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Effect of the combination of metformin and fenofibrate on glucose homeostasis in diabetic Goto-Kakizaki rats

Oh TJ, Shin JY, Kang GH, Park KS, Cho YM

  • KMID: 2154249
  • Exp Mol Med.
  • 2013 Jul;45(7):e30.
Metformin has been reported to increase the expression of the glucagon-like peptide-1 (GLP-1) receptor in pancreatic beta cells in a peroxisome proliferator-activated receptor (PPAR)-alpha-dependent manner. We investigated whether a PPARalpha...
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Effects of decreased cerebral perfusion pressure on cerebral hemodynamics, brain cell membrane function and energy metabolism during the early phase of experimental Escherichia coli meningitis in the newborn piglet

Park WS, Chang YS

In this study, we tested the hypothesis that decreased cerebral perfusion pressure (CPP) induces cerebral ischemia and worsen brain damage in neonatal bacterial meningitis. Meningitis was induced by intracisternal injection...
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Relations between Long-term Glycemic Control and Postoperative Wound and Infectious Complications after Total Knee Arthroplasty in Type 2 Diabetics

Han HS, Kang SB

BACKGROUND: The authors examined whether poor preoperative glucose control, as indicated by the hemoglobin A1c (HbA1c) level of more than 8%, is associated with postoperative wound and infectious complications in...
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Relations of Plasma High-Sensitivity C-Reactive Protein to Various Cardiovascular Risk Factors

Ryu SY, Lee YS, Park J, Kang MG, Kim KS

This study was performed to evaluate the relation of high-sensitivity C-reactive protein (hsCRP) with several cardiovascular risk factors such as age, blood pressure, smoking habit and serum lipids, body mass...
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An insulinoma with an aberrant feeder from the splenic artery detected by super-selective arterial calcium stimulation with venous sampling

Moon JH, Kim EK, Khang AR, Kim HC, Jang JY, Cho YM

No abstract available.
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Associations among Body Mass Index, Insulin Resistance, and Pancreatic beta-Cell Function in Korean Patients with New-Onset Type 2 Diabetes

Chung JO, Cho DH, Chung DJ, Chung MY

BACKGROUND/AIMS: We investigated the associations among body mass index (BMI), insulin resistance, and beta-cell function in Korean patients newly presenting with type 2 diabetes. METHODS: In total, 132 patients with new-onset...
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Hypoglycemic effects of vanadium on alloxan monohydrate induced diabetic dogs

Kim JM, Chung JY, Lee SY, Choi EW, Kim MK, Hwang CY, Youn HY

The hypoglycemic effects after oral administration of vanadium have been studied previously in many species such as rats, mice and even humans. However, there has been no prior report on...
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Type B insulin-resistance syndrome presenting as autoimmune hypoglycemia, associated with systemic lupus erythematosus and interstitial lung disease

Kang SM, Jin HY, Lee KA, Park JH, Baek HS, Park TS

We describe an unusual case of systemic lupus erythematosus with pulmonary manifestations presenting as hypoglycemia due to anti-insulin receptor antibodies. A 38-year-old female suffered an episode of unconsciousness and was...
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Differential Effects of High-carbohydrate and High-fat Diet Composition on Muscle Insulin Resistance in Rats

Chun MR, Lee YJ, Kim KH, Kim YW, Park SY, Lee KM, Kim JY, Park YK

This study was conducted to evaluate whether the composition of carbohydrate or fat diet affects insulin resistance by measuring the muscle glucose transport rate. Both high-sucrose and high-starch diet with...
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Repeated dose toxicity of alfa-cypermethrin in rats

Manna S, Bhattacharyya D, Mandal TK, Das S

  • KMID: 1099838
  • J Vet Sci.
  • 2004 Sep;5(3):241-245.
The present study was performed to investigate the subacute effect of alpha-cypermethrin (alpha-CP) in rats. Alfacypermethrin a synthetic pyrethroid insecticide, dissolved in dimethyl sulfoxide (DMSO) and oral LD50 was investigated...
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Diabetic Retinopathy Risk Factors: Plasma Erythropoietin as a Risk Factor for Proliferative Diabetic Retinopathy

Gholamhossein Y, Behrouz H, Asghar Z

PURPOSE: The purpose of this study was to evaluate whether any stage of diabetic retinopathy (DR) is associated with levels of plasma erythropoietin and other plasma parameters. METHODS: It was examined...
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Effect of nicotinamide on early graft failure following intraportal islet transplantation

Jung DY, Park JB, Joo SY, Joh JW, Kwon CH, Kwon GY, Kim SJ

Intraportal islet transplantation (IPIT) may potentially cure Type 1 diabetes mellitus; however, graft failure in the early post-transplantation period presents a major obstacle. In this study, we tested the ability...
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Attitudes and Reported Practice for Obesity Management in Korea After Introduction of Anti-obesity Agents

Park HS, Park JY, Cho HJ

This study aimed to evaluate current clinical assessments and management of obesity in the primary care setting in Korea since anti-obesity agents have become available. A questionnaire was sent to...
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Associations between Hemoglobin Concentrations and the Clinical Characteristics of Patients with Type 2 Diabetes

Chung JO, Cho DH, Chung DJ, Chung MY

BACKGROUND/AIMS: Many studies have demonstrated an association between hemoglobin levels and cardiovascular disease in diabetic patients. The aim of this study was to determine whether there is an association between...
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Association between CDH13 Variants and Cardiometabolic and Vascular Phenotypes in a Korean Population

Lee JH, Shin DJ, Park S, Kang SM, Jang Y, Lee SH

PURPOSE: Although some CDH13 single nucleotide polymorphisms (SNPs) have been shown to be determinants of blood adiponectin levels, the clinical implications of CDH13 variants are not yet completely understood. The...
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A Web-based Health Promotion Program for Patients with Metabolic Syndrome

Kang JS, Kang HS, Jeong Y

  • KMID: 2069899
  • Asian Nurs Res.
  • 2014 Mar;8(1):82-89.
PURPOSE: The population of metabolic syndrome is increasing in Korea. The prevalence is related to lifestyle, such as lack of physical activity and irregular diet. Most patients with metabolic syndrome...
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The protective effect of Amomum xanthoides extract against alloxan-induced diabetes through the suppression of NFkappaB activation

Park BH, Park JW

  • KMID: 1085741
  • Exp Mol Med.
  • 2001 Jun;33(2):64-68.
This study was undertaken to investigate the preventive mechanism of Amomum xanthoides extract against the development of alloxan-induced diabetics of mice. Pretreatment of mice with A. xanthoides extract via intraperitoneum...
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Identifying Subjects with Insulin Resistance by Using the Modified Criteria of Metabolic Syndrome

Hsieh CH, Pei D, Hung YJ, Kuo SW, He CT, Lee CH, Wu CZ

The objectives of this cohort analysis were to explore the relationship between insulin resistance (IR) and the criteria for metabolic syndrome (MetS) and to evaluate the ability to detect IR...
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Effects of MK-801 (dizocilpine) on Brain Cell Membrane Function and Energy Metabolism in Experimental Escherichia coli Meningitis in the Newborn Piglet

Ko SY, Shim JW, Kim SS, Kim MJ, Chang YS, Park WS, Shin SM, Lee MH

We evaluated the efficacy of non-competitive N-methyl-D-aspartate receptor antagonist MK-801 (dizocilpine) as an adjuvant therapy in experimental neonal bacterial meningitis. Meningitis was induced by injecting 10(6) colony forming units of...
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The Effect of Pertussis Vaccine and Cyclosporin on Streptozotocin Induced Diabetic Rats

Kim DH

The injection of streptozotocin(stz) at a high dose (60 mg/kg) into young male rats produces direct beta cell destruction and leads to insulin dependent diabetes (IDD). In contrast the injection...
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