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Ceftiaxone-Induced Neurotoxicity: Case Report, Pharmacokinetic Considerations, and Literature Review

Kim KB, Kim SM, Park W, Kim JS, Kwon SK, Kim HY

Ceftriaxone is widely used in patients for the treatment of serious gram-negative infections. Ceftriaxone can induce some potential side effects, including neurotoxicity, however, nonconvulsive status epilepticus has rarely been reported....
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Levofloxacin-Induced Achilles Tendinitis in a Young Adult in the Absence of Predisposing Conditions

Durey A, Baek YS, Park JS, Lee K, Ryu JS, Lee JS, Cheong MH

Fluoroquinolones (FQs) represent a major class of antimicrobials that have a high potential as therapeutic agents. Although FQs are generally safe for the use as antimicrobials, they may induce tendinopathic...
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Agranulocytosis Induced by Vancomycin in an ESRD Patient on CAPD

Jo YI, Yoon JH, Shin SY, Chang WC, Kim BK, Jin CJ, Song JO

  • KMID: 759687
  • Korean J Intern Med.
  • 2004 Mar;19(1):58-61.
Agranulocytosis is a rare adverse effect associated with prolonged vancomycin therapy, and is potentially serious, especially in end stage renal disease (ESRD) patients. We describe a continuous ambulatory peritoneal dialysis...
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Signal Detection of Imipenem Compared to Other Drugs from Korea Adverse Event Reporting System Database

Park K, Soukavong , Kim J, Kwon KE, Jin XM, Lee J, Yang BR, Park BJ

PURPOSE: To detect signals of adverse drug events after imipenem treatment using the Korea Institute of Drug Safety & Risk Management-Korea adverse event reporting system database (KIDS-KD). MATERIALS AND METHODS: We...
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Drug rash with eosinophilia and systemic symptoms syndrome following cholestatic hepatitis A: a case report

An J, Lee JH, Lee H, Yu E, Lee DB, Shim JH, Yoon S, Lee Y, Park S, Lee HC

Hepatitis A virus (HAV) infections occur predominantly in children, and are usually self-limiting. However, 75-95% of the infections in adults are symptomatic (mostly with jaundice), with the illness symptoms usually...
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Management of Antibiotics-Associated Diarrhea

Park HS, Han DS

Antibiotics-associated diarrhea (AAD) is defined as unexplained diarrhea that occurs with the administration of antibiotics. Approximately 20% AAD cases are due to Clostridium difficile. Over the last decade, the incidence...
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Minocycline-induced Periarticular Black Bones in Inflamed Joints Which Underwent Arthroplastic Reconstruction

Yang S, Takakubo Y, Kobayashi , Asano T, Sasaki A, Sasaki K, Ohki H, Tamaki Y, Takagi M

BACKGROUND: Minocycline-induced pigmentation of bone (black bone) is well described in tooth-bearing intra-oral bone, but is less known in periarticular bone in patients who have undergone total joint arthroplasty. On...
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Antibiotics-associated Diarrhea and Other Gastrointestinal Abnormal Responses Regarding Helicobacter pylori Eradication

Kwon SB, Lee KL, Kim JS, Lee JK, Kim W, Jung YJ, Jeong JB, Kim JW, Kim BG

BACKGROUND/AIMS: Helicobacter pylori (H. pylori) is closely related with a wide range of gastrointestinal disease. One-week triple therapy is currently considered as the golden standard for the treatment of H....
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Effect of Probiotic Lactobacillus (Lacidofil(R) Cap) for the Prevention of Antibiotic-associated Diarrhea: A Prospective, Randomized, Double-blind, Multicenter Study

Song HJ, Kim JY, Jung SA, Kim SE, Park HS, Jeong Y, Hong SP, Cheon JH, Kim WH, Kim HJ, Ye BD, Yang SK, Kim SW, Shin SJ, Kim HS, Sung JK, Kim EY

Antibiotic-associated diarrhea (AAD) is a common complication of antibiotic use. There is growing interest in probiotics for the treatment of AAD and Clostridium difficile infection because of the wide availability...
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