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The pathophysiology of ulcerative colitis caused by hydrolyzed carrageenan in the guinea pig

Song IS, Kim NY, Jung HC, Lee HS, Yoon YB, Kim CY, Kim WH

  • KMID: 1698196
  • Korean J Intern Med.
  • 1992 Sep;43(3):307-323.
No abstract available.
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Carrageenan-Induced Hyperalgesia Is Partially Alleviated by Endomorphin-1 Locally Delivered into Inflamed Paws In Rat

Lee SE, Shin HK

  • KMID: 1607523
  • Korean J Physiol Pharmacol.
  • 2003 Dec;7(6):369-373.
This study was performed to test whether endomorphin-1 has analgesic effect, when locally administrated into inflamed peripheral tissue. Carrageenan suspension (0.5%) was injected intraplantarly into the right paw of Sprague-Dawley...
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Effect of Carrageenan-induced Inflammatory Muscle Pain on Gastrocnemius Muscle Tendon in the Rat

Heo H, Lee YS, Lee EM, Lee KC

BACKGROUND: It has been suggested that muscle pain may induce skeletal muscle tendon damage, but the mechanism of this process is not known. The purpose of this study was to...
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Microscopic Findings in a Muscular Pain Induced Murine Model

Ha DH, Cho YW, Choi YS, Lee KC, Lee JH

BACKGROUND: It has been suggested that muscular pain may induce skeletal muscle damage. But the mechanism of such skeletal muscle damage is not known. This study was performed to investigate...
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Expression of the spinal 5-HT7 receptor and p-ERK pathway in the carrageenan inflammatory pain of rats

Cho SY, Ki HG, Kim JM, Oh JM, Yang JH, Kim WM, Lee HG, Yoon MH, Choi JI

BACKGROUND: Although the inhibitory role of the 5-hydroxytrypatmine receptor 7(5-HT7R) on nociceptive processing is generally recognized, an excitatory effect associated with a reduced 5-HT7R expression has also been observed in...
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Oocyst production and immunogenicity of Cryptosporidium baileyi in chickens and mallards

Rhee JK, Jang BG, Park BK

Two-day-old chickens and mallards were orally inoculated with one of 5 doses varying from 2 x 10(2) to 2 x 10(6) of C. baileyi oocysts per individual. Generally, the more...
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Protective Effect of Orally Administrated Dandelion Against Carrageenan-induced Ankle Arthritis in Rats

Sur BJ, Koh YJ, Choi HD, Shim I, Lee H, Hahm DH

Dandelion (DA) possesses the therapeutic ability to eliminate heat and alleviating swelling, choleresis, dieresis, and inflammation. In order to investigate the anti-arthritic effect of DA, several behavioral parameters such as...
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Effects of hyaluronan on carrageenan-induced synovitis in rat TMJ

Lee MJ, Han KJ, Kwon HJ, Jung HS, Cho SW

Nitric oxide is one of many proinflammatory mediators that are involved in temporomandibular joint (TMJ) inflammatory disorder and is synthesized by inducible nitric oxide synthase (iNOS). iNOS is transcriptionally regulated...
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The Distribution of Fibronectin in the Experimental Keratitis of Rabbit

Lee DS, Kim JD

  • KMID: 2336402
  • J Korean Ophthalmol Soc.
  • 1987 Apr;28(2):319-326.
The distribution of fibronection was investigated in the carrageenan-induced keratitis of rabbitis. Keratitis was induced by the injection of carrageenan into corneas of the rabbits, and specimens were taken at...
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Effects of Electroacupuncture with Different Frequencies on the Spinal c-fos and Inotropic Glutamate Receptor Expression in Carrageenan-injected Rat

Lee JH, Choi YH, Choi BT

  • KMID: 1517130
  • Korean J Phys Anthropol.
  • 2004 Mar;17(1):11-18.
We investigated the comparative effects of electroacupuncture (EA) with different frequency on the spinal c-fos and inotropic glutamate receptor expression in carrageenan-injected rats. Bilateral EA stimulation with 2, 15 and...
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Synergistic anti-inflammatory effects of Laminaria japonica fucoidan and Cistanche tubulosa extract

Kyung J, Kim D, Park D, Yang YH, Choi EK, Lee SP, Kim TS, Lee YB, Kim YB

The anti-inflammatory effects of fuciodan and Cistanche tubulosa (CT) extract were investigated in vitro macrophage culture system and in vivo carrageenan-induced air pouch inflammation model. CT extract inhibited nitric oxide...
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Anti-inflammatory effects of Houttuynia cordata supercritical extract in carrageenan-air pouch inflammation model

Kim D, Park D, Kyung J, Yang YH, Choi EK, Lee YB, Kim HK, Hwang BY, Kim YB

Anti-inflammatory effects of Houttuynia cordata supercritical extract (HSE) were investigated in rat carrageenan-air pouch model. Oral administration of HSE (50-200 mg/kg) suppressed carrageenan-induced exudation and albumin leakage, as well as...
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Bee venom stimulation of a lung meridian acupoint reduces inflammation in carrageenan-induced pleurisy: an alternative therapeutic approach for respiratory inflammation

Choi HS, Kang SY, Roh DH, Choi SR, Ryu Y, Lee JH

Respiratory inflammation is a frequent and fatal pathologic state encountered in veterinary medicine. Although diluted bee venom (dBV) has potent anti-inflammatory effects, the clinical use of dBV is limited to...
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Differential expression of spinal γ-aminobutyric acid and opioid receptors modulates the analgesic effects of intrathecal curcumin on postoperative/inflammatory pain in rats

Ju J, Shin JY, Yoon JJ, Yin M, Yoon MH

BACKGROUND: Curcumin is traditionally used as an herbal medicine. We explored the efficacy of intrathecal curcumin in relieving both postoperative and inflammatory pain and elucidated the mechanisms of action of...
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Reduction of Spinal Cyclooxygenase-2 with Transcutaneous Electrical Nerve Stimulation and Cold Therapy in Rats of Carrageenan-induced Inflammatory Muscle Pain

Paek YW, Chae YW, Kim JW

  • KMID: 2092809
  • Korean J Anat.
  • 2003 Oct;36(5):397-403.
The purpose of this study was to investigate the effects of transcutaneous electrical nerve stimulation (TENS) and cold therapy on cyclooxygenase-2 (COX-2) expression in lumbar spinal cord and on secondary...
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The Effect of Arthritic Induction on Skeletal Muscle and Tendons in the Rat

Choi Y, Cho Y

BACKGROUND: The purpose of this study was to investigate the changes in the gastrocnemius muscle and patellar ligament of Sprague-Dawley rat after knee joint arthritis induction. METHODS: Arthritis was induced...
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The anti-inflammatory effect of Indonesian Areca catechu leaf extract in vitro and in vivo

Lee KP, Sudjarwo G, Kim JS, Dirgantara S, Maeng WJ, Hong H

  • KMID: 2313738
  • Nutr Res Pract.
  • 2014 Jun;8(3):267-271.
BACKGROUND/OBJECTIVES: Overproduction of nitric oxide (NO) by the inducible nitric oxide synthase (iNOS) enzyme can cause inflammation. Cyclooxygenase-2 (COX-2) is also involved in the inflammatory response through regulation of nuclear...
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Effects of Intra-articular Injection of Agmatine and Clonidine into the Knee Joint Cavity on the Induction and Maintenance of Arthritic Pain in Rats

Lee MJ, Shim HS, Seol GH, Kim PJ, Han SH, Yee J, Kim C, Lee KC, Kim HY, Min SS

BACKGROUND: Previous studies suggest that systemic administration of agmatine, endogenous ligand for imidazoline receptors has anti-hypernociceptive effects in experimental animal. However the peripheral effects of agmatine on inflammatory pain have...
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Oocyst production and immunogenicity of Cryptosporidium muris (strain MCR) in mice

Rhee JK, Yook SY, Park BK

Three-week-old ICR SPF mice were orally inoculated with one of 5 doses ranging from 2 x 10(2) to 2 x 10(6) oocysts of Cryptosporidium muris (strain MCR) per mouse. Oocyst...
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Effects of NOS Inhibitors on Arthritis and Arthritic Pain in Rats

Min SS

  • KMID: 1512890
  • Korean J Physiol Pharmacol.
  • 2007 Dec;11(6):253-257.
Among the arthritis symptoms, chronic pain is the most serious, and it can profoundly affect the quality of human life. Unfortunately, the mechanism of development in arthritis and arthritic pain...
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