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Cancer Epigenetics

Chang DK

  • KMID: 1113291
  • Korean J Gastroenterol.
  • 2004 Jul;44(1):1-12.
Knowledge regarding molecular events of cancer development has been rapidly accumulated during the last decade. The discovery of tumor suppressor gene-silencing by aberrant promoter CpG island hypermethylation and histone-directed chromatin...
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Lack of Aberrant Methylation in an Adjacent Area of Left-Sided Colorectal Cancer

Sambuudash O, Kim HS, Cho MY

PURPOSE: The molecular nature and the rate-limiting step of epigenetic field defects in the evolution of left-sided colorectal cancer (LCA) remain uncertain. MATERIALS AND METHODS: The methylation status of 27 candidate...
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Biomarkers for Colorectal Cancer Treatment

Suk KT, Kim HS

  • KMID: 1062808
  • Korean J Gastroenterol.
  • 2009 Feb;53(2):68-75.
Individualized tailored therapy is a currently pursuing direction for improving the outcome of patients with colorectal cancer. Targeted therapy is the potential strategy to reach this goal by evaluating status...
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