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Elevation of alul-induced frequencies of chromosomal aberrations and sister chromatid exchanges in CHO cells substituted with 5-bromodeoxyuridine by ammonium sulfate

Choi IJ, Lee IH, Chang SI

  • KMID: 1686827
  • Korean J Anat.
  • 1991 Mar;24(1):61-69.
No abstract available.
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Nickel (II)-induced apoptosis and G2/M enrichment

Lee SH, Kim DK, Seo YR, Woo KM, Kim CS, Cho MH

  • KMID: 1109301
  • Exp Mol Med.
  • 1998 Sep;30(3):171-176.
Treatment with certain DNA-damaging agents induce a complex cellular response comprising pertubation of cell cycle progression and/or apoptosis on proliferating mammalian cells. Our studies were focused on the cellular effects of nickel (II)...
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Cloning and expression of rat liver type glucose transporter and translocation by insulin in Chinese hamster ovary cells

Ahn YH, Yoon DJ, Han GS, Lee BG

The 5'- and 3'-side half of liver type glucose transporter (GLUT2) cDNA was amplified from total RNA or mRNA by reverse transcriptase-polymerase chain reaction (RT-PCR). The amplified 5'-side fragment of...
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Effect of Lithium on Na+/I- Symporter Gene Expression in Rat Thyroid FRTL-5 Cells

Kang HC

  • KMID: 1883376
  • Chonnam Med J.
  • 2000 Sep;36(3):297-306.
Lithium has been reported to alter thyroid function and cause goiter in some patients. To explain the mechanism of lithium action on thyroid iodide (I-) uptake at the molecular level,...
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Characterization of Monoclonal Antibody Specific for Hepatitis C Virus E2 Envelope Protein

Park JS, Lee BY, Chung SI, Min MK

  • KMID: 2204561
  • J Korean Soc Virol.
  • 1997 Mar;27(1):9-17.
Hepatitis C virus (HCV) E2 protein is known to be one of putative envelope proteins. To develop a sensitive detection method for HCV infected tissues and cells, monoclonal antibodys (MAbs)...
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Mouse Fyn induces pseudopodium formation in Chinese hamster ovary cells

An L, Liu S, Zhang W, Zhang Y, Huang Y, Hu X, Chen S, Zhao S

Molecular mechanisms underlying the effects of Fyn on cell morphology, pseudopodium movement, and cell migration were investigated. The Fyn gene was subcloned into pEGFP-N1 to produce pEGFP-N1-Fyn. Chinese hamster ovary...
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Biological characteristics of Chinese hamster ovary cells transfected with bovine Prnp

Kang SG, Lee DY, Kang ML, Yoo HS

A normal prion protein (PrPc) is converted to a proteaseresistant isoform by an apparent self-propagating activity in transmissible spongiform encephalopathy, a neurodegenerative disease. The cDNA encoding open reading frame (ORF)...
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Development of Proinsulin-secreting Non-endocrine Cell

Yoon DJ, Kim SH, Kim JW, Kim YK, Song YD, Ahn YH

  • KMID: 2331690
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):467-474.
BACKGROUND: Recently, the advent of genetic engineering technics enabled. us to transfer foreign genes of interests into various cells and establish an "artificial b-cells" capable of secreting insulin in response...
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Effect of serum and hydrogen peroxide on the Ca2+/calmodulin-dependent phosphorylation of eukaryotic elongation factor 2(eEF-2) in Chinese hamster ovary cells

Kang KR, Lee SY

  • KMID: 1457530
  • Exp Mol Med.
  • 2001 Dec;33(4):198-204.
Eukaryotic elongation factor eEF-2 mediates regulatory steps important for the overall regulation of mRNA translation in mammalian cells and is activated by variety of cellular conditions and factors. In this...
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The Binding Properties of Glycosylated and Non-Glycosylated Tim-3 Molecules on CD4+CD25+ T Cells

Lee MJ, Heo YM, Hong SH, Kim K, Park S

BACKGROUND: T cell immunoglobulin and mucin domain containing 3 protein (Tim-3) expressed on terminally differentiated Th1 cells plays a suppressive role in Th1-mediated immune responses. Recently, it has been shown...
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Effects of Mannose on Pathogenesis of Acanthamoeba castellanii

Yoo KT, Jung SY

  • KMID: 1792133
  • Korean J Parasitol.
  • 2012 Dec;50(4):365-369.
Acanthamoeba spp. are single-celled protozoan organisms that are widely distributed in the environment. In this study, to understand functional roles of a mannose-binding protein (MBP), Acanthamoeba castellanii was treated with...
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Effect of Iron on Adherence and Cytotoxicity of Entamoeba histolytica to CHO Cell Monolayers

Lee J, Park SJ, Yong TS

Iron is an essential element for almost all living organisms. The possible role of iron for growth, adherence and cytotoxicity of Entamoeba histolytica was evaluated in this study. The absence...
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Expression of HBsAg Containing the PreS1, PreS2 and S in Chinese Hamster Ovary Cell

Kang CY, Baek KM, Lee JW

  • KMID: 1548367
  • Korean J Immunol.
  • 1997 Dec;19(4):429-436.
No abstract available.
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Heterogeneity of TSH Receptor Autoantibodies in Autoimmune Thyroid Disease

Kim WB, Cho BY, Kim KA, Chung JH, Min YK, Lee MS, Lee MK, Kim KW

  • KMID: 2331059
  • J Korean Soc Endocrinol.
  • 1997 Jun;12(2):176-193.
BACKGROUND: It has been known that most of thyroid stimulating antibodies (TSAbs) may interact with epitopes near N-terminal, and thyroid stimulation blocking antibodies (TSBAbs) near C-terminal on the extracellular domain...
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Usefulness of Immunoglobulin Fraction Precipitated with Polyethylene Glycol in Assay for TSH Receptor Antibodies using Chinese Hamster Overy Cells Expressing Human TSH Receptors

Kim WB, Chung HK, Koh CS, Yim CH, Park DJ, Cho BY, Lee HG

  • KMID: 2142203
  • J Korean Soc Endocrinol.
  • 1998 Jun;13(2):167-180.
BACKGROUND: Graves' disease and primary myxedema are thought to be caused by the action of TSH receptor autoantibodies(thyroid stimulating antibody; TSAb & thyroid stimulation blocking antibody; TSBAb). Thus, detection of...
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Establishment and evaluation of a murine alphavbeta3-integrin-expressing cell line with increased susceptibility to Foot-and-mouth disease virus

Zhang W, Lian K, Yang F, Yang Y, Zhu Z, Zhu Z, Cao W, Mao R, Jin Y, He J, Guo J, Liu X, Zheng H

Integrin alphavbeta3 plays a major role in various signaling pathways, cell apoptosis, and tumor angiogenesis. To examine the functions and roles of alphavbeta3 integrin, a stable CHO-677 cell line expressing...
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Osteogenesis by Transfer of Bone Morphogenetic Protein-2 cDNA in Ligamentum Flavum Cells: Approach Toward Tissue Engineering

Moon SH, Kim H, Kwon UH, Won JH, Kim HS, Hahn SB, Lee HM

STUDY DESIGN: In-vitro experiment. OBJECTIVES: To determine the effect of bone morphogenetic protein-2 in the osteogenesis of human ligamentum flavum cells and test the feasibility of gene transfer to these cells. SUMMARY OF...
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Decreasing effect of an anti-Nfa1 polyclonal antibody on the in vitro cytotoxicity of pathogenic Naegleria fowleri

Jeong SR, Kang SY, Lee SC, Song KJ, Im KI, Shin HJ

The nfa1 gene was cloned from a cDNA library of pathogenic Naegleria fowleri by immunoscreening; it consisted of 360 bp and produced a 13.1 kDa recombinant protein (rNfa1) that showed...
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In vitro cytotoxicity of Acanthamoeba spp. isolated from contact lens containers in Korea by crystal violet staining and LDH release assay

Shin HJ, Cho MS, Jung SY, Kim HI, Im KI

In order to observe the cytotoxicity of Acanthamoeba spp., which were isolated from contact lens containers as ethiological agents for the probable amoebic keratitis in Korea, the crystal violet staining...
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Nerve growth factor(NGF) induces mRNA expression of the new transcription factor protein p48ZnF

Heese K, Nagai Y, Sawada T

  • KMID: 1380207
  • Exp Mol Med.
  • 2004 Apr;36(2):130-134.
Apoptosis, the cell's intrinsic death program, plays a crucial role in the regulation of tissue homeostasis, and abnormal inhibition of apoptosis is an indicator of cancer and autoimmune diseases, whereas...
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