Gynecol.
  • 1998 Jun;41(6):1545-1551.
Multiple genetic changes occur during the evolution of normal cells into cancer cells. Recent work has identified another category of genes that, when mutated, increase genetic instability and accelerate cellular...
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Expression of Cyclin A, B1, D1, D3, and E in Non-Small Lung Cancers

Ha SY, Kim HK, Im JS, Cho HY, Chung DH, An J

PURPOSE: Cyclins, and their associated cyclin dependent kinases, regulate progression of the cell cycle through the G1 phase and into the S-phase during the DNA replication process. Cyclin E regulation...
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Expression of Cyclins (D1, A, E, and B1) in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced Rat Bladder Carcinogenesis

Kwon GY, Park ES, Bong SG, Lee TJ, Kim MK, Yoo JH, Song KY

  • KMID: 2011752
  • Korean J Pathol.
  • 2003 Aug;37(4):255-262.
BACKGROUND: Cell cycle deregulation plays a major role in chemical multistage carcinogenesis.Therefore, the evaluation of cell cycle proteins is important. METHODS: In order to induce carcinogenesis in the rat urinary...
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Cell cycle regulators during human atrial development

Kim WH, Joo CU, Ku JH, Ryu CH, Koh KN, Koh GY, Ko JK

  • KMID: 759076
  • Korean J Intern Med.
  • 1998 Jul;13(2):77-82.
OBJECTIVES: The molecular mechanisms that regulate cardiomyocyte cell cycle and terminal differentiation in humans remain largely unknown. To determine which cyclins, cyclin dependent kinases (CDKs) and cyclin kinase inhibitors (CKIs)...
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Changes in expression of cell cycle regulators and their hepatic lobular distribution in partial hepatectomy-induced regenerating rat liver

Jeong JS, Lee JH, Kim HI, Park JI

Partial hepatectomy (PH) endorses quiescent hepatocytes to reenter the cell cycle. The regenerating liver returns to its preresection weight after 7 days, following one or two cell division and maintains...
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Cell Cycle Signaling Pathway by Cyclins-CDKs and CDKIs in Endometriosis

Jeong KA, Park KH, Yoon HS, Yoon JM, Sohn WH, Bai SW, Kim YT, Lee BS, Seo K, Kim SK, Cho DJ, Song CH

  • KMID: 2272274
  • Korean J Obstet Gynecol.
  • 2004 Feb;47(2):307-312.
OBJECTIVE: This study was undertaken to evaluate the cell cycle signaling pathway by cyclins-cyclin dependent kinases (CDKs) and cyclin dependent kinase inhibitors (CDKIs) in endometriosis. METHODS: 38 women with endometriosis were...
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Expression of cyclins in ductal hyperplasia, atypical ductal hyperplasia and ductal carcinoma in situ of the breast

Kim HJ, Jung WH, Kim DY, Lee HD

Cyclin/cdc complexes are known to function in cell-cycle regulation. Cyclin D1/cdk4 and -6 complexes, which functions as a G1-S checkpoint and cyclin B1/cdc2 complexes, a G2-M checkpoint are essential for...
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Expression of Cyclin A and Ki-67 in the Uterine Cervical Carcinoma

Kim MK, Bae DH, Kim CJ

  • KMID: 2244993
  • Korean J Gynecol Oncol Colposc.
  • 1998 Dec;9(4):464-470.
The cell cycle is the set of events that is responsible for the duplication of the cells. Recent studies indicate that cell cycle regulatory proteins, mainly the cyclins and cyclin-related...
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Expression of cyclin E in gestational trophoblastic disease

Yi JW, Kim YT, Kim JW, Kim SH, Kim DK

  • KMID: 2143479
  • Korean J Gynecol Oncol Colposc.
  • 2002 Mar;13(1):38-48.
Gestational trophoblastic disease represents a spectrum of lesions characterized by an abnormal proliferation of trophoblast, including partial mole, complete mole, invasive mole, choriocarcinoma, and placental site trophoblastic tumor, which have...
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Cyclin B1 and D1 expression in invasive cervical cancer

Kim YT, Zhao M, Kim HY, Kang MH, Kim JW, Kim SH, Kim JH, Kim SW, Yoon BS

  • KMID: 1575056
  • Korean J Gynecol Oncol.
  • 2005 Sep;16(3):256-263.
OBJECTIVE: Cyclin is a family of regulatory proteins that play a key role in controlling the cell cycle. Abnormalities of cell cycle regulators, including cyclins and cyclin dependent kinases (CDKs),...
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Expressions of Cyclin E-pathway Proteins (cyclinE, cdk2, p21, p27, p57) and Their Prognostic Significance in Non-small Cell Lung Carcinomas

Jung JH, Park G, Lee MA, Byun JH, Jung CK, Lee H, Lee KY, Shim SI, Kang CS

  • KMID: 1593157
  • Korean J Pathol.
  • 2006 Feb;40(1):24-31.
BACKGROUND: The aberrant expression of cyclins, cdk and cdk inhibitor has been shown to be involved in oncogenic transformation. The aim of this study was to investigate the expression of...
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Tannic acid-induced apoptosis in FaDu hypopharyngeal squamous cell carcinoma

Ta LT, Nguyen TT, Yoo H

Tannic acid (TA) is a water-soluble polyphenol compound found in various herbal plants. We investigated the chemopreventive effects of TA on FaDu hypopharyngeal squamous carcinoma cells. In an 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide...
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