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NLRP3 Inflammasome and Host Protection against Bacterial Infection

Kim JJ, Jo EK

The inflammasome is a multi-protein complex that induces maturation of inflammatory cytokines interleukin (IL)-1beta and IL-18 through activation of caspase-1. Several nucleotide binding oligomerization domain-like receptor family members, including NLRP3,...
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The adaptor protein LAD/TSAd mediates laminin-dependent T cell migration via association with the 67 kDa laminin binding protein

Park E, Choi Y, Ahn E, Park I, Yun Y

The adaptor protein, LAD/TSAd, plays essential roles in T cell activation. To further understand the functions of this protein, we performed yeast two-hybrid screening using TSAd as bait and identified...
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Folate Receptor Targeted Imaging Using Poly (ethylene glycol)-folate: In Vitro and In Vivo Studies

Kim SL, Jeong HJ, Kim EM, Lee CM, Kwon TH, Sohn MH

The aim of this study was to ascertain the folate receptor (FR) targetability by an in vitro study and to acquire FR-targeted images in vivo models by using synthetic folate...
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Bis induces growth inhibition and differentiation of HL-60 cells via up-regulation of p27

Seo YJ, Jeon MH, Lee JH, Lee YJ, Youn HJ, Ko JH, Lee JH

  • KMID: 1116208
  • Exp Mol Med.
  • 2005 Dec;37(6):624-630.
Bis (Bag-3, CAIR), a Bcl-2-interacting protein, promotes the anti-apoptotic activity of Bcl-2 and increased levels of Bis have been observed in several disease models. The involvement of Bcl-2 and some...
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