- Autophagy in the placenta
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Oh SY, Roh CR
- KMID: 2378586
- Obstet Gynecol Sci.
- 2017 May;60(3):241-259.
- doi: 10.5468/ogs.2017.60.3.241
Autophagy is an evolutionarily conserved catalytic process by which cytoplasmic components including damaged macromolecules and organelles are degraded. The role of autophagy includes adaptive responses to nutrition deprivation or intracellular... -
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- Herpesviral Interaction with Autophagy
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Liang C
- KMID: 2168649
- J Bacteriol Virol.
- 2011 Dec;41(4):213-223.
- doi: 10.4167/jbv.2011.41.4.213
Autophagy constitutes a major catabolic hub for the quality control of intracellular entities of eukaryotic cells, and is emerging as an essential part of the host antiviral defense mechanism. However,... -
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- Interplay Between Primary Cilia and Autophagy and Its Controversial Roles in Cancer
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Ko JY, Lee EJ, Park JH
- KMID: 2455087
- Biomol Ther.
- 2019 Jul;27(4):337-341.
- doi: 10.4062/biomolther.2019.056
Primary cilia and autophagy are two distinct nutrient-sensing machineries required for maintaining intracellular energy homeostasis, either via signal transduction or recycling of macromolecules from cargo breakdown, respectively. Potential correlations between... -
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- Role of Autophagy in the Control of Cell Death and Inflammation
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Lee MS
- KMID: 2167991
- Immune Netw.
- 2009 Feb;9(1):8-11.
- doi: 10.4110/in.2009.9.1.8
There is mounting evidence that autophagy is involved in diverse physiological and pathological processes that have immense relevance in human development, diseases and aging. Immunity and inflammation are not exceptions.... -
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- Autophagy as an Innate Immune Modulator
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Oh JE, Lee HK
- KMID: 2150764
- Immune Netw.
- 2013 Feb;13(1):1-9.
- doi: 10.4110/in.2013.13.1.1
Autophagy is a fundamental cellular process in eukaryotic cells for maintaining homeostasis by degrading cellular proteins and organelles. Recently, the roles of autophagy have been expanded to immune systems, which... -
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- The Role of Autophagy in the Pathogenesis of Atherosclerosis
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Hur SK, Park SH, Oh GT
- KMID: 2328833
- J Lipid Atheroscler.
- 2016 Jun;5(1):1-10.
- doi: 10.12997/jla.2016.5.1.1
Autophagy is a life-sustaining process by which cytoplasmic constituents are segregated in double-lipid bilayer membrane vesicles and undergo degradation into lysosomes. In recent studies, the basal autophagy is an indispensable... -
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- Why is autophagy important in human diseases?
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Jing K, Lim K
- KMID: 1120124
- Exp Mol Med.
- 2012 Feb;44(2):69-72.
- doi: 10.3858/emm.2012.44.2.028
The process of macroautophagy (referred to hereafter as autophagy), is generally characterized by the prominent formation of autophagic vesicles in the cytoplasm. In the past decades, studies of autophagy have... -
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- Autophagy in Innate Recognition of Pathogens and Adaptive Immunity
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Oh JE, Lee HK
- KMID: 1120188
- Yonsei Med J.
- 2012 Mar;53(2):241-247.
- doi: 10.3349/ymj.2012.53.2.241
Autophagy is a specialized cellular pathway involved in maintaining homeostasis by degrading long-lived cellular proteins and organelles. Recent studies have demonstrated that autophagy is utilized by immune systems to protect... -
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- Autophagy and cancer
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Choi KS
- KMID: 1120129
- Exp Mol Med.
- 2012 Feb;44(2):109-120.
- doi: 10.3858/emm.2012.44.2.033
Basal autophagy plays a critical role in maintaining cellular homeostasis and genomic integrity by degrading aged or malfunctioning organelles and damaged or misfolded proteins. However, autophagy also plays a complicated... -
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- Curcumin-Induced Autophagy Augments Its Antitumor Effect against A172 Human Glioblastoma Cells
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Lee JE, Yoon SS, Moon EY
- KMID: 2456223
- Biomol Ther.
- 2019 Sep;27(5):484-491.
- doi: 10.4062/biomolther.2019.107
Glioblastoma is the most aggressive common brain tumor in adults. Curcumin, from Curcuma longa, is an effective antitumor agent. Although the same proteins control both autophagy and cell death, the... -
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- Autophagy in neutrophils
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Shrestha S, Lee JM, Hong CW
- KMID: 2466564
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):1-10.
- doi: 10.4196/kjpp.2020.24.1.1
Autophagy is a highly conserved intracellular degradation and energy-recycling mechanism that contributes to the maintenance of cellular homeostasis. Extensive researches over the past decades have defined the role of autophagy... -
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- miR-Let7A Modulates Autophagy Induction in LPS-Activated Microglia
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Song J, Oh Y, Lee JE
- KMID: 2165545
- Exp Neurobiol.
- 2015 Jun;24(2):117-125.
- doi: 10.5607/en.2015.24.2.117
Microglia regulate the secretion of various immunomediators in central nervous system diseases. Microglial autophagy is the crucial process for cell's survival and cytokine productions. Recent studies have reported that several... -
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- Nutritional Status and Cardiac Autophagy
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Ahn J, Kim J
- KMID: 2280739
- Diabetes Metab J.
- 2013 Feb;37(1):30-35.
- doi: 10.4093/dmj.2013.37.1.30
Autophagy is necessary for the degradation of long-lasting proteins and nonfunctional organelles, and is activated to promote cellular survival. However, overactivation of autophagy may deplete essential molecules and organelles responsible... -
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- The Interplay between Autophagy and Aging
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Pyo JO, Yoo SM, Jung YK
- KMID: 1965979
- Diabetes Metab J.
- 2013 Oct;37(5):333-339.
- doi: 10.4093/dmj.2013.37.5.333
Numerous studies have established a link between autophagy and aging; however, the relationship has not been clearly defined. Aging is a very complex process caused by the accumulation of various... -
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- Molecules and their functions in autophagy
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Pyo JO, Nah J, Jung YK
- KMID: 1120125
- Exp Mol Med.
- 2012 Feb;44(2):73-80.
- doi: 10.3858/emm.2012.44.2.029
Autophagy is a self-degradation system of cellular components through an autophagosomal-lysosomal pathway. Over the last 15 yr, yeast genetic screens led to the identification of a number of genes involved... -
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- Autophagy Inhibition Promotes Quercetin Induced Apoptosis in MG-63 Human Osteosarcoma cells
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Park SJ, Yu SB, Kim YH, Kim IR, Park HR, Park BS
- KMID: 1827457
- Int J Oral Biol.
- 2015 Jun;40(2):85-91.
- doi: 10.11620/IJOB.2015.40.2.085
Quercetin is a natural flavonoid phytochemical that is extracted from various plants. Having an advantages due to its varied biological properties, such as anti-inflammatory, anti-viral, anti-oxidant, and anti-cancer effects, quercetin... -
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- Role of Autophagy in the Control of Body Metabolism
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Quan W, Lee MS
- KMID: 1805938
- Endocrinol Metab.
- 2013 Mar;28(1):6-11.
- doi: 10.3803/EnM.2013.28.1.6
Autophagy plays a crucial role in the maintenance of cellular nutrient balance and the function of organelles such as mitochondria or the endoplasmic reticulum, which are important in intracellular metabolism,... -
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- Autophagy in Mycobacterium abscessus Infection
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Subhadra B, Choi CH
- KMID: 2392960
- J Bacteriol Virol.
- 2017 Sep;47(3):122-131.
- doi: 10.4167/jbv.2017.47.3.122
Autophagy is a self-degradative process that removes misfolded or aggregated proteins, clears damaged organelles, as well as eliminates intracellular pathogens playing a role in innate immunity. Mycobacterium abscessus (M. abscessus)... -
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- Regulatory Role of Autophagy in Globular Adiponectin-Induced Apoptosis in Cancer Cells
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Nepal S, Park PH
- KMID: 2380314
- Biomol Ther.
- 2014 Sep;22(5):384-389.
- doi: 10.4062/biomolther.2014.021
Adiponectin, an adipokine predominantly secreted from adipose tissue, exhibits diverse biological responses, including metabolism of glucose and lipid, and apoptosis in cancer cells. Recently, adiponectin has been shown to modulate... -
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- Autophagy and bacterial infectious diseases
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Yuk JM, Yoshimori , Jo EK
- KMID: 1120128
- Exp Mol Med.
- 2012 Feb;44(2):99-108.
- doi: 10.3858/emm.2012.44.2.032
Autophagy is a housekeeping process that maintains cellular homeostasis through recycling of nutrients and degradation of damaged or aged cytoplasmic constituents. Over the past several years, accumulating evidence has suggested... -
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