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The Effects of Amrinone and Milrinone on Myocardium in the Isolated Isoflurane-Exposed Rat Heart

Kim SW, Lee MK, Yoon SM

BACKGROUND: The aims of this study were to test if amrinone or milrinone reverses cardiac depression induced by the exposure to isoflurane in the isolated heart and to determine whether...
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Comparison of Hemodynamic Effects between Dobutamine and Amrinone in the Patients with Pulmonary Hypertension

Hong YW, Kwak YL, Min SK, Nam SB, Bang SO, Yoo ES, Kim MO, Kim MS

BACKGROUND: Dobutamine and amrinone, phosphodiesterase-III inhibitor, are known to have both inotropic and vasodilatory properties. We evaluated the effects of both drugs on systemic and pulmonary hemodynamics in patients with...
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Effects of Amrinone on Systemic and Pulmonary Arterial Pressure in Infants with Intracardiac Left to Right Shunt

Um SY, Chung CJ, Chin YJ

BACKGROUND: Amrinone is a nonglycosidic noncatecholamine with both vasodilator and positive inotropic effects that has not been evaluated widely in pediatric patients with intracardiac left to right shunts. The present...
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Effects of Amrinone on the Systemic and Pulmonary Hemodynamics in Patients with Pulmonary Hypertension

Kwak YL, Yoo ES, Lim HK, Lee CS, Hong YW, Bang SO, Han SY

BACKGROUND: Amrinone is a noncatecholamine, nonglycoside agent with both inotropic and vasodilatory properties and therefore seems suitable for therapy of right ventricular(RV) dysfunction. The effects of amrinone on systemic and...
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Effect of Amrinone, a Selective Inhibitor of Phosphodiesterase III, on PMNs-induced Cardiac Dysfunction in Ischemia/reperfusion

Oh BK, Kim HK, Choi SR, Song JH, Park ES, Choi BS, Park JD, Shin YK

  • KMID: 1517036
  • Korean J Physiol Pharmacol.
  • 2004 Feb;8(1):43-50.
Ischemia followed by reperfusion in the presence of polymorphonuclear leukocytes (PMNs) results in a marked cardiac contractile dysfunction. Amrinone, a specific inhibitor of phosphodiesterase 3, has an antioxidant activity against...
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Effects of Amrinone on the Vascular Tension of the Isolated Rabbit Pulmonary Artery

Cho SY, Suh JK, Shin WJ, Yeom JH, Oh MK, Kim KH, Yoo HK

BACKGROUND: Amrinone is a noncatecholamine, nonglycoside compound, which is known to possess both cardiac inotropic and vasodilatory actions. This drugs has been increasingly used in clinical practice for the management...
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Effects of Amrinone and Dobutamine on Regional Myocardial Function and Oxygen Balance in Normal and Stunned Myocardium in Dogs

Park JS, Park JE, Jeong ST, Jeong S, Chung SS, Yoo KY

  • KMID: 1590021
  • Korean J Crit Care Med.
  • 2005 Jun;20(1):14-23.
BACKGROUND: We examined the effects of amrinone and dobutamine on regional mechanical function, coronary blood flow (CBF), and myocardial oxygen consumption (MVO2) in normal and stunned myocardium in an open-chest...
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Effects of Amrinone on Regional Myocardial Function and Oxygen Balance in Stunned Myocardium in Dogs

Yoo KY, Kim JS, Jeong ST, Jeong SW, Park JE, Im WM, Ha IH

BACKGROUND: Brief myocardial ischaemia has been demonstrated to result in mechanical and coronary endothelial dysfunction. We examined whether the mechanical and vascular responses to amrinone are altered in...
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Attenuating Effect of cAMP on Hypoxic Pulmonary Vasoconstriction in the Isolated Perfused Rat Lungs

Rhee KY, Kim JH, Ro YJ, Park CD, Min SW, Kim SD, Kim YL

BACKGROUND: Pulmonary vessels constrict when they are exposed to hypoxia, unlike other vessels. It is hypothesized that the decreased concentration of cAMP in the hypoxic condition causes this reaction, HPV...
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Comparison of Amrinone and Dopamine-Nitroglycerin on Hemodynamic Parameters in Dogs with Postinfarct Heart Failure

Kim SJ, Oh JH, Park JW, Jung YH, Oh HJ, Oh SW, Woo YC, Kim JY, Koo GH, Park SG

BACKGROUND: Left ventricular failure (LVF) after an acute myocardial infarction occurs during the perioperative period, and since this condition can lead to severe complications, intensive care is required for...
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Effects of Clonidine on the Requirements of Dopamine Used as a Concomitant Drug of Amrinone in Coronary Artery Bypass Surgery (CABG)

Kim HB, Park SY, Kim TY

BACKGROUND: Clonidine premedication has many beneficial effects in patients undergoing CABG surgery. Amrinone, having the ability to increase cardiac performance without increasing myocardial O2 consumption, is a valuable drug...
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Anesthetic Management of Ovarian Bleeding with Eisenmenger's Syndrome: A case report

Kim HB, Park SY, Kim TY, Kim IK, Shin MK, Yoon HW

Eisenmenger's syndrome is defined as a high pulmonary vascular resistance associated with pulmonary hypertension or high pulmonary pressure close to systemic values with a reverse or bidirectional shunt at aortopulmonary,...
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A Ratio of Arterial Oxygen Tension to Inspired Oxygen Fraction (PaO2/FiO2 ratio) after Cardiopulmonary Bypass in Coronary Artery Bypass Graft Surgery: Amrinone-Dopamine versus Isosorbide Dinitrate-Dopamine

Kim TY, Lim BW, Park TS, Lee SH, Kim IK, Shin MK

BACKGROUND: Cardiopulmonary bypass (CPB) may produce lung injury with decreased PaO2/FiO2 ratio in patients undergoing CABG surgery. We examined PaO2/FiO2 ratio and incidence of PaO2/FiO2 < 300 or 150 to...
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Hemodynamic Responses and Changes in Oxygen Extraction When Using Amrinone, Dobutamine and Isoproterenol in Cardiac Tamponade-Induced Dogs

Chung SW, Kim JM, Cheun JK, Kim AR, An YJ

BACKGROUND: Cardiac tamponade is most commonly treated by needle aspiration or surgical drainage. During this process, it may be necessary to temporarily improve cardiac output and to maintain peripheral...
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A Case of Sustained-release Verapamil Intoxication due to Overdose

Kang CD, Kim SW, Kim EJ, Lee EM, Park CK, Seo HS, Kwon YJ, Pyo HJ, Oh DJ

  • KMID: 1999032
  • J Korean Soc Emerg Med.
  • 1998 Mar;9(1):169-176.
Verapamil overdose results in cardiac arrhythmia including the complete A-V block, and hypotension due to decreased peripheral resistance and decreased myocardial contractility. However, sustained-release verapamil overdose frequently has atypical presentations,...
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Effects of Inotropic Drugs on Mechanical Function and Oxygen Balance in Postischemic Canine Myocardium: Comparison of Dobutamine, Epinephrine, Amrinone, and Calcium Chloride

Yoo KY, Kim H, Jeong CW, Park HC, Bae HB, Lee JU

Brief ischemic episodes that induce myocardial and coronary endothelial dysfunction may alter the responses to inotropic drugs. To determine the effects of inotropic drugs in stunned myocardium, the coronary blood...
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The Comparison of Anesthetic Agents and Adjuvants between University Hospitals, General Hospitals and Hospitals

Woo JK, Chung YJ

BACKGROUND: This study was performed to compare anesthetic agents and adjuvants for general anesthesia or regional anesthesia between university hospitals, resident-training general hospitals and hospitals without training program of residents. METHODS:...
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