- Calcium homeostasis in diabetes mellitus
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Ahn C, Kang JH, Jeung EB
- KMID: 2412442
- J Vet Sci.
- 2017 Sep;18(3):261-266.
- doi: 10.4142/jvs.2017.18.3.261
Diabetes mellitus (DM) is becoming a lifestyle-related pandemic disease. Diabetic patients frequently develop electrolyte disorders, especially diabetic ketoacidosis or nonketotic hyperglycemic hyperosmolar syndrome. Such patients show characteristic potassium, magnesium, phosphate,... -
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- Endothelin 1 protects HN33 cells from serum deprivation-induced neuronal apoptosis through Ca2+-PKCalpha-ERK pathway
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Park MH, Lee DH
- KMID: 1103592
- Exp Mol Med.
- 2008 Feb;40(1):92-97.
- doi: 10.3858/emm.2008.40.1.92
Endothelins (ETs), which were originally found to be potent vasoactive transmitters, were known to be implicated in nervous system, but the mode of mechanism remains unclear. ETs (ET-1, ET-2, and... -
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- Calcium-influx increases SOD1 aggregates via nitric oxide in cultured motor neurons
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Kim HJ, Im W, Kim S, Kim SH, Sung JJ, Kim M, Lee KW
- KMID: 1090960
- Exp Mol Med.
- 2007 Oct;39(5):574-582.
Familial amyotrophic lateral sclerosis (fALS) is caused by mutations in Cu/Zn-superoxide dismutase (SOD1), and SOD1 aggregation and calcium toxicity are involved in neuronal death. However, the effect of altered calcium... -
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- Calcium cycling proteins in heartfailure, cardiomyopathy and arrhythmias
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Minamisawa S, Sato Y, Cho MC
- KMID: 1097100
- Exp Mol Med.
- 2004 Jun;36(3):193-203.
A growing body of evidence, including studies using genetically engineered mouse models, has shown that Ca2+ cycling and Ca2+ -dependent signaling pathways play a pivotal role in cardiac hypertrophy and... -
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- Propofol and Aminophylline Antagonize Each Other During the Mobilization of Intracellular Calcium in Human Umbilical Vein Endothelial Cells
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Son HJ, Lim YC, Ha KS, Kang SS, Cheong IY, Lee SJ, Park SW, Hwang BM
- KMID: 1714047
- J Korean Med Sci.
- 2010 Aug;25(8):1222-1227.
- doi: 10.3346/jkms.2010.25.8.1222
This study examined whether propofol and aminophylline affect the mobilization of intracellular calcium in human umbilical vein endothelial cells. Intracellular calcium was measured using laser scanning confocal microscopy. Cultured and... -
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- Atrial natriuretic peptide induces rat peritoneal mast cell activation by cGMP-independent and calcium uptake-dependent mechanism
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Chai OH, Lee YH, Han EH, Kim HT, Lee MS, Song CH
- KMID: 755096
- Exp Mol Med.
- 2000 Dec;32(4):179-186.
Atrial natriuretic peptide (ANP), a 28 amino acid basic polypeptide, is known to induce histamine release from human and rat mast cells in vitro and cause a wheel... -
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- Calcium overload is essential for the acceleration of staurosporine-induced cell death following neuronal differentiation in PC12 cells
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Seo SR, Seo JT
- KMID: 1088602
- Exp Mol Med.
- 2009 Apr;41(4):269-276.
- doi: 10.3858/emm.2009.41.4.030
Differentiation of neuronal cells has been shown to accelerate stress-induced cell death, but the underlying mechanisms are not completely understood. Here, we find that early and sustained increase in cytosolic... -
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- Effect of excitability-inducing material on regenerative Ca++ release of rat ventricular muscle
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Kang DH, Lee YH, Song HJ
- KMID: 1729588
- Yonsei Med J.
- 1991 Sep;32(3):215-222.
- doi: 10.3349/ymj.1991.32.3.215
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- Liquid Heparin Anticoagulant Produces More Negative Bias in the Determination of Ionized Magnesium than Ionized Calcium
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Shin CS, Chang CH, Kim JH
- KMID: 1110741
- Yonsei Med J.
- 2006 Apr;47(2):191-195.
- doi: 10.3349/ymj.2006.47.2.191
The ionized calcium level in blood is known to be falsely decreased when self-prepared liquid heparin anticoagulant is used, due to dilution and binding effects. The effect of liquid heparin... -
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- Na+-Ca2+ exchanger modulates Ca2+ content in intracellular Ca2+ stores in rat osteoblasts
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Jung SY, Park YJ, Park YJ, Cha SH, Lee MZ, Suh CK
- KMID: 756068
- Exp Mol Med.
- 2007 Aug;39(4):458-468.
Na+ -Ca2+ exchanger (NCX) transports Ca2+ coupled with Na+ across the plasma membrane in a bi-directional mode. Ca2+ flux via NCX mediates osteogenic processes, such as formation of extracellular matrix... -
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- Activation of calcium signaling by hepatitis B virus-X protein in liver cells
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Oh JC, Jeong DL, Kim IK, Oh SH
- KMID: 1109320
- Exp Mol Med.
- 2003 Aug;35(4):301-309.
Hepatitis B virus x gene product (HBx) is known to be a transactivator of transcriptional elements that regulate the expression of a variety of genes associated with the growth, differentiation,... -
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- Initiation Site of Ca2+ Entry Evoked by Endoplasmic Reticulum Ca2+ Depletion in Mouse Parotid and Pancreatic Acinar Cells
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Jo H, Byun HM, Lee SI, Shin DM
- KMID: 724110
- Yonsei Med J.
- 2007 Jun;48(3):526-530.
- doi: 10.3349/ymj.2007.48.3.526
PURPOSE: In non-excitable cells, which include parotid and pancreatic acinar cells, Ca(2+) entry is triggered via a mechanism known as capacitative Ca(2+) entry, or store-operated Ca(2+) entry. This process is... -
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- Regulation of GTP-binding state in RalA through Ca2+ and calmodulin
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Park JB
- KMID: 755118
- Exp Mol Med.
- 2001 Mar;33(1):54-58.
RalA GTPase, a member of Ras superfamily proteins, shows alternative forms between the active GTP-binding and the inactive GDP-binding states. Ral-specific guanine nucleotide exchange factor such as RalGDS interacts with... -
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- Acute Modulations in Stratum Corneum Permeability Barrier Function Affect Claudin Expression and Epidermal Tight Junction Function via Changes of Epidermal Calcium Gradient
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Baek JH, Lee SE, Choi KJ, Choi EH, Lee SH
- KMID: 1503920
- Yonsei Med J.
- 2013 Mar;54(2):523-528.
- doi: 10.3349/ymj.2013.54.2.523
Tight junction (TJ) is recognized as a second barrier of the skin. Altered expression of TJ proteins in various skin diseases characterized by the abnormal permeability barrier such as psoriasis... -
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- Molecular identification of Ca(2+)channels in human sperm
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Park JY, Ahn HJ, Gu JG, Lee KH, Kim JS, Kang HW, Lee JH
- KMID: 1109318
- Exp Mol Med.
- 2003 Aug;35(4):285-292.
The acrosome reaction is a Ca(2+)-dependent exocytotic process that is a prerequisite step for fertilization. External calcium entry through voltage-activated Ca(2+)channels is known to be essential in inducing the acrosome... -
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- Calcium sensing receptor forms complex with and is up-regulated by caveolin-1 in cultured human osteosarcoma (Saos-2) cells
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Jung SY, Kwak JO, Kim HW, Kim DS, Ryu SD, Ko CB, Cha SH
- KMID: 755747
- Exp Mol Med.
- 2005 Apr;37(2):91-100.
The calcium sensing receptor (CaSR) plays an important role for sensing local changes in the extracellular calcium concentration ([Ca2+]o) in bone remodeling. Although the function of CaSR is known, the... -
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- Involvement of the Ca2+ signaling pathway in osteoprotegerin inhibition of osteoclast differentiation and maturation
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Fu Y, Gu J, Wang Y, Yuan Y, Liu X, Bian J, Liu ZP
- KMID: 2164523
- J Vet Sci.
- 2015 Jun;16(2):151-156.
- doi: 10.4142/jvs.2015.16.2.151
The purpose of this study was to determine whether the Ca2+ signaling pathway is involved in the ability of osteoprotegerin (OPG) to inhibit osteoclast differentiation and maturation. RAW264.7 cells were... -
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- Transglutaminase 2 inhibits apoptosis induced by calciumoverload through down-regulation of Bax
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Cho SY, Lee JH, Bae HD, Jeong EM, Jang GY, Kim CW, Shin DM, Jeon JH, Kim IG
- KMID: 983956
- Exp Mol Med.
- 2010 Sep;42(9):639-650.
- doi: 10.3858/emm.2010.42.9.063
An abrupt increase of intracellular Ca2+ is observed in cells under hypoxic or oxidatively stressed conditions. The dysregulated increase of cytosolic Ca2+ triggers apoptotic cell death through mitochondrial swelling and... -
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- Phosphorylation of 46-kappa Da protein of synaptic vesicle membranes is stimulated by GTP and Ca2+/calmodulin
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Kim AR, Choi WH, Lee SR, Kim JS, Jeon CY, Kim JI, Kim JB, Lee JY, Kim EG, Park JB
- KMID: 1121097
- Exp Mol Med.
- 2002 Dec;34(6):434-443.
The release of neurotransmitter is regulated in the processes of membrane docking and membrane fusion between synaptic vesicles and presynaptic plasma membranes. Synaptic vesicles contain a diverse set of... -
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- Expression of Neutrophil Gelatinase-Associated Lipocalin in Calcium-Induced Keratinocyte Differentiation
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Lee JH, Kye KC, Seo EY, Lee K, Lee SK, Lim JS, Seo YJ, Kim CD, Park JK
- KMID: 1713465
- J Korean Med Sci.
- 2008 Apr;23(2):302-306.
- doi: 10.3346/jkms.2008.23.2.302
In a previous search for the differentially expressed genes in keratinocyte differentiation, we identified neutrophil gelatinase-associated lipocalin (NGAL) as a calcium- induced gene. In this study, we further verified the... -
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