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Involvement of tumor necrosis factor receptor superfamily (TNFRSF) members in the pathogenesis of inflammatory diseases

Kwon B, Kim BS, Cho HR, Park JE, Kwon BS

  • KMID: 1088652
  • Exp Mol Med.
  • 2003 Feb;35(1):8-16.
Current therapies for autoimmune diseases are not cures but merely palliatives, aimed at reducing symptoms. For the most part, these treatments provide nonspecific suppression of the immune system and thus...
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Morphological and biochemical analysis of anti-nuclear matrix protein antibodies in human sera

Yu E, Lee H, Oh W, Yu B, Moon H, Lee I

Autoimmune sera have been used in the diagnosis of autoimmune diseases as well as the analysis of nuclear substructures. In an attempt to study the biological characteristics of the nuclear...
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Defects in the differentiation and function of bone marrow-derived dendritic cells in non-obese diabetic mice

Lee M, Kim AY, Kang Y

Due to their high immunostimulatory ability as well as the critical role they play in the maintenance of self-tolerance, dendritic cells have been implicated in the pathogenesis of autoimmune diseases....
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Autoimmune Hemolytic Anemia in a Patient with Primary Ovarian Non-Hodgkin's Lymphoma

Jung CK, Park JS, Lee EJ, Kim SH, Kwon HC, Kim JS, Roh MS, Yoon SK, Kim KH, Han JY, Kim HJ

The primary ovarian lymphoma is a rare disease with poor prognosis. The incidence of autoimmune hemolytic anemia in patients with non-Hodgkin's lymphoma is estimated at 3%. However, a substantial portion...
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Direct Detection of Reactive Nitrogen Species in Experimental Autoimmune Uveitis

Bae SR, Wu GS, Sevanian A, Schultz BE, Zamir E, Rao NA

PURPOSE: Demonstrate unequivocally the generation of nitric oxide in experimental autoimmune uveoretinitis by electron spin resonance spectroscopy (ESR) using ferrous iron complex of N-methyl-D-glucamine dithiocarbamate, (MGD)2-Fe2+, as a spin...
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Anti-Heparin-Platelet Factor 4 Antibody is a Risk Factor for Vascular Access Obstruction in Patients Undergoing Hemodialysis

Lee EY, Hwang KY, Yang JO, Hong SY

Since heparin is an anticoagulant commonly used in hemodialysis and the patients on hemodialysis are repeatedly exposed to heparin, heparin may be the cause of the development of heparin-dependent antibodies...
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Immunopathogenesis of experimental melanin-protein induced uveitis

Kim HS, Lee EH, Kim-Yoon S, Joo CK

The etiology of uveitis, a general term for inflammatory disorders of the uveal tract, has not been clarified. The purpose of this study is to investigate the immunopathogenesis during experimental...
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