- Effects of Magnesium sulfate on the expression of caspase-3 and caspase-9 of cytotrophoblasts under hypoxic condition
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Lee GS, Kim SJ, Hur M, Park SH, Lee HJ, Lee WS, Shin JC
- KMID: 2076856
- Korean J Obstet Gynecol.
- 2003 Mar;46(3):647-650.
OBJECTIVE: To determine the effect of magnesium sulfate (MgSO4) on the expression of caspase-3 and caspase-9 of cytotrophoblasts in vitro under normal and hypoxic condition as assessed immunoblot analyses. METHODS: Normal... -
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- A Study of Apoptosis in Pemphigus Vulgaris
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Roh BH, Whang KU, Cho MK, Park YL, Lee JS, Lee CW
- KMID: 2087378
- Korean J Dermatol.
- 2007 Jul;45(7):650-658.
BACKGROUND: Pemphigus vulgaris is an autoimmune bullous dermatoses of skin and mucosa characterized by loss of adhesion between keratinocytes, a process known as acantholysis. Apoptosis, programmed cell death, may participate... -
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- Caspase 3 and Ki-67 Immunoreactivity and Its Correlation with Frequency of Apoptosis in Gastric Adenomas and Carcinomas
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Sohn JH, Chae SW, Choi KC, Shin HS
- KMID: 1725815
- Korean J Pathol.
- 2001 Aug;35(4):286-290.
BACKGROUND: Apoptosis, also known as programmed cell death, is under genetic control and is mediated by apoptosis-specific genes, certain oncogenes and tumor suppressor genes. Caspase 3, a group of cystein... -
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- Effect of Hypoxia on the Signal Transduction of Apoptosis in Osteoblasts
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Park YJ, Oh ST, Kang KH, Kim SC
- KMID: 1976475
- Korean J Orthod.
- 2003 Dec;33(6):453-463.
Mammalian cell is critically dependent on a continuous supply of oxygen. Even brief periods of oxygen deprivation can result in profound cellular damage. The aim of this study was to... -
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- Analysis of expression of survivin, caspase 3, and p53 protein in cervical neoplasia comparing with Ki-67 index
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Cha JY, Cho TI, Park TY, So JS, Choi SK, Park ES
- KMID: 1979498
- Korean J Gynecol Oncol.
- 2008 Mar;19(1):17-25.
- doi: 10.3802/kjgo.2008.19.1.17
OBJECTIVE: The aim of this study was to determine the role of survivin, caspase 3, p53 and Ki-67 expression in the carcinogenesis of cervical carcinoma and aggressiveness of cervical intraepithelial... -
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- Requirement of ERK Activation in Hypoxia Induced Caspase Activation and Apoptosis of Cultured Tubular Cells
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Ko GJ, Lee JW, Choi HM, Hyun YY, Ko YS, Jo SK, Cho WY, Kim HK
- KMID: 2254155
- Korean J Nephrol.
- 2006 Mar;25(2):185-194.
BACKGOUND: Renal tubular epithelial cells are primary target for hypoxic injury. Hypoxia induced tubular cell apoptosis has been reported previously and thought to be important mechanism of renal dysfunction in... -
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- The Expression of Bcl-2, Bax, Cytochrome C and Caspase-3 in Camptothecin-Induced Apoptosis of Mouse 3T3 Fibroblasts
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Ahn YJ, Lee MS, Kang G
- KMID: 2073723
- Korean J Pathol.
- 2002 Apr;36(2):71-76.
BACKGROUND: Camptothecin (CPT), which has been used for cancer treatment and apoptosis as an inhibitor of DNA topoisomerase I. We investigated the possibility that camptothecin induces anti-appoptotic bcl-2 and pro-apoptotic... -
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- Expression of telomerase RNA and caspase-3 in cervical intraepithelial lesions and invasive carcinoma
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Kim YO, Lee CJ
- KMID: 2244564
- Korean J Gynecol Oncol.
- 2007 Jun;18(2):131-138.
OBJECTIVE: Telomerase is an RNA-dependent DNA polymerase that synthesizes TTAGGG telomeric DNA. It has been detected in a variety of human malignancies, suggesting that it's activity may play a role... -
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- Effect of Inonotus Obliques Extracts on Proliferation and Caspase-3 Activity in Human Castro-Intestinal Cancer Cell Lines
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Hwang YJ, Noh GW, Kim SH
- KMID: 2235853
- Korean J Nutr.
- 2003 Jan;36(1):18-23.
We studied the effects of hot water extract of Inonotus obliquos mushroom on the proliferation and apoptosis of the human colon adenocarcinoma, HT-29 and the human stomach adenocarcinoma, SNU-484 cell.... -
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- Effect of radiation dose variation on expression of caspase-3 in rat submandibular glands
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Kwon KJ, Choi YS, Hwang EH, Lee SR, Koh KJ
- KMID: 2270874
- Korean J Oral Maxillofac Radiol.
- 2006 Mar;36(1):7-15.
PURPOSE: To investigate the caspase-3 expression in the acinar and ductal cells of rat submandibular glands after the irradiation of various doses. MATERIALS AND METHODS: The male Sprague-Dawley rats weighing approximately... -
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- Apoptotic Effects of Co-Treatment with a Chios Gum Mastic and Eugenol on G361 Human Melanoma Cells
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Jo JB, Oh SH, Kim IR, Kim GC, Kwak HH, Park BS
- KMID: 2170780
- Int J Oral Biol.
- 2013 Sep;38(3):101-110.
We investigated the synergistic apoptotic effects of co-treatments with Chios gum mastic (CGM) and eugenol on G361 human melanoma cells. An MTT assay was conducted to investigate whether this co-treatment... -
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- Antitumor and Apoptosis Induction Effects of Paeonol on Mice Bearing EMT6 Breast Carcinoma
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Ou Y, Li Q, Wang J, Li K, Zhou S
- KMID: 2170629
- Biomol Ther.
- 2014 Jul;22(4):341-346.
Paeonol is a major phenolic micromolecular component of Moutan cortex Radicis, a traditional Chinese Medicine. It has shown antitumor effects in previous studies; however, the underlying mechanisms remain unknown. This... -
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- Role of p-38 MAP Kinase in apoptosis of hypoxia-induced osteoblasts
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Yoon JH, Jeong AJ, Kang KH, Kim SC
- KMID: 1976489
- Korean J Orthod.
- 2003 Jun;33(3):169-183.
Tooth movement by orthodontic force effects great tissue changes within the periodontium, especially by shifting the blood flow in the pressure side and resulting in a hypoxic state of low... -
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- Effects of Curcumin on Apoptosis in SW480 Human Colon Cancer Cell Line
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Choi OS, Kim WK
- KMID: 2269720
- Korean J Nutr.
- 2004 Jan;37(1):31-37.
Curcumin, a natural compound extracted from rhizomes of Curcuma longa, has been shown to possess potent antiinflammatory and anti-tumor activity. The mechanism by which curcumin initiates apoptosis remains poorly understood.... -
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- The Protective Mechanism of Zinc in Fungal Metabolte Gliotoxin - induced Apoptosis
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Park JS, So HS, Kim MS, Jung BH, Choi IJ, Jin GH, Jin SH, Kim NS, Cho KH, Park R
- KMID: 2099311
- J Korean Soc Microbiol.
- 1999 Dec;34(6):501-512.
Gliotoxin, a fungal metabolite, is one of the epipolythiodioxopiperazine classes and has a variety of effects including imrnunomodulatory and apoptotic agents. This study is designed to evaluate the effect of... -
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- Expression of Survivin in Human Colorectal Cancer Tissues
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Lee RA, Kim KH, Shim KS
- KMID: 2334192
- J Korean Soc Coloproctol.
- 2000 Jun;16(3):131-138.
Survivin, the recently discovered apoptosis inhibitor of inhibitor of apoptosis (IAP) family is located in chromosome 17q25. It is found only in fetal tissue and transformed tissue but is never... -
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- Cell Death Mechanisms in Esophageal Squamous Cell Carcinoma Induced by Vesicular Stomatitis Virus Matrix Protein
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Douzandegan Y, Tahamtan A, Gray Z, Nikoo HR, Tabarraei , Moradi A
- KMID: 2456577
- Osong Public Health Res Perspect.
- 2019 Aug;10(4):246-252.
- doi: 10.24171/j.phrp.2019.10.4.08
OBJECTIVES: Vesicular stomatitis virus (VSV) is under development as an oncolytic virus due to its preferential replication in cancer cells and oncolytic activity, however the viral components responsible have not... -
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- Apoptotic Pathway Induced by Dominant Negative ATM Gene in CT-26 Colon Cancer Cells
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Lee JC, Yi HK, Kim SY, Lee DY, Hwang PH, Park JW
- KMID: 2335743
- J Korean Pediatr Soc.
- 2003 Jul;46(7):679-686.
PURPOSE: Ataxia telangiectasia mutated(ATM) is involved in DNA damage responses at different cell cycle checkpoints, and signalling pathways associated with regulation of apoptosis in response to ionizing radiation(IR). However, the... -
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- Significance of Expression of Cell Cycle Related Proteins and Apoptosis Related Proteins in Follicular Adenoma and Follicular Carcinoma of Thyroid
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Hwang JY, Choi YS, Park SJ
- KMID: 2040598
- J Korean Surg Soc.
- 2009 Jan;76(1):7-14.
- doi: 10.4174/jkss.2009.76.1.7
PURPOSE: To explore the role of cell cycle regulators and apoptosis regulators in carcinogenesis of thyroid, the expression of cell cycle related proteins (cyclin D1, Ki-67) and apoptosis related proteins... -
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- A Study on Apoptotic Signaling Pathway in HL-60 Cells Induced by Radiation
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Kim HJ, Moon SK, Lee JH, Moon SR
- KMID: 2097162
- J Korean Soc Ther Radiol Oncol.
- 2001 Jun;19(2):153-162.
PURPOSE: The mechanical insights of death of cancer cells by ionizing radiation are not yet clearly defined. Recent evidences have demonstrated that radiation therapy may induce cell death via activation... -
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