- Functional Role of a Conserved Sequence Motif in the Oxygen-dependent Degradation Domain of Hypoxia-inducible Factor 1 alpha in the Recognition of p53
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Chi SW
- KMID: 2166342
- Genomics Inform.
- 2008 Jun;6(2):72-76.
Hypoxia-inducible factor 1 alpha (HIF1 alpha) is a transcription factor that plays a key role in the adaptation of cells to low oxygen stress and oxygen homeostasis. The oxygen-dependent degradation... -
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- Aspartic proteases of Plasmodium vivax are highly conserved in wild isolates
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Na BK, Lee EG, Lee HW, Cho SH, Bae YA, Kong Y, Lee JK, Kim TS
- KMID: 1051420
- Korean J Parasitol.
- 2004 Jun;42(2):61-66.
- doi: 10.3347/kjp.2004.42.2.61
The plasmepsins are the aspartic proteases of malaria parasites. Treatment of aspartic protease inhibitor inhibits hemoglobin hydrolysis and blocks the parasite development in vitro suggesting that these proteases might be... -
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- Synthetic and Adenovirus Delivered Small Interference RNA Pools Targeting Conserved Regions of Foot-and-Mouth Disease Virus
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Kim SM, Lee KN, Ko YJ, Joo YS, Kim HS, Park JH
- KMID: 2168584
- J Bacteriol Virol.
- 2010 Dec;40(4):199-206.
- doi: 10.4167/jbv.2010.40.4.199
Foot-and-mouth disease (FMD) is an economically significant animal disease because of the speed of its transmission. Routine vaccination may not be effective for early protection in an outbreak situation. Small... -
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- Genetic characterization of porcine circovirus-2 field isolates from PMWS pigs
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Kim JH, Lyoo YS
- KMID: 1101572
- J Vet Sci.
- 2002 Mar;3(1):31-39.
PMWS is a new emerging disease in swine herds worldwide. Field isolates of PCV-2, a putative major causative agent of PMWS, were isolated and genetically characterized. Viral genome of two... -
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- RNA polymerase II carboxy-terminal domain with multiple connections
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Cho EJ
- KMID: 1047075
- Exp Mol Med.
- 2007 Jun;39(3):247-254.
The largest subunit of eukaryotic RNA polymerase II contains a unique domain at its carboxy-terminus, which is referred to as the carboxy-terminal domain (CTD). The CTD is made up of... -
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- Molecular phylogeny of parasitic Platyhelminthes based on sequences of partial 28S rDNA D1 and mitochondrial cytochrome c oxidase subunit I
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Lee SU, Chun HC, Huh S
- KMID: 1104528
- Korean J Parasitol.
- 2007 Sep;45(3):181-189.
- doi: 10.3347/kjp.2007.45.3.181
The phylogenic relationships existing among 14 parasitic Platyhelminthes in the Republic of Korea were investigated via the use of the partial 28S ribosomal DNA (rDNA) D1 region and the partial... -
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- Heterogeneous HBV mutants coexist in Korean hepatitis B patients
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Keum WK, Kim JY, Kim JY, Chi SG, Hong JW, Kim SS, Ha JH, Kang IS
- KMID: 754997
- Exp Mol Med.
- 1998 Jun;30(2):115-122.
Although many hepatitis B virus (HBV) mutants have been found in all open reading frames since the precore defective mutant was initially reported, systematic investigations of diverse HBV mutant populations in hepatitis... -
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- Identification and Molecular Characterization of Parkin in Clonorchis sinensis
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Bai X, Kim TI, Lee JY, Dai F, Hong SJ
- KMID: 2381798
- Korean J Parasitol.
- 2015 Feb;53(1):65-75.
- doi: 10.3347/kjp.2015.53.1.65
Clonorchis sinensis habitating in the bile duct of mammals causes clonorchiasis endemic in East Asian countries. Parkin is a RING-between-RING protein and has E3-ubiquitin ligase activity catalyzing ubiquitination and degradation... -
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- Genomic Analysis of miR-21-3p and Expression Pattern with Target Gene in Olive Flounder
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Jo A, Lee HE, Kim HS
- KMID: 2394766
- Genomics Inform.
- 2017 Sep;15(3):98-107.
- doi: 10.5808/GI.2017.15.3.98
MicroRNAs (miRNAs) act as regulators of gene expression by binding to the 3’ untranslated region (UTR) of target genes. They perform important biological functions in the various species. Among many... -
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- Conjugation and deconjugation of ubiquitin regulating the destiny of proteins
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Baek KH
- KMID: 1088651
- Exp Mol Med.
- 2003 Feb;35(1):1-7.
The homeostasis for a number of cellular proteins is regulated by not only phosphorylation and dephosphorylation, but also ubiquitination and deubiquitination. A number of proteins involved in the degradation of... -
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- Gene Cloning, Expression and Immunogenicity of the Protective Antigen Subolesin in Dermacentor silvarum
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Hu Y, Zeng H, Zhang J, Wang D, Li D, Zhang T, Yang S, Liu J
- KMID: 1715679
- Korean J Parasitol.
- 2014 Feb;52(1):93-97.
- doi: 10.3347/kjp.2014.52.1.93
Subolesin (4D8), the ortholog of insect akirins, is a highly conserved protective antigen and thus has the potential for development of a broad-spectrum vaccine against ticks and mosquitoes. To date,... -
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- Molecular Identification and Distribution of Aquaporins in Human and Rat Testes
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Park NC, Park YS, Jung JS
- KMID: 2085128
- Korean J Fertil Steril.
- 2000 Jun;27(2):133-144.
OBJECTIVE: Several water channels (aquapoins; AQP) that belong to the MIP (major intrinsic protein) family have identified. In the selected tissues including red blood cells or renal tubules, water movements... -
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- Cloning and characterization of 5'-upstream region of human phospholipase C-beta2 gene
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Yun ES, Lee SJ, Kim MJ, Ryu SH, Suh PG
- KMID: 1085743
- Exp Mol Med.
- 2001 Jun;33(2):76-82.
5'-upstream region of the phospholipase C-beta2 gene, 810 bp, was cloned and characterized. S1 nuclease mapping and primer extension analyses revealed that a single transcriptional start site locates at 284... -
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- Detection of Astrovirus Infection from Hospitalized Young Children Feces by Reverse Transcription - Polymerase Chain Reaction
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Park HK, Woo SY, Seoh JY, Chong YH, Seo JW
- KMID: 1543608
- J Korean Soc Microbiol.
- 1999 Oct;34(5):453-459.
Astrovirus is frequently associated with diarrhea in children. It can not be readily isolated by cell culture, and an electronmicroscope is usually used for detection of this agent. Recently in... -
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- Expression and Cellular Localization of Psx Gene in Rat Placenta
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Choi EH, Jung C, Nam KI, Lee SW, Bae CS, Kim BY, Park SS, Ahn KY
- KMID: 1982474
- Korean J Phys Anthropol.
- 2011 Mar;24(1):51-56.
Homeobox genes seem to play critical roles in regulating morphogenesis, patterning, organogenesis, and differentiation. They have the conserved sequence that codes the DNA-binding domain called homeodomain. The expression and cellular... -
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- Genomic organization and expression of parkin in Drosophila melanogaster
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Bae YJ, Park KS, Kang SJ
- KMID: 1093612
- Exp Mol Med.
- 2003 Oct;35(5):393-402.
We report here the isolation, characterization on genomic structure and expression of the D. melanogaster homolog of human parkin. The 2,122 bp parkin gene sequence contains six exons that form... -
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- Isolation of MLL1 Inhibitory RNA Aptamers
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Ul-Haq A, Jin ML, Jeong KW, Kim HM, Chun KH
- KMID: 2442012
- Biomol Ther.
- 2019 Feb;27(2):201-209.
- doi: 10.4062/biomolther.2018.157
Mixed lineage leukemia proteins (MLL) are the key histone lysine methyltransferases that regulate expression of diverse genes. Aberrant activation of MLL promotes leukemia as well as solid tumors in humans,... -
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- Molecular Cloning of Plasmodium vivax Calcium-Dependent Protein Kinase 4
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Choi KM, Kim JY, Moon SU, Lee HW, Sattabongkot J, Na BK, Kim DW, Suh EJ, Kim YJ, Cho SH, Lee HS, Rhie HG, Kim TS
- KMID: 1104699
- Korean J Parasitol.
- 2010 Dec;48(4):319-324.
- doi: 10.3347/kjp.2010.48.4.319
A family of calcium-dependent protein kinases (CDPKs) is a unique enzyme which plays crucial roles in intracellular calcium signaling in plants, algae, and protozoa. CDPKs of malaria parasites are known... -
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- A Novel Mismatched PCR-Restriction Fragment Length Polymorphism Assay for Rapid Detection of gyrA and parC Mutations Associated With Fluoroquinolone Resistance in Acinetobacter baumannii
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Kakuta N, Nakano R, Nakano A, Suzuki Y, Tanouchi A, Masui T, Horiuchi S, Endo S, Kakuta R, Ono Y, Yano H
- KMID: 2457490
- Ann Lab Med.
- 2020 Jan;40(1):27-32.
- doi: 10.3343/alm.2020.40.1.27
BACKGROUND: Mutations in the quinolone resistance-determining regions (QRDRs) of Acinetobacter baumannii DNA gyrase (gyrA) and topoisomerase IV (parC) are linked to fluoroquinolone (FQ) resistance. We developed a mismatched PCR-restriction fragment... -
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- Simultaneous Detection and Identification of Human Respiratory Syncytial Virus, Influenza Virus A ( H3N2 , H1N1 ) and B by One - tube Multiplex Reverse Transcription Polymerase Chain Reaction
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Park YH, Woo YD, Kim SK, Bae HJ, Park SW
- KMID: 1571509
- J Bacteriol Virol.
- 2001 Sep;31(3):269-274.
Respiratory syncytial virus (RSV) and Influenza virus are the most common pathogen for causing severe upper respiratory infection in all age groups. A multiplex reverse transcription polymerase chain reaction (RT-PCR)... -
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