- Application of vincristine-loaded platelet therapy in three dogs with refractory immune-mediated thrombocytopenia
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Park HJ, Kim JW, Song KH, Seo KW
- KMID: 2160830
- J Vet Sci.
- 2015 Mar;16(1):127-130.
- doi: 10.4142/jvs.2015.16.1.127
Three dogs presented with refractory immune-mediated thrombocytopenia (IMT). All patients failed to respond to prednisone, which is considered a mainstay of immunosuppressive therapy. Vincristine-loaded platelets (VLPs), which act selectively on... -
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- Paclitaxel inhibits the hyper-activation of spleen cells by lipopolysaccharide and induces cell death
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Kim HJ, Joo HG
- KMID: 2412600
- J Vet Sci.
- 2016 Dec;17(4):453-458.
- doi: 10.4142/jvs.2016.17.4.453
Paclitaxel was isolated from the bark of the Pacific yew, Taxus brevifolia, and used as an anticancer agent. Paclitaxel prevents cancer cell division by inhibiting spindle fiber function, inducing cell... -
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- Orbital Metastatic Angiosarcoma
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Hassane S, Fouad E, Said I, Karim R, Asmae N, Houcine C, Abdelbar O
- KMID: 1769091
- Korean J Ophthalmol.
- 2010 Dec;24(6):364-366.
- doi: 10.3341/kjo.2010.24.6.364
We report a case of a 48-year-old man who developed metastatic angiosarcoma in her left orbit. A 48-year-old man was first sent to us for a check up of proptosis... -
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- Clinical Result of Prolonged Primary Chemotherapy in Retinoblastoma Patients
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Kim JH, Yu YS, Khwarg SI, Choi HS, Shin HY, Ahn HS
- KMID: 754340
- Korean J Ophthalmol.
- 2003 Jun;17(1):35-43.
- doi: 10.3341/kjo.2003.17.1.35
This study evaluated the effects of prolonged primary chemotherapy in retinoblastoma. The data for 27 eyes in 22 children who were treated for retinoblastoma with up to 13 cycles of... -
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- Nail Changes During Docetaxel Containing Combination Chemotherapy
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Woo IS, Shim KH, Kim GY, Lee MA, Kang JH, Hong YS, Lee KS
- KMID: 759702
- Korean J Intern Med.
- 2004 Jun;19(2):132-133.
Nail toxicity following systemic chemotherapy is common. Onychopathy during the period of neutropenia following chemotherapy may cause subungual abscesses and serious infection. Despite taxoid-related toxicity being increasingly reported since 2000,... -
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- Risk Factors for Febrile Neutropenia during Chemotherapy for HIV-Related Lymphoma
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Park J, Kim TM, Hwang JH, Kim NH, Choe PG, Song KH, Kim ES, Park SW, Kim HB, Kim NJ, Park WB, Oh MD
- KMID: 2157968
- J Korean Med Sci.
- 2012 Dec;27(12):1468-1471.
- doi: 10.3346/jkms.2012.27.12.1468
We evaluated risk factors for neutropenic fever and febrile prolonged neutropenia during vincristine-including chemotherapy to treat HIV-related lymphoma to investigate whether protease inhibitor (PI) treatment is associated with infectious complications... -
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- Antiproliferative effect of basic fibroblast growth factor-saporin mitotoxin on keratocytes in culture
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Wee WR, Parandoosh Z, Sakamoto T, Caton M, Nova M, McDonnell
- KMID: 1735150
- Korean J Ophthalmol.
- 1996 Jun;10(1):1-7.
- doi: 10.3341/kjo.1996.10.1.1
We evaluated the effect of the conjugate of basic fibroblast growth factor (FGF2) and saporin (FGF2-SAP) on proliferation of cultured keratocytes. Cultured rabbit and human keratocytes were incubated in medium... -
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- Tanshinone IIA, an ingredient of Salvia miltiorrhiza BUNGE, induces apoptosis in human leukemia cell lines through the activation of caspase-3
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Sung HJ, Choi SM, Yoon YS, An KS
- KMID: 1029923
- Exp Mol Med.
- 1999 Dec;31(4):174-178.
Tanshinone II-A is a derivative of phenanthrene-quinone isolated from Salvia miltiorrhiza BUNGE, a traditional herbal medicine that is known to induce antiinflammatory, anti-oxidative and cytotoxic activity. We have... -
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- Salinomycin reduces stemness and induces apoptosis on human ovarian cancer stem cell
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Lee HG, Shin SJ, Chung HW, Kwon SH, Cha SD, Lee JE, Cho CH
- KMID: 2413456
- J Gynecol Oncol.
- 2017 Mar;28(2):e14.
- doi: 10.3802/jgo.2017.28.e14
OBJECTIVE: Cancer stem cells (CSCs) represent a subpopulation of undifferentiated tumorigenic cells thought to be responsible for tumor initiation, maintenance, drug resistance, and metastasis. The role of CSCs in drug... -
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- Thermo-stability and antitumor activity on colon cancer cell lines of monoclonal anti-CEA antibody-saporin immunotoxin
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Manosroi J, Kleist SV, Manosroi A, Grunert F
- KMID: 1421902
- J Korean Med Sci.
- 1992 Jun;7(2):128-135.
- doi: 10.3346/jkms.1992.7.2.128
Eight saporin peaks were obtained from the purification of seed extracts of Saponaria officinalis L. Saporin peak No. 6 (SAP-6) showed the highest activity in the inhibition of protein... -
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- Individualized Tumor Response Testing for Prediction of Response to Paclitaxel and Cisplatin Chemotherapy in Patients with Advanced Gastric Cancer
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Kim JH, Lee KW, Kim YH, Lee KH, Oh DY, Kim J, Yang SH, Im SA, Choi SH, Bang YJ
- KMID: 1713950
- J Korean Med Sci.
- 2010 May;25(5):684-690.
- doi: 10.3346/jkms.2010.25.5.684
The purpose of our study was to determine the most accurate analytic method to define in vitro chemosensitivity, using clinical response as reference standard in prospective clinical trial, and to... -
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- Gossypol acetic acid induces apoptosis in RAW264.7 cells via a caspase-dependent mitochondrial signaling pathway
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Deng S, Yuan H, Yi J, Lu Y, Wei Q, Guo C, Wu J, Yuan L, He Z
- KMID: 1705558
- J Vet Sci.
- 2013 Sep;14(3):281-289.
- doi: 10.4142/jvs.2013.14.3.281
To investigate the effects of gossypol acetic acid (GA) on proliferation and apoptosis of the macrophage cell line RAW264.7 and further understand the possible underlying mechanism responsible for GA-induced cell... -
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- An open-label, multicenter, phase I trial of a cremophor-free, polymeric micelle formulation of paclitaxel combined with carboplatin as a first-line treatment for advanced ovarian cancer: a Korean Gynecologic Oncology Group study (KGOG-3016)
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Lee SW, Kim YM, Kim YT, Kang SB
- KMID: 2413442
- J Gynecol Oncol.
- 2017 May;28(3):e26.
- doi: 10.3802/jgo.2017.28.e26
OBJECTIVE: This phase I study aimed to determine the maximum tolerated dose (MTD) of Genexol-PM, when combined with carboplatin, as a first-line treatment in patients with advanced ovarian cancer. METHODS: This... -
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- Chlorophyll derivatives (CpD) extracted from silk worm excreta are specifically cytotoxic to tumor cells in vitro
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Lee WY, Park JH, Kim BS, Han MJ, Hahn BS
- KMID: 1107340
- Yonsei Med J.
- 1990 Sep;31(3):225-233.
- doi: 10.3349/ymj.1990.31.3.225
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- A Case of Cystoid Macular Edema Associated with Paclitaxel Chemotherapy
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Ham DS, Lee JE, Kim HW, Yun IH
- KMID: 1397491
- Korean J Ophthalmol.
- 2012 Oct;26(5):388-390.
- doi: 10.3341/kjo.2012.26.5.388
We encountered a patient with cystoid macular edema (CME) secondary to paclitaxel use. A 57-year-old man presented with gradual decreased bilateral vision. His chemotherapeutic regimen consisted of bevacizumab, paclitaxel (175... -
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- Efficacy of a Multiplex Paclitaxel Emission Stent Using a Pluronic® Mixture Membrane versus a Covered Metal Stent in Malignant Biliary Obstruction: A Prospective Randomized Comparative Study
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Jang SI, Lee SJ, Jeong S, Lee DH, Kim MH, Yoon HJ, Lee DK
- KMID: 2412238
- Gut Liver.
- 2017 Jul;11(4):567-573.
- doi: 10.5009/gnl16428
BACKGROUND/AIMS: A drug-eluting stent for unresectable malignant biliary obstruction was developed to increase stent patency by preventing tumor ingrowth. The safety and efficacy of a new generation of metallic stents... -
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- Safety and Efficacy of Overlapping Homogenous Drug-Eluting Stents in Patients with Acute Myocardial Infarction: Results from Korea Acute Myocardial Infarction Registry
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Ahmed K, Jeong MH, Chakraborty R, Hong YJ, Sim DS, Ahmed S, Hwang SH, Lee MG, Park KH, Kim JH, Ahn Y, Cho MC, Kim CJ, Kim YJ, Park JC, Kang JC, The Korea Acute Myocardial Infarction Registry Investigators
- KMID: 2157944
- J Korean Med Sci.
- 2012 Nov;27(11):1339-1346.
- doi: 10.3346/jkms.2012.27.11.1339
The aim of this study was to compare safety and efficacy of 4 homogenous overlapping drug-eluting stents (DES) in acute myocardial infarction (AMI) patients. We selected 1,349 consecutive patients (62.1... -
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- Blockade of VEGFR-1 and VEGFR-2 Enhances Paclitaxel Sensitivity in Gastric Cancer Cells
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Hwang JE, Lee JH, Park MR, Kim DE, Bae WK, Shim HJ, Cho SH, Chung IJ
- KMID: 1503899
- Yonsei Med J.
- 2013 Mar;54(2):374-380.
- doi: 10.3349/ymj.2013.54.2.374
PURPOSE: Hypoxia-inducible factor-1alpha (HIF-1alpha) increases transcription of the vascular endothelial growth factor (VEGF) gene. Inhibition of VEGF abolishes VEGF mediated induction of HIF-1alpha. Recent reports suggested that HIF-1alpha also mediated... -
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- Effect of petroleum ether extract of Panax ginseng roots on proliferation and cell cycle progression of human renal cell carcinoma cells
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Sohn J, Lee CH, Chung DJ, Park SH, Kim IS, Hwang WI
- KMID: 754987
- Exp Mol Med.
- 1998 Mar;30(1):47-51.
Panax ginseng roots have long been used as a medicinal herb in oriental countries. We have investigated anti-proliferative effects of lipid soluble Panax ginseng components on human renal cancer cell lines. Petroleum... -
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- Successful Treatment of Small-Cell Lung Cancer With Irinotecan in a Hemodialysis Patient With End-Stage Renal Disease
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Kim DM, Kim HL, Chung CH, Park CY
- KMID: 1785646
- Korean J Intern Med.
- 2009 Mar;24(1):73-75.
- doi: 10.3904/kjim.2009.24.1.73
The prognosis of patients with end-stage renal disease has improved with advances in hemodialysis techniques. However, many patients who undergo hemodialysis suffer from various types of cancer. Limited data is... -
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