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Association with inflammatory cells and apolipoproteins to the progression of atherosclerosis

Eo HS, Lee KB, Kim AK, Kim MH, Kim DH, Kim DI

PURPOSE: Inflammatory cells are known to be associated with the progression of atherosclerosis and plaque rupture. However, the relation to inflammatory cells and apolipoproteins on the progression of atherosclerosis is...
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Apolipoprotein E Polymorphism in Patients with Ischemic Cerebrovascular Disease

Park MH, Koh SB, Kim BJ, Park MK, Park KW, Lee DH

  • KMID: 2188674
  • J Korean Geriatr Soc.
  • 2001 Jun;5(2):151-158.
BACKGROUND: The possible role of apolipoprotein E (APOE for gene, apoE for protein) allele in atherosclerotic diseases is not clearly understood. For the putative role of APOE genotypes, we examined...
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Apolipoprotein E, Cholesterol, and Cognitive Decline in Patients with Alzheimer's disease

Kim JM, Son EJ, Shin SM, Oh BJ, Ha HW

  • KMID: 2342945
  • J Korean Neurol Assoc.
  • 2002 Mar;20(2):124-128.
BACKGROUND: The associations of apolipoprotein E (ApoE) genotypes and cholesterol levels with cognitive decline in Alzheimer's disease (AD) are controversial. The aim of this study is to investigate the individual...
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Polymorphisms of Apolipoprotein B and Apolipoprotein E in Hypobetalipoproteinemic Korean

Kim JH, Lim HS, Kwon OH

  • KMID: 2239628
  • Korean J Lab Med.
  • 2002 Dec;22(6):388-394.
BACKGROUND: Hypobetalipoproteinemia (HBL) is characterized by plasma concentration of lowdensity lipoprotein cholesterol below the fifth percentile in a healthy population. It has been suggested that HBL may be associated with...
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Apolipoprotein E Gene Polymorphism and Plasma Lipid Levels in Male Korean Patients with Chronic Renal Failure

Lee YH, Kim HY, Huh W, Chang SH, Kim YG, Kim DJ, Oh HY

  • KMID: 2254640
  • Korean J Nephrol.
  • 1998 Jul;17(4):583-590.
Accelerated atherosclerosis is not only a frequent complication but also the most common cause of death in patients with chronic renal failure (CRF). Although mechanisms are unclear, disorder of lipid...
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Association of Apolipoprotein E Genotypes with Late-onset Alzheimer's Disease in Korea

Lee YS, Na DL, Kim JW

  • KMID: 2342525
  • J Korean Neurol Assoc.
  • 1996 Jun;14(2):538-542.
Apolipoprotein E-epsilon4(APOE4) is recently known as a susceptibility gene or risk factor associated with late-onset Alzheimer's disease (AD). Association between APOE4 and probable AD was determined in Korean population. Twenty...
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Rapid Apolipoprotein E Genotyping by the Multiplex Amplification Refractory Mutation System

Lee MK, Park AJ

  • KMID: 2089672
  • Korean J Clin Pathol.
  • 2001 Apr;21(2):154-159.
BACKGROUND: Currently, several different apolipoprotein E (apo E) genotyping methods have been developed. The Amplification Refractory Mutation System (ARMS) apo E genotyping, as previously described, requires four separate PCR reactions....
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Rapid Changes in Serum Lipid Profiles during Combination Therapy with Daclatasvir and Asunaprevir in Patients Infected with Hepatitis C Virus Genotype 1b

Chida T, Kawata K, Ohta K, Matsunaga , Ito J, Shimoyama , Yamazaki S, Noritake H, Suzuki T, Suda T, Kobayashi

BACKGROUND/AIMS: Changes in lipid profiles in patients infected with hepatitis C virus (HCV) during direct-acting antiviral therapy have been reported in recent years. However, the clinical aspects of disturbed lipid...
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A Prospective Study on an Association between Apolipoprotein E epsilon4 and Cognitive Change in Community-Dwelling Elders with Alzheimer's Disease

Kang MS, Moon SW

  • KMID: 2250700
  • Korean J Biol Psychiatry.
  • 2013 Sep;20(3):104-110.
OBJECTIVES: The aim of this study was to examine the prospective impact of the apolipoprotein E (APOE) epsilon4 on cognitive performance in the community-dwelling elderly individuals with Alzheimer's disease (AD). METHODS:...
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Differences in Hematological Characteristics, Including Cholesterol and Apolipoprotein B and E, between Hepatitis B Virus and Hepatitis C Virus Patients in Korea

Jo HJ, Park GN, Kim HR, Kim MJ, Shin KA, Hong SB, Chang KS

Hepatitis B virus (HBV) and hepatitis C virus (HCV) chronically cause hepatitis, liver cirrhosis, and hepatocellular carcinoma, and biomarkers related to liver damage are elevated in HBV and HCV patients....
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Apolipoprotein E Polymorphism and Plasma Lipid Levels in Obese Children

Han MH, Kim SJ

  • KMID: 2207562
  • J Korean Pediatr Soc.
  • 2000 May;43(5):679-685.
PURPOSE: The increased prevalence of dyslipoproteinemia in obese children probably contributes to the high risk of cardiovascular disease associated with being overweight. The genetic makeup is possible one of the...
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Biological Predictors of Alzheimer's Disease Treatment

Joo SH, Im J, Lee CU

Variety of biomarkers that are related to the Alzheimer's disease and its diagnosis and progress have been found. However, research lacks in predicting the reaction of the treatment. In addition,...
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Apolipoprotein E Genotyping in the Diagnosis and Differential Diagnosis of Alzheimer's Disease

Bang OY, Kwak YT

  • KMID: 2065449
  • J Korean Neurol Assoc.
  • 2000 Sep;18(5):568-574.
BACKGROUND: There is a growing interest in the use of genetic markers in predicting the various types of dementia such as Alzheimer's disease (AD) and vascular dementia (VD). It is...
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Interaction of Apolipoprotein E epsilon4 and Education on Cognitive Decline in Korean Elders

Kim JM, Shin IS, Kim SW, Yang SJ, Park SW, Shin HY, Yoon JS

  • KMID: 1770033
  • Korean J Biol Psychiatry.
  • 2008 Feb;15(1):29-34.
OBJECTIVES: This study aimed to test potential modifying effects of education on the association between apolipoprotein E epsilon4 (Apo E4) and cognitive decline. METHODS: A community cohort(N=683) aged 65 or over...
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Apolipoprotein E Polymorphism in Korean Patients with Down's Syndrome

Han SH, Han MK, Lee DH, Kim JJ, Chung SY, Lee IK, Kim JQ

  • KMID: 2066000
  • J Korean Neurol Assoc.
  • 1995 Dec;13(4):767-772.
An association between the apolipoprotein E 4(APOE 4) allele and pathological changes in Alzheimer's disease(AD) is now well established. We analyzed the APOE genotype in patients with another amyloid forming...
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Comparison of Two Real-Time PCR Assays for Apolipoprotein E Genotyping

Jung YJ, Choi R, Chung JY, Lee MK, Ki CS, Kim JW

Apolipoprotein E (APOE) polymorphisms are used as biological markers to assess the risk of cardiovascular disease, dyslipidemia, and Alzheimer's disease. Consequently, APOE genotyping is one of the most frequently conducted...
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An Association Study of Apolipoprotein E Gene Polymorphism and Cataracts

Chi M, Im JS, Paik HJ

  • KMID: 2337936
  • J Korean Ophthalmol Soc.
  • 2011 Apr;52(4):420-428.
PURPOSE: To evaluate the association of apolipoprotein E (APOE) polymorphism and cataracts in the Korean population. METHODS: The present research included participants from a population-based study in Incheon, Korea. A sample...
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Apolipoprotein E Genotype and Expression Correlated with Hepatitis C Virus Genotype and Infection

Park GN, Jo HJ, Kim HR, Kim MJ, Shin KA, Hong SB, Chang KS

The hepatitis C virus (HCV) is a globally prevalent human pathogen that causes persistent liver infections in most infected individuals. Several studies reported that HCV particles are enriched in apolipoprotein...
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Apolipoprotein E Polymorphism in Patients with Myocardial Infarction

Jeong HS, Kim SK, Lee SC, Bang DW, Shin WY, On YK, Choe SC, Kim CH, Choi TM, Hyun MS, Jeon ES, Kwon YJ

BACKGROUND AND OBJECTIVES: In this study we investigated the association between the polymorphism of apolipoprotein E and the development of myocardial infarction, and assessed whether this polymorphism produces any changes...
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Analysis of Apolipoprotein E Genotypes in Several Demential diseases

Park YM, Jeon YM, Kwon GC, Koo SH, Park JW

  • KMID: 2225896
  • Korean J Clin Pathol.
  • 1999 Dec;19(6):642-646.
BACKGROUND: An increased frequency of the epsilon4 allele in Alzheimer's disease has been reported, which suggested a functional role of apolipoprotein E isoforms in pathophysiology of Alzheimer's disease. The aims...
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