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Sensory and motor axons are different: implications for neurological disease

Burke D, Howells J, Kiernan MC

Using threshold tracking, differences have been established between large myelinated sensory and α motor axons in humans. Major differences are that sensory axons are relatively depolarised at rest such that...
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Distribution of Peripherin Immunoreactive Axons in Rat Molar Pulp

Kim TH, Bae YC, Yang ES

Dental pulp is innervated mostly by unmyelinated axons and small myelinated axons. These axons are implicated pain transmission and contain various neurotransmitters and receptors. However, little information, so far, is...
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Morphometric Studies of the Effects of Capsaicin on the Lissauer's tract of the Adult Rats

Lee WT, Cho KH, Lee DJ, Lee JE, Park KA

  • KMID: 1530299
  • Korean J Anat.
  • 1998 Dec;31(6):971-980.
Until recently the neurotoxic effects of capsaicin to adult animals were thought to be limited to the peripheral nervous system. Several reports suggest the possibility of central nervous system changes...
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Effects of Fresh and Degenerated Autogenous Nerve Graft in Segmental Defect of Sciatic Nerve of Rabbit

Park JB, Lee MH, Rhee SK

  • KMID: 2336074
  • J Korean Orthop Assoc.
  • 1998 Jun;33(3):885-891.
The potential for nerve regeneration and recovery of its function exists in the presence of a suitable pathway for regenerating axon and endoneurial tube can serve as nerve conduit for...
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Morphological Analysis of the Myelinated Parent Axons that Innervate Rat Upper Molar Pulps in the Trigeminal Ganglion

Paik SK, Kim JH, Kim TH, Bae YC

Previous studies suggested that myelinated axons innervating rat molar pulps undergo morphological changes in their peripheral course. However, little information is available on the morphological feature of the parent axons...
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Distribution of Cold Receptor Transient Receptor Potential Melastatin 8-Immunopositive Axons in the Mouse Dental Pulp and Periodontal Tissue

Kim TH, Lee JS, Kim YS, Bae YC

Transient receptor potential melastatin 8 (TRPM8) plays a crucial role in innocuous cool sensation, acute cold pain and cold-induced hyperalgesia during pathologic conditions. To help understand TRPM8-mediated cold perception in...
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Demyelination of neurofilament protein 200 immune positive never fibers in human pulp

Jang JW, Choi SY, Kwon DG, Bae YC, Kim CS, Lee SH

  • KMID: 2328500
  • J Korean Assoc Oral Maxillofac Surg.
  • 2010 Oct;36(5):360-365.
INTRODUCTION: Mammalian tooth pulp is densely innervated by sensory nerves that are mostly C fibers and A delta fibers. However, there is evidence suggesting that many unmyelinated axons in the...
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Ultrastructural Localization of Dopaminergic Receptors in the Amygdala of Rat

Lee HL

The present study was performed to identify the dopaminergic receptor sites in rat amygdala. Identification of the receptor sites at ultrastructrual level has been done by autoradiography after cerebral ventricular...
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Normal data on axonal excitability in Koreans

Lee JY, Yu JH, Pyun SY, Ryu S, Bae JS

BACKGROUND: Automated nerve excitability testing is used to assess various peripheral neuropathies and motor neuron diseases. Comparing these excitability parameters with normal data provides information regarding the axonal excitability properties...
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Localized Paroxysmal Pruritus in Multiple Sclerosis

Yoo JH, Kim HS, Kang DS, Chung KY

  • KMID: 1863734
  • Korean J Dermatol.
  • 2000 Mar;38(3):410-412.
Paroxysmal itching is a rare symptom in multiple sclerosis and it was first reported in 1975 by Osterman and Westerberg. It has been suggested that paroxysmal itching may be due to the...
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Responses of the Nociceptive Axons to the Inflammatory Mediators and Tumor Necrosis Factor-alpha

Lee JR, Park SC, Leem JG, Bove GM

BACKGROUND: Following musculoskeletal injuries, axons are exposed to tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. Exposure of axons to TNF-alpha and complete Freund's adjuvant (CFA) can cause hyperalgesia...
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Palisaded Encapsulated Neuroma

Lee SW, Yi JY, Cho BK, Houh W, Kim TY, Song KY

Palisaded encapsulated neuroma (PEN) is a distinctive benign cutaneous tumor that was first described by Reed et al. in 1972. We have recently experienced two cases of PEN. Clinically, these lesions...
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Sensory Axon Regeneration: A Review from an in vivo Imaging Perspective

Han SB, Kim H, Skuba A, Tessler A, Ferguson T, Son YJ

Injured primary sensory axons fail to regenerate into the spinal cord, leading to chronic pain and permanent sensory loss. Re-entry is prevented at the dorsal root entry zone (DREZ), the...
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Experimental Study on Nerve Regeneration Using Reversed Vascularized Nerve Graft

Kim HJ

The rationale for the use of vascularized nerve graft is based on the premise that a vascularized graft may provide more demyelination within the graft and subsequently more rapid regrowth...
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Axon Diameter in Normal Human Optic Nerve

Jun BK, Kim DS, Ko MK

  • KMID: 2206023
  • J Korean Ophthalmol Soc.
  • 2001 Jul;42(7):1088-1095.
PURPOSE: The morphometric change of optic nerve axons is one of the parameters for evaluating the optic nerve function in pathologic conditions such as optic neuritis, anterior optic neuropathy, glaucomatous...
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Schwann Cells Enhance Penetration of Regenerated Axons into Three-Dimensional Microchannels

Liu C, Kray J, Chan C

Nerve regeneration after injury requires proper axon alignment to bridge the lesion site and myelination to achieve functional recovery. Transplanted scaffolds with aligned channels, have been shown to induce axon...
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HISTOPATHOLOGIC FINDINGS OF THE DEGENERATED INFERIOR ALVEOLAR NERVES RESECTED DUE TO REFRACTORY TRIGEMINAL NEURALGIA

Kim MR, Sung MH, Koo HS

  • KMID: 2005922
  • J Korean Assoc Oral Maxillofac Surg.
  • 1997 Nov;23(4):656-667.
This is to report the histo-pathologic findings of the degenerated inferior alveolar nerves(IAN) causing uncontrollable neuralgia persisted for over 3 years. The patients had sufferred from frequent attack of unbearable...
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The Role of Axonopathy in Parkinson's Disease

O'Malley K

New genetic and environmental studies of Parkinson's disease have revealed early problems in synaptic function and connectivity indicating that axonal impairment may be an important hallmark in this disorder. Since...
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An Experimental Study of Local Anesthetic Injection Injury to Peripheral Nerves

Lee KC, Rim HS, Song YK, Kim TY, Yun JS

Injury to a peripheral nerve due to a drug injection is of particular concern, because of both its clinical and medicolegal implications. Among numerous agents, local anesthetic solutions are most...
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Histologic changes of the inferior alveolar nerve according to the amount of the mandibular lengthening in rabbits

Kim KY, Ryu SY

  • KMID: 2184178
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 1998 Aug;20(3):251-256.
The purpose of this study was to evaluate the histologic change of the inferior alveolar nerve according to distraction amount following mandibular lengthening. Seven rabbits weighing about 2 kg were...
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