- Genetic Analyses of the Chimeric CYP11B1/CYP11B2 Gene in a Korean Family with Glucocorticoid-Remediable Aldosteronism
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Lee IS, Kim SY, Jang HW, Kim MK, Lee JH, Lee YH, Jo YS
- KMID: 1785922
- J Korean Med Sci.
- 2010 Sep;25(9):1379-1383.
- doi: 10.3346/jkms.2010.25.9.1379
Glucocorticoid-remediable aldosteronism (GRA) is an autosomal-dominant inheritable form of hyperaldosteronism with early onset hypertension. GRA is caused by unequal crossing-over of the steroid 11beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) genes.... -
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- Renin-Angiotensin-Aldosterone System (RAAS) Gene Polymorphism as a Risk Factor of Coronary In-Stent Restenosis
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Ryu SK, Cho EY, Park HY, Im EK, Jang Y, Shin GJ, Shim WH, Cho SY
- KMID: 1122005
- Yonsei Med J.
- 2002 Aug;43(4):461-472.
- doi: 10.3349/ymj.2002.43.4.461
Intimal proliferation is a main cause of in-stent restenosis. Over-excretion of angiotensin I converting enzyme (ACE) and aldosterone is reported to stimulate intimal hyperplasia and the genetic effect of these... -
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