- Clinical Efficacy of Belotecan (CKD-602), Newly Developed Camptothecin Analog, in the 2nd Line Treatment of Relapsed Small Cell Lung Cancer
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Ban HJ, Oh IJ, Kim KS, Ju JY, Kwon YS, Kim YI, Lim SC, Kim YC
- KMID: 2319153
- Tuberc Respir Dis.
- 2009 Feb;66(2):93-97.
No abstract available. -
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- Antitumor Effects of Camptothecin Combined with Conventional Anticancer Drugs on the Cervical and Uterine Squamous Cell Carcinoma Cell Line SiHa
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Ha SW, Kim YJ, Kim W, Lee CS
- KMID: 2071660
- Korean J Physiol Pharmacol.
- 2009 Apr;13(2):115-121.
- doi: 10.4196/kjpp.2009.13.2.115
Functional defects in mitochondria are involved in the induction of cell death in cancer cells. We assessed the toxic effect of camptothecin against the human cervical and uterine tumor... -
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- The Expression of Bcl-2, Bax, Cytochrome C and Caspase-3 in Camptothecin-Induced Apoptosis of Mouse 3T3 Fibroblasts
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Ahn YJ, Lee MS, Kang G
- KMID: 2073723
- Korean J Pathol.
- 2002 Apr;36(2):71-76.
BACKGROUND: Camptothecin (CPT), which has been used for cancer treatment and apoptosis as an inhibitor of DNA topoisomerase I. We investigated the possibility that camptothecin induces anti-appoptotic bcl-2 and pro-apoptotic... -
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- Camptothecin-nduced Apoptosis in Gastric Cancer Cell Lines: Involvement of Bcl-
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Cha YJ, Min YD, Choi CH
- KMID: 1940174
- J Korean Surg Soc.
- 1998 Dec;55(6):800-808.
BACKGROUND: Apoptosis can be induced by various anticancer agents. Resistance to apoptosis may play an important role in tumors refractory to chemotherapy. The authors investigated both the induction of apoptosis... -
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- Efficacy and Safety of FOLFIRI as Second-line Chemotherapy in Advanced Gastric Cancer
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Park SC, Chun HJ
- KMID: 2373304
- Korean J Gastroenterol.
- 2015 Jul;66(1):1-4.
- doi: 10.4166/kjg.2015.66.1.1
No abstract available. -
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- Rapidly Growing Interval Colon Cancer
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Kim JH, Park MI
- KMID: 2373231
- Korean J Gastroenterol.
- 2015 May;65(5):326-329.
- doi: 10.4166/kjg.2015.65.5.326
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- A Case of Typhlitis Developed after Chemotherapy with Irinotecan and Cisplatin in a Patient with Small Cell Lung Carcinoma
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Ji EH, Kim YM, Kim SJ, Yeom SJ, Ha SE, Kang HH, Kang JY, Lee SH, Moon HS
- KMID: 2050683
- Tuberc Respir Dis.
- 2012 Nov;73(5):288-291.
- doi: 10.4046/trd.2012.73.5.288
Typhlitis is a necrotizing colitis that usually occurs in neutropenic patients and develops most often in patients with hematologic malignancies such as leukemia and lymphoma. Typhlitis may proceed to bowel... -
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- Measurement of apoptosis using M30 in culture media of cell lines treated with anti-cancer agents
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Park SH, Kwack HS, Ryu KS, Lee Y, Han KT
- KMID: 2273871
- Korean J Obstet Gynecol.
- 2010 May;53(5):401-409.
- doi: 10.5468/kjog.2010.53.5.401
OBJECTIVE: We investigated a possible use of the induced apoptosis as a biomarker in the cells and their media treated with commonly used anti-cancer agents in gynecologic malignancies. METHODS: After treatments... -
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- Anticancer effect of CKD-602(belotecan, camtobell(R)) on the oral cancer cell lines
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Yun PY, Ok YJ, Myoung H, Lee JH, Kim MJ
- KMID: 2058808
- J Korean Assoc Oral Maxillofac Surg.
- 2005 Feb;31(1):7-12.
PURPOSE: CKD-602, a newly developed water-soluble campthotecin analogue, is a anticancer agent which act as a DNA topoisomerase I inhibitor. CKD-602 is known as more potent and tolerable agent. The... -
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- Relationship between the Expression of Apoptosis-Related Proteins and Chemosensitivity in Gastric Cancer Cell Lines
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Kim KJ, Min YD, Jeong KH, Choi CH
- KMID: 2325082
- J Korean Surg Soc.
- 1999 Dec;57(Suppl):967-975.
BACKGROUND: There has been a growing realization that a variety of anticancer drugs can induce apoptotic cell death. In the present study, an attempt was made to investigate the responsiveness... -
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- Recent Advances in Chemotherapy of Gastric Cancer
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Park SH, Lee SI
- KMID: 2264289
- Korean J Med.
- 2012 Apr;82(4):417-426.
Surgery is the best and the only treatment modality for cure if a patient has resectable gastric cancer. The outcome can be improved by a strategy of perioperative (neoadjuvant or... -
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- Adjuvant Chemotherapy in Colon Cancer
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Cho SH
- KMID: 2263448
- Korean J Med.
- 2012 Sep;83(3):297-304.
Colorectal cancer represents a major public health problem in worldwide including Korea. According to the National Cancer Registry, colon cancer is the third most common cancer and the forth leading... -
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- Detection of chemosensitivity using K18-Asp(396) (M30) antibody in HeLa and OVCAR-3 cell lines treated with anticancer agents
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Song MK, Park SH, Kwack HS, Ryu KS, Han KT
- KMID: 2077959
- Korean J Obstet Gynecol.
- 2010 Jan;53(1):43-52.
- doi: 10.5468/kjog.2010.53.1.43
OBJECTIVE: The aim of this study was to detect the levels of M30-antigens as a biomarker of apoptosis in cells and their culture media after treatments with anticancer drugs as... -
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- The Expression of Multidrug Resistance-Associated Protein (MRP) and the Chemosensitivity in Gastric Cancer Cell Lines
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Chang YK, Choi CH, Cha YJ, Rha HS, Jeong JH, Jang JH, Min YD
- KMID: 2209281
- J Korean Surg Soc.
- 2000 Jun;58(6):752-759.
PURPOSE: Gastric cancer cells may show resistance to various chemotherapeutic agents. The ability of cancer cells to become drug resistant is thought to be a cause of chemotherapy failure. Recent... -
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- Cytotoxic effects of Belotecan in the cervical cancer cell lines
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Jeon CR, Lee KH, Oh EK, Kim CJ, Park TC, Park JS
- KMID: 2273177
- Korean J Obstet Gynecol.
- 2007 Sep;50(9):1223-1232.
OBJECTIVE: In our domestic market, Belotecan (Camptobel(R), chongkeundang, Korea) is newly introduced recently. Belotecan has many advantages of improved water solubility and fewer side effects like severe diarrhea or GI... -
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- Surgical Management of Colorectal Cancer
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Jeong SY
- KMID: 2188333
- J Korean Med Assoc.
- 2010 Jul;53(7):569-581.
- doi: 10.5124/jkma.2010.53.7.569
In Korea, the incidence of colorectal cancer has rapidly increased in both men and women during recent two decades, and now it is the third most common cancer. Deaths related... -
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- Belotecan and Cisplatin Combination Chemotherapy for Previously Untreated Extensive-Disease Small Cell Lung Cancer
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Lee JE, Lee KY, Park HS, Jung SS, Kim JO, Kim SY
- KMID: 2200023
- J Lung Cancer.
- 2010 Jun;9(1):15-19.
- doi: 10.6058/jlc.2010.9.1.15
PURPOSE: Belotecan (Camtobell(R); Chong Keun Dang Co., Seoul, Korea) is a new camptothecin analog that inhibits topoisomerase I. We evaluated the efficacy and toxicity of belotecan combined with cisplatin in... -
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- Chemotherapy of Advanced Gastric Cancer
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Jung JT
- KMID: 2249478
- Korean J Helicobacter Up Gastrointest Res.
- 2013 Sep;13(3):142-146.
- doi: 10.7704/kjhugr.2013.13.3.142
Gastric cancer is a common malignancy worldwide with a high mortality rate. In advanced gastric cancer, combination chemotherapy improves overall survival compared with best supportive care alone. However, there is... -
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- Recent advances in the treatment of patients with colorectal liver metastases
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Nam EM
- KMID: 2259112
- Korean J Med.
- 2010 Aug;79(2):125-132.
Colorectal cancer (CRC) is 2nd to 3rd common cancer and the annual incidence of CRC is increasing in Korea. The liver is the most frequent metastatic site of colorectal cancer... -
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- Intestinal Perforation in Colorectal Cancers Treated with Bevacizumab (Avastin(R))
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Choi YI, Lee SH, Ahn BK, Baek SU, Park SJ, Kim YS, Shin SH
- KMID: 2166016
- Cancer Res Treat.
- 2008 Mar;40(1):33-35.
Bevacizumab is a monoclonal antibody that targets vascular endothelial growth factor (VEGF), and it has shown promise as a clinical agent against metastatic colorectal cancer, and particularly in combination with... -
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