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Clinical trial of chelating agents administration on subelinical lead poisoning workers

Jung KY, Kim WS, Lee HR, Kim DI, Hong YS, Kim JY

  • KMID: 1694524
  • Korean J Occup Environ Med.
  • 1993 Sep;5(2):223-232.
No abstract available.
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Wilson disease

Lee JS

  • KMID: 2168067
  • Hanyang Med Rev.
  • 2005 Aug;25(3):4-11.
Wilson disease is an autosomal recessive disorder caused by a deficient ATP7B activity. Copper is an important mineral in the body involved in mitochondrial respiration, melanin biosynthesis, dopamin metabolism, iron...
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Change of Laboratory Parameters during Treatment of Lead Poisoning

Yoo BK

  • KMID: 2282027
  • Korean J Prev Med.
  • 1978 Oct;11(1):76-82.
In order to study the change of laboratory parameters of lead poisoning, 8 persons who had not been treated previously for lead poisoning (Group 1) and 6 persons who had...
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Economic Evaluation of Iron Chelation Agents: Oral Deferasirox versus Infusional Deferoxamine

Kim JH, Kim YH

BACKGROUND: Patients with transfusional iron overload have relied on treatment with deferoxamine, a standard chelating agent. Deferoxamine is administered by intravenous or subcutaneous infusion over an 8~12 hour period 5~7...
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Management of Poisoning by Chemical Agents

Hong YC

Obtaining a complete and accurate history is one of the most crucial steps in the initial diagnosis and subsequent management of the poisoned patients. This information can then be integrated...
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Development of Macrocyclic Ligands for Stable Radiometal Complexes

Yoo J, Lee J

  • KMID: 2256975
  • Korean J Nucl Med.
  • 2005 Aug;39(4):215-223.
Current interest in the regioselective N-functionalization of tetraazacycloalkanes (cyclen and cyclam) stems mainly from their complexes with radioactive metals for applications in diagnostic (64Cu, 111In, 67Ga) and therapeutic (90Y) medicine,...
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A Comparison Study of Radiostrontium Chelation with Chitin, Chitosan, EDTA and DTPA

Bom HS, Kim YH, Kim JY

  • KMID: 2078716
  • Korean J Nucl Med.
  • 1998 Aug;32(4):391-395.
PURPOSE: Chitin and chitosan are nontoxic natural chelators that chelate radiostrontium effectively. The purpose of this study was to compare radiostrontium chelation of chitin and chitosan with that of well...
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Pregnancy in a woman with Wilson's disease treated with zinc: A case report

Bhattacharyya SK, Saha SP, Samanta J, Roychowdhuri A

Wilson's disease is a rare hereditary disorder of copper metabolism affecting 30 per million populations. Copper get deposited in liver, brain and kidney due to decreased hepato-cellular excretion and leading...
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Guanosine 5′-monophosphate-chelated calcium and iron feed additives maintains egg production and prevents Salmonella Gallinarum in experimentally infected layers

Noh HJ, Kim H, Heo SJ, Cho HH, Koh HB

We evaluated the effects of guanosine 5′-monophosphate (GMP)-chelated calcium and iron (CaFe-GMP) on health and egg quality in layers experimentally infected with Salmonella Gallinarum. In this study, a CaFe-GMP feed...
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Iron chelating agent, deferoxamine, induced apoptosis in Saos-2 osteosarcoma cancer cells

Park EH, Lee HJ, Lee SY, Kim SY, Yi HK, Lee DY, Hwang PH

PURPOSE: Iron is a critical nutritional element that is essential for a variety of important biological processes, including cell growth and differentiation, electron transfer reactions, and oxygen transport, activation, and...
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In Vivo Nuclear Imaging of Apoptosis

Lee TS, Cheon GJ

  • KMID: 2078812
  • Korean J Nucl Med.
  • 2004 Apr;38(2):190-197.
Apoptosis plays a role in the pathophysiology of many kinds of diseases and in the response of treatment. Compared to the necrosis, the apoptosis is a genetically controlled and energy-dependent...
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Comparison of Immune Responses Induced by Deferoxamine and Deferasirox

Jung YS, Bae EY, Chung NG, Cho B, Kim HK, Min CK, Han CW, Kim HS, Jeong DC

BACKGROUND: The iron chelating agents (ICA) have various biological effects besides iron chelation. We investigated the immunomodulatory effects of Deferasirox (DFS) compared to Deferoxamine (DFO). METHODS: Spleen cells (SP) were obtained...
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Progress of Coordination and Utilization of Zirconium-89 for Positron Emission Tomography (PET) Studies

La MT, Tran VH, Kim HK

Radiometals have been commonly used in medical applications, and utilization of such metals continues to be an attractive research area. In particular, a variety of radiometals have been developed and...
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Evaluation of mercury exposure level, clinical diagnosis and treatment for mercury intoxication

Ye BJ, Kim BG, Jeon MJ, Kim SY, Kim HC, Jang TW, Chae HJ, Choi WJ, Ha MN, Hong YS

Mercury occurs in various chemical forms, and it is different to health effects according to chemical forms. In consideration of the point, the evaluation of the mercury exposure to human...
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Analysis of the shelf life of chitosan stored in different types of packaging, using colorimetry and dentin microhardness

Cruz-Filho AMd, Bordin AR, Souza-Flamini LE, Guedes DF, Saquy PC, Silva RG, Pécora JD

OBJECTIVES: Chitosan has been widely investigated and used. However, the literature does not refer to the shelf life of this solution. This study evaluated, through the colorimetric titration technique and...
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Neuroprotective Effects of BAPTA-AM: A Dose-response Study and Estimation of Therapeutic Window

Oh JI, Yoo KH, Park YK, Chung HS, Lee KC, Lee HK

  • KMID: 1955231
  • J Korean Neurosurg Soc.
  • 1997 Mar;26(3):326-334.
In central neurons, an excessive or sustained rise in the concentration of free cytoplasmic Ca2+ ions([Ca2+]i) after hypoxia may promote rapid neurodegeneration both in vitro and in vivo. Treating cells...
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Purification Siderophore from Vibrio mimicus ATCC 33653 and its Effect to Bacterial Pathogenecity

Park SJ, Ju SA, Heo MS, Jung CR, Ju JW

  • KMID: 1543609
  • J Korean Soc Microbiol.
  • 1999 Oct;34(5):461-470.
Growth under conditions of iron-restriction and the production of siderophore was examined in Vibrio mimicus ATCC 33653. This strain grew and multiplied in the presence of the high-affinity iron chelators...
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Radiological Accident and Acute Radiation Syndrome

Roh HK

  • KMID: 2101634
  • J Korean Soc Clin Toxicol.
  • 2011 Dec;9(2):39-48.
In mass casualty situation due to radiological accidents, it is important to start aggressive management with rapid triage decisions. External contamination needs immediate decontamination and internal contamination should be treated...
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Three Cases of Superficial Siderosis

Kim BG, Roh JK, Jeon BS, Han MH

  • KMID: 2342574
  • J Korean Neurol Assoc.
  • 1996 Sep;14(3):848-854.
Superficial siderosis is a rare condition characterized by hemosiderin deposition in leptomeninges, subpial tissue, brainstem, cerebellum, spinal cord, and cranial nerves. Slowly progressive hearing loss and gait ataxia are invariable...
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Advanced Pharmacotherapy Evidenced by Pathogenesis of Autism Spectrum Disorder

Lee YJ, Oh SH, Park C, Hong M, Lee AR, Yoo HJ, Shin CY, Cheon KA, Bahn GH

  • KMID: 2171125
  • Clin Psychopharmacol Neurosci.
  • 2014 Apr;12(1):19-30.
In clinical practice, pharmacological treatment is mostly focused on behavioral symptoms in everyday life. Nevertheless, persistent effort continues to develop medication for causal treatment. Recent changes in diagnostic criteria from...
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