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Role of neuron and non-neuronal cell communication in persistent orofacial pain

Iwata K, Shinoda M

It is well known that trigeminal nerve injury causes hyperexcitability in trigeminal ganglion neurons, which become sensitized. Long after trigeminal nerve damage, trigeminal spinal subnucleus caudalis and upper cervical spinal...
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Extracellular Toxicity of Motor Neuronal Cells Expressing Mutant Cu/Zn Superoxide Dismutase in Familial ALS Cell Line Model

Choi WJ, Kim HJ, Chun JU, Park KS, Kim SH, Kim MH, Lee KW

  • KMID: 2186009
  • J Korean Neurol Assoc.
  • 2001 Nov;19(6):629-632.
BACKGROUND: The objective of this study is to identify the extracellular toxicity of motor neuronal cells expressing mutant copper-zinc superoxide dismutase in the model of familial amyotrophic lateral sclerosis (FALS),...
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Stimulation of Chondrogenic Differentiation of Mesenchymal Stem Cells

Yu DA, Han J, Kim BS

  • KMID: 1426153
  • Int J Stem Cells.
  • 2012 May;5(1):16-22.
The methods for cartilage repair have been studied so far, yet many of them seem to have limitations due to the low regenerative capacity of articular cartilage. Mesenchymal stem cell...
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Adhesion of CD40-stimulated Germinal Center B Cells to HK Cells Employs the CD11a/CD18-CD54 Interactions

Lee J, Choe J

BACKGROUND: The molecular basis of follicular dendritic cells (FDC)-germinal center (GC) B cell interaction is largely unknown, although this cellular interaction is thought to be important for the whole process...
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Interaction of Mesenchymal Stem Cells and Osteoblasts for in vitro Osteogenesis

Kim H, Lee JH, Suh H

It has recently been reported that bone marrow-derived mesenchymal stem cells (MSCs), which are systemically administrated to different species, undergo site-specific differentiation. This suggests that the tissue specific cells may...
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CD137-CD137 Ligand Interactions in Inflammation

Kwon B

The main stream of CD137 studies has been directed to the function of CD137 in CD8+ T-cell immunity, including its anti-tumor activity, and paradoxically the immunosuppressive activity of CD137, which...
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Distinctive Pattern of Gene Expression in Intestinal and Diffuse Gastric Cancer on cDNA Microarray

Oh CA, An SI, Cho YU, Lee KY, Kim SJ, Hur YS, Choi SK, Hong KC, Shin SH, Kim KR, Woo ZH, Lee SJ

  • KMID: 2210131
  • J Korean Surg Soc.
  • 2005 Apr;68(4):277-287.
Molecular investigations have provided evidence of the involvement of multiple genetic alterations in gastric carcinogenesis. Regarding the clinical, epidemiological and genetic aspects, well and poorly differentiated gastric adenocarcinoma exhibit some...
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The Roles of Intercellular Adhesion Molecule I in T Cell Adhesion Tosynovial Cell in Patients with Rheumatoid Arthritis

Jun JB, Kim DY, Kim TH, Kim SY, Kim PN, Jung SS, Lee IH, Bae SC, Yoo DH, Kim SK, Kim SY

  • KMID: 2202566
  • J Korean Rheum Assoc.
  • 1995 Jul;2(2):119-125.
OBJECTIVE: It has previously been shown that cellular interaction between infiltrating mononuclear cells and synoviocyte are important in the initiation and perpetuation of autoimmune processes in the synovial tissue of...
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Ezrin is an Essential Marker for Metastasis of Gynecologic Cancer

Choi SD

  • KMID: 2365471
  • J Korean Soc Menopause.
  • 2012 Aug;18(2):81-93.
Ezrin, a membrane cytoskeleton linking protein, is a member of ezrin/radixin/moesin (ERM) that regulates cell shape, motility and cell to cell interaction via linking the contractile elements of the cell...
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Generation and Characterization of 1H8 monoclonal antibody against human bone marrow stromal cells

Kang HS, Choi IP

BACKGROUND: Bone marrow stromal cells (BMSCs) express many cell surface molecules, which regulate the proliferation and differentiation of immune cells within the bone marrow. METHODS: To identify cell surface molecules, which...
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Effect of VCAM-1 expression in human endothelial cells by proinflammatory cytokines

Chang YH, Park SK, Moon HB, Lee JD, Kim SW, Hwang OY, Hong HN, Cho YJ

  • KMID: 1907977
  • J Asthma Allergy Clin Immunol.
  • 1999 Apr;19(2):163-172.
BACKGROUND: The expression of adhesion molecules contribute to development of systemic diseases. Vascular cell adhesion molecule-l(VCAM-1) is an endothelial cell membrane glycoprotein that has been implicated in leukocyte/endothelial cell interactions...
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3C8, a new monoclonal antibody directed against a follicular dendritic cell line, HK

Lee IY, Lee JH, Park WS, Nam EC, Shin YO, Choe JS

BACKGROUND: Follicular dendritic cells (FDCs) play key roles during T cell-dependent humoral immune responses by allowing antigen-specific B cells to survive, proliferate, and differentiate within the FDC networks of secondary...
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CD30-Mediated Regulation of Cell Adhesion Molecule Expression on Murine T Cells

Nam SY

BACKGROUND: CD30 is a member of TNF receptor family and expressed on lymphocytes and other hematopoietic cells following activation as well as Hodgkin and Reed- Sternberg cells in Hodgkin's lymphoma....
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Migration of Emperipoletic Erythroblasts Within Kupffer Cells in Human Hepatic Hemopoiesis: Electron Microscopic Study

Lee WB, Yoo DH, Chae HS, Bach JH, Kim SS, Kim KY

  • KMID: 1559109
  • Korean J Anat.
  • 2001 Jun;34(3):231-244.
The presence of erythroblasts within Kupffer cell was studied for transmission electron microscopically with 5 human fetal livers from 11 to 23 weeks of gestation during the high activity of...
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Cell to Cell Interaction Can Activate Membrane-bound APRIL Which Are Expressed on Inflammatory Macrophages

Lee SM, Kim WJ, Suk K, Lee WH

BACKGROUND: APRIL, originally known as a cytokine involved in B cell survival, is now known to regulate the inflammatory activation of macrophages. Although the signal initiated from APRIL has been...
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Gap junction blockage promotes cadmium-induced apoptosis in BRL 3A derived from Buffalo rat liver cells

Hu D, Zou H, Han T, Xie J, Dai N, Zhuo L, Gu J, Bian J, Yuan Y, Liu X, Liu Z

Gap junctions mediate direct communication between cells; however, toxicological cascade triggered by nonessential metals can abrogate cellular signaling mediated by gap junctions. Although cadmium (Cd) is known to induce apoptosis...
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Transforming Growth Factor-beta is a Possible Paracrine Mediator in the Human Endometrial Decidualization

Park DW, Choi DS, Kim MR, Hwang KJ, Jo MY, Ahn SH, Min CK, Ryu HS

  • KMID: 2235702
  • Korean J Fertil Steril.
  • 2003 Mar;30(1):65-75.
OBJECTIVES: To investigate the role of TGF (Transforming growth factor-beta) involved in the paracrinic communication during decidualization between UEC (uterine epithelial cells) and USC (uterine stromal cells), we have employed...
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Expression of Cytokines in Coculture Model with Epithelial Cells and Fibroblasts of Nasal Polyp

Kim SW, Cho JS, Park JK, Lee KH, Cha CI

  • KMID: 1977236
  • Korean J Otolaryngol-Head Neck Surg.
  • 2007 Feb;50(2):134-138.
BACKGROUND AND OBJECTIVES: Nasal polyposis is a chronic inflammatory disease characterized histologically by edematous fluid with sparse fibrous cells, few mucous glands and proliferation of stromal and epithelial cells. There...
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Acebutolol, a Cardioselective Beta Blocker, Promotes Glucose Uptake in Diabetic Model Cells by Inhibiting JNK-JIP1 Interaction

Li Y, Jung NY, Yoo JC, Kim Y, Yi GS

The phosphorylation of JNK is known to induce insulin resistance in insulin target tissues. The inhibition of JNK-JIP1 interaction, which interferes JNK phosphorylation, becomes a potential target for drug development...
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The Role of Activated Hepatic Stellate Cells in Liver Fibrosis, Portal Hypertension and Cancer Angiogenesis

Lee JS, Kim JH

Although hepatic stellate cells, which are liver specific pericytes, have been recognized within the vasculature of the sinusoid for more than one hundred years, the biology and function of these...
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