- Synergistic effect of peroxiredoxin II antisense on cisplatin-induced cell death
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Yoo YD, Chung YM, Park JK, Ahn CM, Kim SK, Kim HJ
- KMID: 931877
- Exp Mol Med.
- 2002 Sep;34(4):273-277.
Peroxiredoxin II (Prx II) is known not only to protect cells from oxidative damage caused by hydrogen peroxide (H2O2), but also to endow cancer cells with resistance to both... -
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- 2,3,7,8-Tetrachlorodibenzo-P-Dioxin Induced Cell-Specific Drug Transporters With Acquired Cisplatin Resistance in Cisplatin Sensitive Cancer Cells
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Gotovdorj , Lee E, Lim Y, Cha EJ, Kwon D, Hong E, Kim Y, Oh MY
- KMID: 1794595
- J Korean Med Sci.
- 2014 Sep;29(9):1188-1198.
- doi: 10.3346/jkms.2014.29.9.1188
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) can induce drug transporter genes such as the ATP-binding cassette G member 2 (ABCG2), which contributes to multidrug resistance. We investigated the effect of TCDD pretreatment on drug... -
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- Change of the Expression of Human Telomerase Reverse Transcriptase mRNA and Human Telomerase RNA after Cisplatin and 5-Fluorouracil Exposure in Head and Neck Squamous Cell Carcinoma Cell Lines
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Lee BJ, Lee BH, Wang SG, Lee JC, Roh HJ, Goh EK, Kim CM, Jun ES
- KMID: 1785792
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S73-S78.
- doi: 10.3346/jkms.2007.22.S.S73
Telomerase activity appears to be associated with cell immortalization and malignant progression. Understanding how telomerase activity is regulated in vivo is important not only for understanding the molecular biology of... -
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- Upregulated expression of BCL2, MCM7, and CCNE1 indicate cisplatin-resistance in the set of two human bladder cancer cell lines: T24 cisplatin sensitive and T24R2 cisplatin resistant bladder cancer cell lines
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Kim SH, Ho JN, Jin H, Lee SC, Lee SE, Hong SK, Lee JW, Lee ES, Byun SS
- KMID: 2363126
- Investig Clin Urol.
- 2016 Jan;57(1):63-72.
- doi: 10.4111/icu.2016.57.1.63
PURPOSE: The mechanism of resistance to cisplatin during treatment of bladder cancer (BC) has been a subject of intense investigation in clinical research. This study aims to identify candidate genes... -
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- Human Telomerase Reverse Transcriptase (hTERT): A Target Molecule for the Treatment of Cisplatin-resistant Tumors
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Park YP, Kim KD, Kang SH, Yoon DY, Park JW, Kim JW, Lee HG
- KMID: 1781577
- Korean J Lab Med.
- 2008 Dec;28(6):430-437.
- doi: 10.3343/kjlm.2008.28.6.430
BACKGROUND: Human telomerase reverse transcriptase (hTERT) is a catalytic enzyme that is required for telomerase activity (TA) and cancer progression. Telomerase inhibition or inactivation increases cellular sensitivity to UV irradiation,... -
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- Human hepatocellular carcinoma cells resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin
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Shin EC, Seong YR, Kim CH, Kim H, Ahn YS, Kim K, Kim SJ, Hong SS, Park JH
- KMID: 1081460
- Exp Mol Med.
- 2002 May;34(2):114-122.
TNF-related apoptosis-inducing ligand (TRAIL), a member of the TNF family, selectively induce apoptosis in various transformed cell lines but not in almost-normal tissues. It is regulated by 2 death receptors,... -
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