- Trichostatin A induces apoptosis in lung cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway
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Kim HR, Kim EJ, Yang SH, Jeong ET, Park C, Lee JH, Youn MJ, So HS, Park R
- KMID: 1115939
- Exp Mol Med.
- 2006 Dec;38(6):616-624.
Trichostatin A (TSA), originally developed as an antifungal agent, is one of potent histone deacetylase (HDAC) inhibitors, which are known to cause growth arrest and apoptosis induction of transformed cells,... -
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- The Synergistic Apoptotic Interaction of Indole-3-Carbinol and Genistein with TRAIL on Endometrial Cancer Cells
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Parajuli B, Shin SJ, Kwon SH, Cha SD, Lee HG, Bae I, Cho CH
- KMID: 1786959
- J Korean Med Sci.
- 2013 Apr;28(4):527-533.
- doi: 10.3346/jkms.2013.28.4.527
Induction of apoptosis in target cells is a key mechanism by which chemotherapy promotes cell killing. The purpose of this study was to determine whether Indole-3-Carbinol (I3C) and Genistein in... -
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- alpha-Tocopheryl succinate potentiates the paclitaxel-induced apoptosis through enforced caspase 8 activation in human H460 lung cancer cells
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Lim SJ, Choi MK, Kim MJ, Kim JK
- KMID: 1009395
- Exp Mol Med.
- 2009 Oct;41(10):737-745.
- doi: 10.3858/emm.2009.41.10.080
Paclitaxel is one of the chemotheraputic drugs widely used for the treatment of nonsmall cell lung cancer (NSCLC) patients. Here, we tested the ability of alpha-tocopheryl succinate (TOS), another promising... -
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- Bucillamine prevents cisplatin-induced ototoxicity through induction of glutathione and antioxidant genes
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Kim SJ, Hur JH, Park C, Kim HJ, Oh GS, Lee JN, Yoo SJ, Choe SK, So HS, Lim DJ, Moon SK, Park R
- KMID: 2155407
- Exp Mol Med.
- 2015 Feb;47(2):e142.
- doi: 10.1038/emm.2014.112
Bucillamine is used for the treatment of rheumatoid arthritis. This study investigated the protective effects of bucillamine against cisplatin-induced damage in auditory cells, the organ of Corti from postnatal rats... -
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- Growth Inhibition of Hepatocellular Carcinoma Huh7 Cells by Lactobacillus casei Extract
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Han DJ, Kim JB, Park SY, Yang MG, Kim H
- KMID: 1793166
- Yonsei Med J.
- 2013 Sep;54(5):1186-1193.
- doi: 10.3349/ymj.2013.54.5.1186
PURPOSE: Lactobacillus casei (L. casei) is known to exert anti-proliferation effects on many types of cancer cells. However, the effect of L. casei on liver cancer has not been reported.... -
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- Kurarinone promotes TRAIL-induced apoptosis by inhibiting NF-kappaB-dependent cFLIP expression in HeLa cells
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Seo OW, Kim JH, Lee KS, Lee KS, Kim JH, Won MH, Ha KS, Kwon YG, Kim YM
- KMID: 1401757
- Exp Mol Med.
- 2012 Nov;44(11):653-664.
This study was designed to investigate the effects of the prenylated flavonoid kurarinone on TNF-related apoptosis inducing ligand (TRAIL)-induced apoptosis and its underlying mechanism. A low dose of kurarinone had... -
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