- Caveolin-1 is involved in high glucose accelerated human glomerular mesangial cell senescence
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Feng X, Gao W, Li Y
- KMID: 2411491
- Korean J Intern Med.
- 2017 Sep;32(5):883-889.
- doi: 10.3904/kjim.2015.254
BACKGROUND/AIMS:: We demonstrated the role of caveolin-1 involved in high glucose (HG)-induced glomerular mesangial cells (GMCs) senescence. METHODS:: HG was used to stimulate GMCs. The telomere lengths were analyzed by Southern... -
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- The Loss of Expression of Caveolin-1 in Gastrointestinal Stromal Tumors
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Kim EJ, Sohn JH, Kim MK, Chae SW, Lee HS, Cho EY, Kim WH
- KMID: 1598237
- Korean J Pathol.
- 2005 Oct;39(5):338-344.
BACKGROUND: The down-regulation of caveolin-1, a putative tumor suppressor gene, has been demonstrated in several types of sarcomas. However, it's not known whether or not the gastrointestinal stromal tumors (GISTs)... -
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- Caveolin-1 and Ki-67 Expression as Prognostic Factors in Clear Cell Carcinoma of the Kidney
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Kim BH, Kim CI, Park CH
- KMID: 2312010
- Korean J Urol.
- 2008 Feb;49(2):99-106.
PURPOSE: Caveolin-1 is proposed to represent a novel tumor suppressor protein and expression of recombinant caveolin-1 is sufficient to restrict the growth potential of transformed cells isolated from primary tumors... -
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- Increased phosphorylation of caveolin-1 in the spinal cord of irradiated rats
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Kim H, Moon C, Kim J, Ahn M, Hyun JW, Park JW, Kim SH, Kim S, Shin T
- KMID: 1106210
- J Vet Sci.
- 2007 Dec;8(4):323-327.
- doi: 10.4142/jvs.2007.8.4.323
Phosphorylation of caveolin-1 occurs during cell activation by various stimuli. In this study, the involvement of caveolin-1 in an irradiation injured spinal cord was examined by analyzing the phosphorylation of... -
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- Diagnostic Utility of Caveolin-1 and MOC-31 in Distinguishing Chromophobe Renal Cell Carcinoma from Renal Oncocytoma
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Lee HW, Lee EH, Lee CH, Chang HK, Rha SH
- KMID: 2315631
- Korean J Urol.
- 2011 Feb;52(2):96-103.
PURPOSE: Renal tumors consist of heterogeneous groups that frequently show complex and overlapping morphology, thus making it difficult to make a correct diagnosis. One of the most problematic differential diagnoses... -
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- Expression of Caveolin-1 in Rat Urinary Bladder with Cyclophosphamide-Induced Cystitis
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Kim SO, Song SH, Lee SC, Cho KA, Yu HS, Hwang IS, Hwang EC, Kwon D
- KMID: 2173021
- Int Neurourol J.
- 2012 Dec;16(4):169-174.
PURPOSE: The purposes of this study were to investigate the effect of cyclophosphamide (CYP)-induced inflammatory cystitis on caveolin 1 in rat urinary bladder and to determine the role of these... -
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- Dietary nobiletin suppresses TGF-β1-Src-caveolin-1 dependent signaling involved with high glucose-induced renal mesangial matrix accumulation
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Kim DY, Kang YH, Kang MK
- KMID: 2471118
- J Nutr Health.
- 2020 Feb;53(1):1-12.
- doi: 10.4163/jnh.2020.53.1.1
PURPOSE: Diabetic nephropathy is one of the most important diabetic complications prompted by chronic hyperglycemia, characterized by glomerulosclerosis, tubular fibrosis, and it eventually causes kidney failure. Nobiletin is a polymethoxyflavone... -
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- Effects of Estrogens on the Expression of Caveolin-1 in the Urinary Bladders of Female Rats
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Kim SO, Song SH, Lee SC, Cho KA, Kim HS, Hwang IS, Hwang EC, Oh KJ, Kwon D
- KMID: 2232786
- Int Neurourol J.
- 2011 Mar;15(1):13-18.
PURPOSE: The purposes of this study were to investigate the effect of hormonal alterations on the expression of caveolin-1 in the urinary bladders of ovariectomized rats and to determine the... -
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- Expression of Caveolin in Hepatocellular Carcinoma: Association with Unpaired Artery Formation and Radiologic Findings
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Choi HN, Kim KR, Park HS, Jang KY, Kang MJ, Lee DG, Kim YK, Cho BH, Cha EJ, Moon WS
- KMID: 760741
- Korean J Hepatol.
- 2007 Sep;13(3):396-408.
- doi: 10.3350/kjhep.2007.13.3.396
BACKGROUND/AIMS: Hepatocellular carcinoma (HCC) is becoming one of the common malignant tumors worldwide, and it is characterized by its high vascularity. Caveolin is the major structural protein in caveolae,... -
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- Caveolin-1 upregulation in senescent neurons alters amyloid precursor protein processing
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Kang MJ, Chung YH, Hwang CI, Murata M, Fujimoto T, Mook-Jung , Cha CI, Park WY
- KMID: 1111405
- Exp Mol Med.
- 2006 Apr;38(2):126-133.
Lipid rafts provide a platform for regulating cellular functions and participate in the pathogenesis of several diseases. However, the role of caveolin-1 in this process has not been elucidated definitely... -
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- Caveolin-1 is involved in reactive oxygen species-induced SHP-2 activation in astrocytes
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Yun JH, Park SJ, Jo A, Kang JL, Jou I, Park JS, Choi YH
- KMID: 1058703
- Exp Mol Med.
- 2011 Dec;43(12):660-668.
- doi: 10.3858/emm.2011.43.12.075
Recent evidence supports a neuroprotective role of Src homology 2-containing protein tyrosine phosphatase 2 (SHP-2) against ischemic brain injury. However, the molecular mechanisms of SHP-2 activation and those governing how... -
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- Effect of Oxidized LDL on the Amount of Insulin Receptor and Gi-proteins in the Caveolae of Bovine Aortic Endothelial Cells (BAEC)
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Jeon SY, Son HS, Lee JM, Moon SD, Yoon KH, Cha BY, Lee KW, Son HY, Kang SK
- KMID: 2010071
- J Korean Diabetes Assoc.
- 2001 Feb;25(1):71-82.
BACKGROUND AND AIMS: Oxidized LDL (ox-LDL) may induce endothelial cell dysfunction and suggested to have an association with atherosclerosis or insulin resistance. Several studies have shown that ox-LDL inhibits signaling... -
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- Exercise type and muscle fiber specific induction of caveolin-1 expression for insulin sensitivity of skeletal muscle
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Oh YS, Kim HJ, Ryu SJ, Cho KA, Park YS, Park H, Kim M, Kim CK, Park SC
- KMID: 1047091
- Exp Mol Med.
- 2007 Jun;39(3):395-401.
It is well known that exercise can have beneficial effects on insulin resistance by activation of glucose transporter. Following up our previous report that caveolin-1 plays an important role in... -
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- Overexpression of Aquaporin-1 and Caveolin-1 in the Rat Urinary Bladder Urothelium Following Bladder Outlet Obstruction
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Kim SO, Song SH, Park K, Kwon D
- KMID: 2233005
- Int Neurourol J.
- 2013 Dec;17(4):174-179.
PURPOSE: This study was designed to investigate the effect of detrusor overactivity induced by partial bladder outlet obstruction (BOO) on the expression of aquaporin 1 (AQP1) and caveolin 1 (CAV1)... -
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- Aldosterone Rapidly Enhances Levels of the Striatin and Caveolin-1 Proteins in Rat Kidney: The Role of the Mineralocorticoid Receptor
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Inthachart K, Manotham K, Eiam-Ong S, Eiam-Ong S
- KMID: 2458632
- Endocrinol Metab.
- 2019 Sep;34(3):291-301.
- doi: 10.3803/EnM.2019.34.3.291
BACKGROUND: Striatin and caveolin-1 (cav-1) are scaffolding/regulating proteins that are associated with salt-sensitive high blood pressure and promote renal sodium and water reabsorption, respectively. The mineralocorticoid receptor (MR) interacts with... -
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- HMG-CoA Reductase Inhibitor Improves Endothelial Dysfunction in Spontaneous Hypertensive Rats Via Down-regulation of Caveolin-1 and Activation of Endothelial Nitric Oxide Synthase
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Suh JW, Choi DJ, Chang HJ, Cho YS, Youn TJ, Chae IH, Kim KI, Kim CH, Kim HS, Oh BH, Park YB
- KMID: 1713826
- J Korean Med Sci.
- 2010 Jan;25(1):16-23.
- doi: 10.3346/jkms.2010.25.1.16
Hypertension is associated with endothelial dysfunction and increased cardiovascular risk. Caveolin-1 regulates nitric oxide (NO) signaling by modulating endothelial nitric oxide synthase (eNOS). The purpose of this study was to... -
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- Interleukin-1beta Decreases Caveolin-1 Expression in Human Nasal Epithelium
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Kim M, Kim BM, Choi YS, Han GS, Yoon SY, Park CS, Shin MK, Jang TY
- KMID: 2276827
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2008 Jan;51(1):46-50.
BACKGROUND AND OBJECTIVES: Caveolin-1 (Cav-1) is the structural protein that is necessary for the formation of caveolae membrane domains. It is known as an inhibitor of various signaling pathways and... -
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- Ubiquitin C-terminal Hydrolase L1 Regulates Lipid Raft-dependent Endocytosis
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Kang SJ, Kim JS, Park SM
- KMID: 2424732
- Exp Neurobiol.
- 2018 Oct;27(5):377-386.
- doi: 10.5607/en.2018.27.5.377
Ubiquitin C-terminal hydrolase L1 (UCH-L1) is a deubiquitinating enzyme that is highly expressed in neurons, and gathering evidence indicates that UCH-L1 may play pathogenic roles in many neurodegenerative disorders such... -
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- The Effects of N-acetylcystein and Epigallocatechin-3-Gallate in Ischemia-Reperfusion Injury of Rat Lungs
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Haam S, Lee JG, Lee S, Paik HC, Lim BJ
- KMID: 2202585
- J Korean Soc Transplant.
- 2015 Sep;29(3):130-138.
- doi: 10.4285/jkstn.2015.29.3.130
BACKGROUND: Ischemia-reperfusion injury (IRI) is a major cause of early graft dysfunction after lung transplantation. The aim of this study was to assess the effects of N-acetylcystein (NAC) and epigallocatechin-3-gallate... -
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- Comparative Study of Metaplastic Breast Carcinoma and Triple-Negative Breast Carcinoma Using Histologic and Immunohistochemical Analyses
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Kim JY, Kim T, Cho EY
- KMID: 2277537
- Korean J Pathol.
- 2010 Dec;44(6):605-612.
BACKGROUND: Metaplastic carcinoma of the breast is a rare subtype of breast cancer, which is characterized by estrogen receptor/progesterone receptor and HER2 negativity. METHODS: Tissue specimens from 60 metaplastic breast cancer... -
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