- Altered Levels of Sphingosine and Sphinganine in Psoriatic Epidermis
-
Moon SH, Kim JY, Song EH, Shin MK, Cho YH, Kim NI
- KMID: 2265872
- Ann Dermatol.
- 2013 Aug;25(3):321-326.
- doi: 10.5021/ad.2013.25.3.321
BACKGROUND: Ceramides are the main lipid component of the stratum corneum and are a structurally heterogeneous and complex group of sphingolipids of which sphingoid bases are the basic structural constituents.... -
- CITED
-
- Close
- SHARE
-
- Close
- Cytotoxic Activity and Structure Activity Relationship of Ceramide Analogues in Caki-2 and HL-60 Cells
-
Kim YJ, Kim EA, Sohn UD, Yim CB, Im C
- KMID: 2071718
- Korean J Physiol Pharmacol.
- 2010 Dec;14(6):441-447.
- doi: 10.4196/kjpp.2010.14.6.441
B13, a ceramide analogue, is a ceramidase inhibitor and induces apoptosis to give potent anticancer activity. A series of thiourea B13 analogues was evaluated for their in vitro cytotoxic activities... -
- CITED
-
- Close
- SHARE
-
- Close
- Cytotoxicities and Quantitative Structure Activity Relationships of B13 Sulfonamides in HT-29 and A549 Cells
-
Lee SK, Park SM, Im C
- KMID: 2285430
- Korean J Physiol Pharmacol.
- 2011 Dec;15(6):423-429.
- doi: 10.4196/kjpp.2011.15.6.423
B13 analogues are being considered as therapeutic agents for cancer cells, since B13 is a ceramide analogue and inhibits ceramidase to promote apoptosis in cancer cells. B13 sulfonamides are assumed... -
- CITED
-
- Close
- SHARE
-
- Close
- Dietary effect of red ginseng extracts mixed with torilis fructus and corni fructus on the epidermal levels of ceramides and ceramide related enzyme proteins in uv-induced hairless mice
-
Lee YJ, Oh IG, Cho Y
- KMID: 2268685
- Korean J Nutr.
- 2012 Jun;45(3):211-217.
- doi: 10.4163/kjn.2012.45.3.211
UV-irradiation is a major factor of photo-aged skin, by which pigmentation, wrinkles and laxity are increased. In addition, the epidermal barrier is disrupted, ultimately causing dryness in photo-aged skin. As... -
- CITED
-
- Close
- SHARE
-
- Close
- The role of ceramidase in murine ovarian granulosa cell death
-
Kim MR, Lee ST, Chung JE, Jo HH, Hwang SJ, Kwon DJ, Lew YO, Lim YT, Kim JH, Lee JW, Kim JH
- KMID: 2272481
- Korean J Obstet Gynecol.
- 2004 Dec;47(12):2453-2458.
OBJECTIVE: One of the models we study is the ovarian granulosa cell (GC), a somatic cell lineage that is critically important for maintenance of the female germ line and many... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparative effect of dietary borage oil and safflower oil on anti-proliferation and ceramide metabolism in the epidermis of essential fatty acid deficient guinea pigs
-
Lee SR, Cho Y
- KMID: 2209898
- J Nutr Health.
- 2015 Aug;48(4):319-326.
- doi: 10.4163/jnh.2015.48.4.319
PURPOSE: Borage oil (BO) and safflower oil (SO) are efficacious in reversing epidermal hyperproliferation, which is caused by the disruption of epidermal barrier. In this study, we compared the antiproliferative... -
- CITED
-
- Close
- SHARE
-
- Close
- A Study on Altered Expression of Serine Palmitoyltransferase and Ceramidase in Psoriatic Skin Lesion
-
Hong KK, Cho HR, Ju WC, Cho Y, Kim NI
- KMID: 1713294
- J Korean Med Sci.
- 2007 Oct;22(5):862-867.
- doi: 10.3346/jkms.2007.22.5.862
Ceramides are the main lipid component maintaining the lamellae structure of stratum corneum, as well as lipid second messengers for the regulation of cellular proliferation and/or apoptosis. In our previous... -
- CITED
-
- Close
- SHARE
-
- Close
