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Increased Expression of Brain-derived Neurotrophic Factor in Irritable Bowel Syndrome and Its Correlation With Abdominal Pain (Gut 2012;61:685-694)

Joo YE

  • KMID: 2325983
  • J Neurogastroenterol Motil.
  • 2013 Jan;19(1):109-111.
No abstract available.
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A BDNF Val66Met Polymorphism and Ketamine-induced Rapid Antidepressant Action

Hashimoto

  • KMID: 2134676
  • Clin Psychopharmacol Neurosci.
  • 2012 Apr;10(1):59-60.
No abstract available.
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Brain-Derived Neurotrophic Factor(BDNF) Genetic Polymorphism and the Long-term Outcome of Antidepressant Treatment in Korean Depressive Patients

Koo JW, Lee HY, Paik JW, Kang RH, Lee MS

  • KMID: 1511824
  • Korean J Biol Psychiatry.
  • 2006 Aug;13(3):162-169.
associated with the long-term outcome of the antidepressant treatment. However, further studies with another BDNF polymorphism should be needed.
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196G/A of the Brain-Derived Neurotrophic Factor Gene Polymorphisms Predicts Suicidal Behavior in Schizophrenia Patients

Kim EJ, Kim YK

OBJECTIVE: Brain-derived neurotrophic factor (BDNF) has possible neurobiologic impact on etiology of schizophrenia. We hypothesized that the specific allele or the genotype such as two single nucleotide polymorphisms (SNPs) ,...
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The Meaning of BDNF Level Measured in Blood of Depressed Patients

Lee BH, Kim YK

  • KMID: 2341544
  • J Korean Neuropsychiatr Assoc.
  • 2009 Jul;48(4):203-206.
Brain-derived neurotrophic factor (BDNF) is an important member of the neurotrophic factors, which are critical regulators of the formation and plasticity of neuronal networks. BDNF is abundant in the brain...
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Alterations in Serum BDNF and GDNF Levels after 12 Weeks of Antidepressant Treatment in Female Outpatients with Major Depressive Disorder

Park YM, Lee BH

OBJECTIVE: Some clinical studies have found alterations in the levels of serum brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) after applying antidepressant treatment in patients with...
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Expression of mRNAs for Neurotrophic Factors in Human Neural Stem Cells Derived from Fetal Telencephalon

Yoo YM, Lee U, Kim YJ

  • KMID: 2188881
  • J Korean Neurosurg Soc.
  • 2003 May;33(5):488-494.
OBJECTIVE: Cellular diversity in the mammalian central nervous system is originated from precursor cells present in the neural ectoderm. The multipotent neural stem cells(NSCs) rapidly proliferate to give rise to...
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Neurobiological understanding of suicide

Kim S, Lee KU

Suicide is a complex phenomenon resulting from interactions between individual vulnerabilities and socio-environmental factors. The current review primarily focuses on research into the serotonin system, hypothalamic-pituitary-adrenal axis, neurotrophic factors, lipid...
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An Association Study of the Brain-Derived Neurotrophic Factor Val66Met Gene Polymorphism and Schizophrenia

Lee HY, Kim DJ, Kim YK

  • KMID: 2299945
  • Korean J Biol Psychiatry.
  • 2006 Nov;13(4):267-272.
OBJECTIVES: Schizophrenia is a clinically heterogenous disease with a strong genetic component. Many studies have suggested that brain-derived neurotrophic factor(BDNF) is involved in the pathophysiology of schizophrenia. This study was...
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Expression and Distribution of BDNF (Brain Derived Neurotrophic Factor) in the Rat Hypothalamus

Lee YI, Hyun JK

  • KMID: 2092960
  • Korean J Anat.
  • 2009 Jun;42(2):131-138.
BDNF belongs to the neurotrophin family and important molecular mediator of functional and structural plasticity. The highest levels of BDNF are found in the hippocampus and hypothalamus of the adult...
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Comparative Study of Serum Brain-Derived Neurotrophic Factor in Acute and Chronic Depression

Lee SY, Chung JW, Lim SW, Kim SY, Kim DK

  • KMID: 2287397
  • Korean J Psychopharmacol.
  • 2009 Sep;20(5):254-261.
OBJECTIVE: The aim of this study was to compare the serum brain-derived neurotrophic factor (BDNF) in acute depression with that in chronic depression. METHODS: Eighty subjects who met criteria for...
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The Relationship Between Brain-derived Neurotrophic Factor, Serotonin, Physical Fitness, Energy Expenditure and Exercise Intensity in Children

Kim HJ

  • KMID: 2271021
  • Korean J Obes.
  • 2013 Jun;22(2):107-113.
BACKGROUND: The purpose of this study was to determine the effects of physical activity and fitness on brain nerve growth factor in children. METHOD: Seventy-three subjects were selected from one elementary...
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The Effects of Unilateral Dopaminergic Deafferentation on the Expression of mRNAs of Neurotrophic Factors

Park MK, Kim H, Lee DH

  • KMID: 1957217
  • J Korean Neurol Assoc.
  • 1995 Sep;13(3):425-437.
Recently protective and supportive functions of neurotrophic factors on dopaminergic neurons have been reported. In this study, in situ hybridization histochemistry with "S-labeled oligonucleotide probes for brain-derived factor (BDNF) and...
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Expression of Brain-derived Neurotrophic Factor mRNA in Transient Cerebral Ischemic Model of Gerbil Mouse

Park MK, Koh SB, Park KW, Lee DH

  • KMID: 2342726
  • J Korean Neurol Assoc.
  • 1998 Oct;16(5):689-696.
BACKGROUND: Brain-derlved neurotrophic factors(BDNF) is critically involved in development and maintenance of the central and peripheral nervous system and the expression of its mRNA increases after various insults such as...
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Distribution of Brain-Derived Neurotrophic Factor-Immunoreactive Neurons in the Rat Brain after Colchicine Treatment

Kim JK, Park WH, Cho HJ

  • KMID: 1530630
  • Korean J Anat.
  • 1999 Dec;32(6):801-809.
Widespread brain-derived neurotrophic factor (BDNF) mRNA and protein expression has been detected in the brain. Despite substantial overlap between BDNF mRNA and protein expression, there is general anatomical regions, where...
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Brain-derived Neurotrophic Factor Is Associated with Cognitive Impairment in Elderly Korean Individuals

Lee SJ, Baek JH, Kim YH

OBJECTIVE: Brain-derived neurotrophic factor (BDNF) is a neurotrophin that is widely expressed in the mammalian brain and acts to regulate neuronal survival and influence cognitive processes. The present study measured...
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The Roles of BDNF in the Pathophysiology of Major Depression and in Antidepressant Treatment

Lee BH, Kim YK

  • KMID: 2315908
  • Psychiatry Investig.
  • 2010 Dec;7(4):231-235.
Neurotrophic factors are critical regulators of the formation and plasticity of neuronal networks. Brain-derived neurotrophic factor (BDNF) is abundant in the brain and periphery, and is found in both human...
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Epigenetic Regulation in the Brain after Spinal Cord Injury : A Comparative Study

Park BN, Kim SW, Cho SR, Lee JY, Lee YH, Kim SH

OBJECTIVE: After spinal cord injury (SCI), functional and structural reorganization occurs at multiple levels of brain including motor cortex. However, the underlying mechanism still remains unclear. The current study was...
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Cocaine-induced Psychosis and Brain-derived Neurothrophic Factor in Patients with Cocaine Dependence: Report of Two Cases

Roncero C, Palma-Alvarez RF, Ros-Cucurull E, Barral C, Gonzalvo B, Corominas-Roso M, Casas M, Grau-Lopez L

Brain-derived neurotrophic factor (BDNF) is linked to numerous brain functions. In addition, BDNF alterations contribute to neurological, mental, and addictive disorders. Cocaine dependence has received much attention recently due to...
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Antidepressive Effects of Exercise

Park SC

Exercise is considered as one of the therapeutic options. in many major treatment guidelines for depression In terms of the underlying neurobiological mechanisms, it has been suggested that the antidepressive...
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