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The Association between Asthma and Invasive Pneumococcal Disease: A Nationwide Study in Korea

Kwak BO, Choung JT, Park YM

The purpose of this study was to investigate the association between asthma and invasive pneumococcal disease (IPD) in Korea. A retrospective population-based cohort study was conducted using the Korean Health...
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A Case of IgG4-Related Disease with Bronchial Asthma and Chronic Rhinosinusitis in Korea

Lee YS, Cho HJ, Yoo HS, Shin YS, Park HS

IgG4-related disease (IgG4-RD) is characterized by a systemic involvement of tumor-like lesions with IgG4-positive plasmacytes. We experienced a case of IgG4-RD developed in a patient with bronchial asthma (BA) and...
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Role of circulating immune complex in aspirin-sensitive asthma

Park HS, Nahm DH

  • KMID: 759054
  • Korean J Intern Med.
  • 1998 Feb;13(1):51-55.
BACKGROUND & OBJECTIVES: The pathogenic mechanism of aspirin-sensitive asthma (ASA-BA) remains to be further defined. To evaluate the role of circulating immune complex (CIC) in ASA-BA. SUBJECTS & METHODS: We...
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IL-12-STAT4-IFN-gamma axis is a key downstream pathway in the development of IL-13-mediated asthma phenotypes in a Th2 type asthma model

Kim YS, Choi SJ, Choi JP, Jeon SG, Oh SY, Lee BJ, Gho YS, Lee CG, Zhu Z, Elias JA, Kim YK

IL-4 and IL-13 are closely related cytokines that are produced by Th2 cells. However, IL-4 and IL-13 have different effects on the development of asthma phenotypes. Here, we evaluated downstream...
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Associations of Moderate to Severe Asthma with Obstructive Sleep Apnea

Byun MK, Park SC, Chang YS, Kim YS, Kim SK, Kim HJ, Chang J, Ahn CM, Park MS

PURPOSE: This study aimed to evaluate the correlation between associating factors of moderate to severe asthma with obstructive sleep apnea (OSA). MATERIALS AND METHODS: One hundred and sixty-seven patients who visited...
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The Impact of Smoking on Clinical and Therapeutic Effects in Asthmatics

Jang AS, Park JS, Lee JH, Park SW, Kim DJ, Uh ST, Kim YH, Park CS

Smoking is associated with poor symptom control and impaired therapeutic responses in asthma. A total of 843 patients with asthma were recruited. The patients received treatment for 1 yr according...
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IgE binding patterns to German cockroach whole body extract in Korean atopic asthmatic children

Lee SY, Lee DS, Kim KE, Jeaung BJ, Lee KY

It is widely known that the cockroach is an inhalant allergen in atopic asthma and allergic rhinitis. Even though Bla g I and Bla g II are considered as the...
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Immunoglobulin G Subclass Deficiencies in Adult Patients with Chronic Airway Diseases

Kim JH, Park S, Hwang YI, Jang SH, Jung KS, Sim YS, Kim CH, Kim C, Kim DG

Immunoglobulin G subclass deficiency (IgGSCD) is a relatively common primary immunodeficiency disease (PI) in adults. The biological significance of IgGSCD in patients with chronic airway diseases is controversial. We conducted...
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Availability of Preoperative Systemic Steroids on Endoscopic Sinus Surgery for Chronic Rhinosinusitis with Nasal Polyposis

Hong SJ, Lee JK, Lee HS, Lee JY, Pyo JS, Lee KC

PURPOSE: To analyze the outcome of endoscopic sinus surgery (ESS) after preoperative systemic steroid (PSS) treatment for chronic rhinosinusitis (CRS) with nasal polyposis (NP) and to investigate and compare clinicopathological...
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Clinical Features of Eosinophilic Bronchitis

Joo JH, Park SJ, Park SW, Lee JH, Kim DJ, Uh ST, Kim YH, Park CS

  • KMID: 1758675
  • Korean J Intern Med.
  • 2002 Mar;17(1):31-37.
BACKGROUND: Eosinophilic inflammation of the airway is usually associated with airway hyper-responsiveness in bronchial asthma. However, there is a small group of patients which has the eosinophilic inflammation in the...
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Risk Factors of Acoustic Neuroma: Systematic Review and Meta-Analysis

Chen M, Fan Z, Zheng X, Cao F, Wang L

PURPOSE: Many epidemiological studies have investigated environmental risk factors for the development of acoustic neuroma. However, these results are controversial. We conducted a meta-analysis of case-control studies to identify any...
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Regulation of pro-inflammatory responses by lipoxygenases via intracellular reactive oxygen species in vitro and in vivo

Kim SY, Kim TB, Moon KA, Kim TJ, Shin D, Cho YS, Moon HB, Lee KY

Reactive oxygen species (ROS) performs a pivotal function as a signaling mediator in receptor-mediated signaling. However, the sources of ROS in this signaling have yet to be determined, but may...
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Eosinophil Inflammation of Nasal Polyp Tissue: Relationships with Matrix Metalloproteinases, Tissue Inhibitor of Metalloproteinase-1, and Transforming Growth Factor-beta1

Park HS, Kim SS, Kim HA, Suh YJ, Lee SK, Nahm DH, Lee YM

Eosinophil and mast cell infiltrations are consistent findings in nasal polyp tissue. Previous studies have shown that matrix metalloproteinases (MMPs) may be involved in eosinophil infiltration in airway mucosa of...
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