- Antioxidant Effects of Sulfur-Containing Amino Acids
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Atmaca G
- KMID: 1103898
- Yonsei Med J.
- 2004 Oct;45(5):776-788.
- doi: 10.3349/ymj.2004.45.5.776
Sulfur is an essential element for the entire biological kingdom because of its incorporation into amino acids, proteins and other biomolecules. Sulfur atoms are also important in the iron-containing flavoenzymes.... -
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- The effects of pycnogenol on antioxidant enzymes in a mouse model of ozone exposure
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Lee MS, Moon KY, Bae DJ, Park MK, Jang AS
- KMID: 1501777
- Korean J Intern Med.
- 2013 Mar;28(2):216-223.
- doi: 10.3904/kjim.2013.28.2.216
BACKGROUND/AIMS: Ozone is an environmentally reactive oxidant, and pycnogenol is a mixture of flavonoid compounds extracted from pine tree bark that have antioxidant activity. We investigated the effects of pycnogenol... -
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- Exogenous rhTRX reduces lipid accumulation under LPS-induced inflammation
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Han GY, Lee EK, Park HW, Kim HJ, Kim CW
- KMID: 2155336
- Exp Mol Med.
- 2014 Jan;46(1):e71.
- doi: 10.1038/emm.2013.136
Redox-regulating molecule, recombinant human thioredoxin (rhTRX) which shows anti-inflammatory, and anti-oxidative effects against lipopolysaccharide (LPS)-stimulated inflammation and regulate protein expression levels. LPS-induced reactive oxygen intermediates (ROI) and NO production were... -
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- Neuroprotective effects of Vitis vinifera extract on prediabetic mice induced by a high-fat diet
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Jin HY, Cha YS, Baek HS, Park TS
- KMID: 1780106
- Korean J Intern Med.
- 2013 Sep;28(5):579-586.
- doi: 10.3904/kjim.2013.28.5.579
BACKGROUND/AIMS: Vitis vinifera grape seed extract (VVE) contains oligomeric proanthocyanidins that show antioxidant and free radical-scavenging activities. We evaluated VVE for its neuroprotective effect in prediabetic mice induce by a... -
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- Polyphenol (-)-Epigallocatechin Gallate during Ischemia Limits Infarct Size Via Mitochondrial K(ATP) Channel Activation in Isolated Rat Hearts
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Song DK, Jang Y, Kim JH, Chun KJ, Lee D, Xu Z
- KMID: 1778032
- J Korean Med Sci.
- 2010 Mar;25(3):380-386.
- doi: 10.3346/jkms.2010.25.3.380
Polyphenol (-)-epigallocatechin gallate (EGCG), the most abundant catechin of green tea, appears to attenuate myocardial ischemia/reperfusion injury. We investigated the involvement of ATP-sensitive potassium (K(ATP)) channels in EGCG-induced cardioprotection. Isolated... -
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- Effects of Combination Dietary Conjugated Linoleic Acid with Vitamin A (Retinol) and Selenium on the Response of the Immunoglobulin Production in Mice
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Kim JY, Chung BH
- KMID: 1099829
- J Vet Sci.
- 2003 Apr;4(1):103-108.
The dietary effect of conjugated linoleic acid (CLA) on the response of the immunoglobulin (serum and tissue) production in Balb/C mice was examined at three doses: 0 %(control), 0.5% and... -
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- Pyrrolidine Dithiocarbamate Inhibits Nuclear Factor kappaB and Toll-Like Receptor 4 Expression in Rats with Acute Necrotizing Pancreatitis
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Xu M, Wang KN, Wu K, Wang XP
- KMID: 2155650
- Gut Liver.
- 2015 May;9(3):411-416.
- doi: 10.5009/gnl14050
BACKGROUND/AIMS: To investigate the expression of Toll-like receptor 4 (TLR4) in the pancreases of rats with acute necrotizing pancreatitis (ANP) and any changes upon treatment with pyrrolidine dithiocarbamate (PDTC), an... -
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- AMP kinase/cyclooxygenase-2 pathway regulates proliferation and apoptosis of cancer cells treated with quercetin
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Lee YK, Park SY, Kim YM, Lee WS, Park OJ
- KMID: 1123467
- Exp Mol Med.
- 2009 Mar;41(3):201-207.
- doi: 10.3858/emm.2009.41.3.023
AMPK (AMP-activated protein kinase) is highly conserved in eukaryotes, where it functions primarily as a sensor of cellular energy status. Recent studies indicate that AMPK activation strongly suppresses cell proliferation... -
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- Melatonin reduces ultraviolet-B induced cell damages and polyamine levels in human skin fibroblasts in culture
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Lee KS, Lee WS, Suh SI, Kim SP, Lee SR, Ryoo YW, Kim BC
- KMID: 1109314
- Exp Mol Med.
- 2003 Aug;35(4):263-268.
UV radiation is known to cause photoaging of the skin and is considered one of the leading cause of developing skin carcinogenesis. Melatonin which has a highly lipophilic molecular structure... -
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- The Effects of Broccoli Sprout Extract Containing Sulforaphane on Lipid Peroxidation and Helicobacter pylori Infection in the Gastric Mucosa
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Chang YW, Jang JY, Kim YH, Kim JW, Shim JJ
- KMID: 2160632
- Gut Liver.
- 2015 Jul;9(4):486-493.
- doi: 10.5009/gnl14040
BACKGROUND/AIMS: The aims of this study were to investigate whether a broccoli sprout extract containing sulforaphane (BSES) inhibited the Helicobacter pylori infection density and exerted an antioxidative effect on gastric... -
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- Protective effects of silymarin on fumonisin B1-induced hepatotoxicity in mice
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Sozmen M, Devrim AK, Tunca R, Bayezit M, Dag S, Essiz D
- KMID: 1737610
- J Vet Sci.
- 2014 Mar;15(1):51-60.
- doi: 10.4142/jvs.2014.15.1.51
The present study was conducted to investigate the effect of silymarin on experimental liver toxication induced by Fumonisin B1 (FB1) in BALB/c mice. The mice were divided into six groups... -
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- An antioxidant modulates expression of receptor activator of NF-kappaB in asthma
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Lee KS, Park HS, Park SJ, Kim SR, Min KH, Jin SM, Li L, Lee YC
- KMID: 1094147
- Exp Mol Med.
- 2006 Jun;38(3):217-229.
Oxidative stress plays critical roles in airway inflammation that is usually accompanied by increased vascular permeability and plasma exudation. VEGF increases vascular permeability and leads to airway inflammation. In addition,... -
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- Free radical scavenging and antioxidant enzyme fortifying activities of extracts from Smilax china root
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Lee SE, Ju EM, Kim JH
- KMID: 1457540
- Exp Mol Med.
- 2001 Dec;33(4):263-268.
The extract from Smilax china root has been used as medicinal remedy and reported to retain antimicrobial and antimutagenic acitivities. In this study, a possible presence of antioxidant activity of... -
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- Protective Effects of Epigallocatechin Gallate After UV Irradiation of Cultured Human Lens Epithelial Cells
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Heo J, Lee BR, Koh JW
- KMID: 1070755
- Korean J Ophthalmol.
- 2008 Sep;22(3):183-186.
- doi: 10.3341/kjo.2008.22.3.183
PURPOSE: To evaluate the protective effects of epigallocatechin gallate (EGCG) against UV irradiation of cultured human lens epithelial cells. METHODS: We irradiated cultured human lens epithelial cells with... -
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- Sulforaphane Induces Antioxidative and Antiproliferative Responses by Generating Reactive Oxygen Species in Human Bronchial Epithelial BEAS-2B Cells
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Lee YJ, Lee SH
- KMID: 1123448
- J Korean Med Sci.
- 2011 Nov;26(11):1474-1482.
- doi: 10.3346/jkms.2011.26.11.1474
Sulforaphane (SFN) is a naturally occurring compound which is known to induce the phase II antioxidant genes via Nrf2 activation, although the underlying mechanism has not been fully elucidated. In... -
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- The effect of ferulic acid ethyl ester on leptin-induced proliferation and migration of aortic smooth muscle cells
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Tsai YC, Lee YM, Hsu CH, Leu SY, Chiang HY, Yen MH, Cheng PY
- KMID: 2155434
- Exp Mol Med.
- 2015 Aug;47(8):e180.
- doi: 10.1038/emm.2015.56
Leptin is a peptide hormone, which has a central role in the regulation of body weight; it also exerts many potentially atherogenic effects. Ferulic acid ethyl ester (FAEE) has been... -
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- Protective Effects of Epigallocatechin Gallate after UV Irradiation in Cultured Human Retinal Pigment Epithelial Cells
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Yang SW, Lee BR, Koh JW
- KMID: 754642
- Korean J Ophthalmol.
- 2007 Dec;21(4):232-237.
- doi: 10.3341/kjo.2007.21.4.232
PURPOSE: To evaluate the protective effects of Epigallocatechin gallate (EGCG) against UV irradiation in cultured human retinal pigment epithelial (RPE) cells. METHODS: UV irradiation was produced by a UV... -
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- Influence of ascorbic acid on BUN, creatinine, resistive index in canine renal ischemia-reperfusion injury
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Lee JI, Kim MJ, Park CS, Kim MC
- KMID: 1103559
- J Vet Sci.
- 2006 Mar;7(1):79-81.
- doi: 10.4142/jvs.2006.7.1.79
Renal ischemia as a course of renal transplantation is a common cause of renal dysfunction as renal failure. The purpose of this study was to investigate the influence of ascorbic... -
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- beta-Carotene inhibits inflammatory gene expression in lipopolysaccharide-stimulated macro phages by suppressing redox-based NF-kappaB activation
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Bai SK, Lee SJ, Na HJ, Ha KS, Han JA, Lee H, Kwon YG, Chung CK, Kim YM
- KMID: 1093467
- Exp Mol Med.
- 2005 Aug;37(4):323-334.
beta-Carotene has shown antioxidant and antiinflammatory activities; however, its molecular mechanism has not been clearly defined. We examined in vitro and in vivo regulatory function of beta-carotene on the production... -
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- Resveratrol inhibits foam cell formation via NADPH oxidase 1-mediated reactive oxygen species and monocyte chemotactic protein-1
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Park DW, Baek K, Kim JR, Lee JJ, Ryu SH, Chin BR, Baek SH
- KMID: 1123464
- Exp Mol Med.
- 2009 Mar;41(3):171-179.
- doi: 10.3858/emm.2009.41.3.020
Resveratrol is a polyphenolic compound in red wine that has anti-oxidant and cardioprotective effects in animal models. Reactive oxygen species (ROS) and monocyte chemotactic protein-1 (MCP-1) play key roles in... -
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