- Antisense GLUT1 RNA suppresses the transforming phenotypes of NIH 3T3 cells transformed by N-Ras
-
Choi JW, Yoon DJ, Lee HW, Han DP, Ahn YH
- KMID: 699859
- Yonsei Med J.
- 1995 Dec;36(6):480-486.
- doi: 10.3349/ymj.1995.36.6.480
An antisense approach was attempted to investigate the role of antisense GLUT1 RNA in suppressing tumor cell phenotypes using N-ras-transformed NIH 3T3 cells. The established cell line transformed by ras... -
- CITED
-
- Close
- SHARE
-
- Close
- Hsp27 modulation of implant-associated metal ion cytotoxicity of osteoblastic cells
-
Yoon JH, Ha DJ, Rim JS, Kwon JJ, Jang HS, Lee ES, Kim DS
- KMID: 1960530
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2006 Mar;28(2):127-135.
OBJECTIVES: The extent of bone formation that occurs at the interface of metallic implants and bone is determined by the number and activity of osteoblastic cells. Stress proteins may be... -
- CITED
-
- Close
- SHARE
-
- Close
- Interaction between chicken protein tyrosine phosphatase 1 (CPTP1)-like rat protein phosphatase 1 (PTP1) and p60v-src in v-src-transformed Rat-1 fibroblasts
-
Jung EJ, Kim CW
- KMID: 1121102
- Exp Mol Med.
- 2002 Dec;34(6):476-480.
CPTP1 is a nontransmembrane chicken protein tyrosine phosphatase having 92% sequence homology to the corresponding 321 amino acids of human protein tyrosine phosphatase 1B (HPTP1B). Using anti-CPTP1 antibody, we... -
- CITED
-
- Close
- SHARE
-
- Close
- Induction of fibronectin gene expression by inhibitors of protein phosphatase type 2B in normal and transformed fibroblasts
-
Rhew JH, Shin YA, Lee BH, Park RW, Kim IS
- KMID: 1029934
- Exp Mol Med.
- 1999 Jun;31(2):71-75.
Two intracellular signal pathways mediated by cAMP and protein kinase C (PKC) were involved in the regulation of FN gene expression (Lee et al., Exp. Mol. Med. 30: 240, 1998). In this... -
- CITED
-
- Close
- SHARE
-
- Close
- Cellular characteristics of primary and immortal canine embryonic fibroblast cells
-
You S, Moon JH, Kim TK, Kim SC, Kim JW, Yoon DH, Kwak S, Hong KC, Choi YJ, Kim H
- KMID: 1094076
- Exp Mol Med.
- 2004 Aug;36(4):325-335.
Using normal canine embryonic fibroblasts (CaEF) that were shown to be senescent at passages 7th-9th, we established two spontaneously immortalized CaEF cell lines (designated CGFR-Ca-1 and -2) from normal senescent... -
- CITED
-
- Close
- SHARE
-
- Close
- Phospholipase D activity is elevated in hepatitis C virus core protein-transformed NIH3T3 mouse fibroblast cells
-
Kim J, Choi BH, Jang KL, Min DS
- KMID: 1123766
- Exp Mol Med.
- 2004 Oct;36(5):454-460.
Hepatitis C Virus (HCV) is associated with a severe liver disease and increased frequency in the development of hepatocellular carcinoma. Overexpression of HCV core protein is known to transform fibroblast... -
- CITED
-
- Close
- SHARE
-
- Close
- The role of Rho GTPases in the regulation of the rearrangement of actin cytoskeleton and cell movement
-
Begum R, Nur-E-Kamal MSA, Zaman MA
- KMID: 1094080
- Exp Mol Med.
- 2004 Aug;36(4):358-366.
The rearrangement of the actin cytoskeleton has been shown to play a critical role in the development of transformation and malignant phenotype of cancer cells. Rho family GTPases regulate the... -
- CITED
-
- Close
- SHARE
-
- Close
- Identification of potential lung cancer biomarkers using an in vitro carcinogenesis model
-
Kim JE, Koo KH, Kim YH, Sohn J, Park YG
- KMID: 1072951
- Exp Mol Med.
- 2008 Dec;40(6):709-720.
- doi: 10.3858/emm.2008.40.6.709
Lung cancer is one of the deadliest and commonly diagnosed neoplasms. Early diagnosis of this disease is critical for improving clinical outcome and prognosis. Because the early stages of lung... -
- CITED
-
- Close
- SHARE
-
- Close
- Characterization of Immortalized Human Corneal Endothelial Cell Line using HPV 16 E6/E7 on Lyophilized Human Amniotic Membrane
-
Kim HJ, Ryu YH, Ahn JI, Park JK, Kim JC
- KMID: 1099072
- Korean J Ophthalmol.
- 2006 Mar;20(1):47-54.
- doi: 10.3341/kjo.2006.20.1.47
PURPOSE: To establish the immortalized human corneal endothelial cell line (IHCEn) by transducing human papilloma virus (HPV) 16 E6/E7 oncogenes, and to identify their characteristics when cultivated on a... -
- CITED
-
- Close
- SHARE
-
- Close
- Evidence for V(H) Gene Replacement in Human Fetal B Cells
-
Lee JS, Cho YJ, Lipsky PE
- KMID: 1571486
- Immune Netw.
- 2002 Jun;2(2):79-85.
- doi: 10.4110/in.2002.2.2.79
BACKGROUND: In contrast to evidences of Ig H chain receptor editing in transformed cell lines and transgenic mouse models, there has been no direct evidence that this phenomenon occurs in... -
- CITED
-
- Close
- SHARE
-
- Close
- Immunohistochemical Study for p53 and hsc70 in Transitional Cell Carcinoma of the Urinary Bladder: Correlation with Histologic Grade, Clinical Stage and DNA Ploidy Pattern
-
Cho H, Cho SJ, Kim HK, Chae YS
- KMID: 2141066
- Korean J Pathol.
- 1995 Dec;29(6):766-775.
Transitional cell carcinoma of the urinary bladder is the most common cancer of the genitourinary tract in Korea and its prognosis is determined by the histologic grade and clinical stage... -
- CITED
-
- Close
- SHARE
-
- Close
- Dedifferentiation of conditionally immortalized hepatocytes with long-term in vitro passage
-
Kim BH, Sung SR, Choi EH, Kim YI, Kim KJ, Dong SH, Kim HJ, Chang YW, Lee JI, Chang R
- KMID: 927131
- Exp Mol Med.
- 2000 Mar;32(1):29-37.
The rat hepatocytes were immortalized using a temperature-sensitive mutant of SV40 large T antigen (tsT) to develop as a possible substitute for primary hepatocytes. Four rat hepatocyte lines that have... -
- CITED
-
- Close
- SHARE
-
- Close
- Suppression of Aurora-A oncogenic potential by c-Myc downregulation
-
Yang S, He S, Zhou X, Liu M, Zhu H, Wang Y, Zhang W, Yan S, Quan L, Bai J, Xu N
- KMID: 994399
- Exp Mol Med.
- 2010 Nov;42(11):759-767.
- doi: 10.3858/emm.2010.42.11.077
The abnormality of serine/threonine kinase Aurora-A is seen in many types of cancers. Although in physiological context it has been shown to play a vital role in cellular mitosis, how... -
- CITED
-
- Close
- SHARE
-
- Close
- Imaging of Viral Thymidine Kinase Gene Expression by Replicating Oncolytic Adenovirus and Prediction of Therapeutic Efficacy
-
Kim EJ, Yoo JY, Choi YH, Ahn KJ, Lee JD, Yun CO, Yun M
- KMID: 2158200
- Yonsei Med J.
- 2008 Oct;49(5):811-818.
- doi: 10.3349/ymj.2008.49.5.811
PURPOSE: We have used a genetically attenuated adenoviral vector which expresses HSVtk to assess the possible additive role of suicidal gene therapy for enhanced oncolytic effect of the virus. Expression... -
- CITED
-
- Close
- SHARE
-
- Close
- Human telomerase catalytic subunit (hTERT) suppresses p53-mediated anti-apoptotic response via induction of basic fibroblast growth factor
-
Jin X, Beck S, Sohn YW, Kim JK, Kim SH, Yin J, Pian X, Kim SC, Choi YJ, Kim H
- KMID: 1104384
- Exp Mol Med.
- 2010 Aug;42(8):574-582.
- doi: 10.3858/emm.2010.42.8.058
Although human telomerase catalytic subunit (TERT) has several cellular functions including telomere homeostasis, genomic stability, cell proliferation, and tumorigenesis, the molecular mechanism underlying anti-apoptosis regulated by TERT remains to be... -
- CITED
-
- Close
- SHARE
-
- Close
- A study of the viral etiology of histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto disease)
-
Huh J, Chi HS, Kim SS, Gong G
- KMID: 1107222
- J Korean Med Sci.
- 1998 Feb;13(1):27-30.
- doi: 10.3346/jkms.1998.13.1.27
Histiocytic necrotizing lymphadenitis (HNL) or Kikuchi's disease is a distinctive, self-limited disorder characterized by necrotizing cervical lymphadenopathy in young individuals. HNL is more prevalent among Asians and is a relatively... -
- CITED
-
- Close
- SHARE
-
- Close
- Mechanism of Humoral and Cellular Immune Modulation Provided by Porcine Sertoli Cells
-
Lee HM, Oh BC, Lim DP, Lee DS, Lim HG, Park CS, Lee JR
- KMID: 1786893
- J Korean Med Sci.
- 2008 Jun;23(3):514-520.
- doi: 10.3346/jkms.2008.23.3.514
The understanding of main mechanisms that determine the ability of immune privilege related to Sertoli cells (SCs) will provide clues for promoting a local tolerogenic environment. In this study, we... -
- CITED
-
- Close
- SHARE
-
- Close
