- Polymorphonuclear leukocyte functions enhanced by chemotaxis
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Hong YS
- KMID: 1421931
- J Korean Med Sci.
- 1992 Dec;7(4):307-313.
- doi: 10.3346/jkms.1992.7.4.307
Human polymorphonuclear leukocytes (PMN) migrate into tissues in response to chemoattractants, yet it is not known whether this process alters the functional capabilities of the PMN. Using recombinant human... -
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- The synthetic peptide, His-Phe-Tyr-Leu-Pro-Met, is a chemoattractant for Jukat T cells
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Kim YD, Bae YS, Park JC, Suh PG, Ryu SH
- KMID: 1457539
- Exp Mol Med.
- 2001 Dec;33(4):257-262.
His-Phe-Tyr-Leu-Pro-Met (HFYLPM) is a synthetic peptide that stimulates Jurkat T cells resulting in intracellular calcium ([Ca2+]i) increase in a pertussis toxin (PTX)-sensitive manner. We have examined the physiological role of... -
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- Lysophosphatidylglycerol inhibits formyl peptide receptor like-1-stimulated chemotactic migration and IL-1beta production from human phagocytes
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Shim JW, Jo SH, Kim SD, Lee HY, Yun J, Bae YS
- KMID: 1119324
- Exp Mol Med.
- 2009 Aug;41(8):584-591.
- doi: 10.3858/emm.2009.41.8.064
In this study, we observed that lysophosphatidylglycerol (LPG) completely inhibited a formyl peptide receptor like-1 (FPRL1) agonist (MMK-1)-stimulated chemotactic migration in human phagocytes, such as neutrophils and monocytes. LPG also... -
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- Identification of novel peptides that stimulate human neutrophils
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Bae GH, Lee HY, Jung YS, Shim JW, Kim SD, Baek SH, Kwon JY, Park JS, Bae YS
- KMID: 1120131
- Exp Mol Med.
- 2012 Feb;44(2):130-137.
- doi: 10.3858/emm.2012.44.2.008
Neutrophils play a key role in innate immunity, and the identification of new stimuli that stimulate neutrophil activity is a very important issue. In this study, we identified three novel... -
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- p38 MAPK and ERK activation by 9-cis-retinoic acid induces chemokine receptors CCR1 and CCR2 expression in human monocytic THP-1 cells
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Ko J, Yun CY, Lee JS, Kim JH, Kim IS
- KMID: 1094653
- Exp Mol Med.
- 2007 Apr;39(2):129-138.
9-cis-retinoic acid (9CRA) plays an important role in the immune response; this includes cytokine production and cell migration. We have previously demonstrated that 9CRA increases expression of chemokine receptors CCR1... -
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- Inhibitory Effect of Inducible Nitric Oxide Synthase Gene Transfer on Intimal Hyperplasia and Fibronectin Expression Induced by Carotid Artery Denudation
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Kye BH, Hong SY, Yang KH, Park SC, Park JS
- KMID: 1941030
- J Korean Soc Vasc Surg.
- 2004 Dec;20(2):192-199.
PURPOSE: Intimal hyperplasia is a pathologic condition that is commonly observed with the atherosclerotic change of blood vessels; this condition is usually observed after arterial operation and interventions such as... -
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- Phagocytic activity in familial Mediterranean fever
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Keskin G, Inal A, Sengul A, Cindoruk M, Haznedaroglu S, Duranay M, Songur Y
- KMID: 1067108
- Yonsei Med J.
- 2000 Aug;41(4):441-444.
- doi: 10.3349/ymj.2000.41.4.441
Familial Mediterranean fever (FMF) is an autosomal recessive disease. Although the possibility of multiple immunologic mechanisms have been studied, the actual mechanism is still unresolved. Forty-one patients with FMF (24... -
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- Possible roles of LFA-1 and Fc gamma receptors on the functional immaturities of cord blood polymorphonuclear leukocytes
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Kim NA, Choi IH, Shin JS, Park SK, Kim NS, Choi DH, Kim SJ
- KMID: 1729600
- Yonsei Med J.
- 1993 Jun;34(2):126-132.
- doi: 10.3349/ymj.1993.34.2.126
The functional immaturity of PMNs is one of the major causes of overwhelming sepsis in newborns. In this study, we observed functions and surface markers of PMNs to investigate what... -
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- LL-37 inhibits serum amyloid A-induced IL-8 production in human neutrophils
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Lee HY, Kim SD, Shim JW, Lee SY, Yun J, Bae YS
- KMID: 1123806
- Exp Mol Med.
- 2009 May;41(5):325-333.
- doi: 10.3858/emm.2009.41.5.036
Serum amyloid A (SAA) has been regarded as an important mediator of inflammatory responses. The effect of several formyl peptide receptor-like 1 (FPRL1) ligands on the production of IL-8 by... -
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- Intratumoral Administration of Secondary Lymphoid Chemokine and Unmethylated Cytosine-phosphorothioate-guanine Oligodeoxynucleotide Synergistically Inhibits Tumor Growth in Vivo
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Oh SM, Oh K, Lee DS
- KMID: 1785982
- J Korean Med Sci.
- 2011 Oct;26(10):1270-1276.
- doi: 10.3346/jkms.2011.26.10.1270
Secondary lymphoid tissue chemokine (SLC), which is expressed in T cell zones of secondary lymphoid organs, including the spleen and lymph nodes, strongly recruits both T lymphocytes and mature dendritic... -
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- Eosinophil Inflammation of Nasal Polyp Tissue: Relationships with Matrix Metalloproteinases, Tissue Inhibitor of Metalloproteinase-1, and Transforming Growth Factor-beta1
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Park HS, Kim SS, Kim HA, Suh YJ, Lee SK, Nahm DH, Lee YM
- KMID: 1099801
- J Korean Med Sci.
- 2003 Feb;18(1):97-102.
- doi: 10.3346/jkms.2003.18.1.97
Eosinophil and mast cell infiltrations are consistent findings in nasal polyp tissue. Previous studies have shown that matrix metalloproteinases (MMPs) may be involved in eosinophil infiltration in airway mucosa of... -
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