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Three Cases of Reversible Agranulocytosis after Treatment with Lamotrigine

Ahn YM, Kim K, Kim YS

Several psychotropic drugs, including clozapine, are known to cause agranulocytosis and this may lead to a fatal condition. Lamotrigine is an anticonvulsant that the Food and Drug Administration (FDA) has...
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A case of agranulocytosis following psychotropic agent therapy

Hong KW

  • KMID: 1692490
  • J Korean Neuropsychiatr Assoc.
  • 1993 Jul;32(4):589-593.
No abstract available.
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Granulocyte-Colony Stimulating Factor(G-CSF) Treatment of Clozapine-induced Agranulocytosis

Kim C, Shin S

  • KMID: 2286975
  • Korean J Psychopharmacol.
  • 1998 Apr;9(1):91-97.
After 31 weeks of treatment with clozapine, severe agranulocytosis was diagnosed in a 35-year-old male schizophrenic patient. The patient was treated sucessfully with a granulocyte colony-stimulating factor (G-CSF). The leukocyte...
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A Cases of Q Fever with Agranulocytosis

  • KMID: 1661926
  • J Korean Pediatr Soc.
  • 1995 Jun;38(6):848-852.
No abstract available.
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A case of Methimazole-Induced Cholestatic Jaundice With Agranulocytosis

Kang SG, Bae JO, Lee EY, Lim SM, Cho SK, Kim JH, Song SK

Methimazole is a widely used and generally well-tolerated antithyroid agent. Adverse reactions occur in 1~5% of patients taking methimazole medication, but these are most commonly transient, benign leukopenia and a...
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A Case of Antithyroid Drug-Induced Agranulocytosis Treated with Granulocyte Colony-Stimulating Factor (G-CSF) and Methylprednisolone

Eom TH, Jeoun HJ, Cho SM, Jung MH, Suh BK, Lee BC

  • KMID: 1568605
  • J Korean Soc Pediatr Endocrinol.
  • 2004 Jun;9(1):81-85.
Although rare, agranulocytosis is the most serious, potentially fatal side effect of antithyroid drug. We experienced a 13-year-old girl who developed methimazole-induced agranulocytosis at 1 month after the initiation of...
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A case of propylthiouracil-induced hepatitis with agranulocytosis

Lee JK, Kim HJ, Oh HE

  • KMID: 2143076
  • Korean J Med.
  • 2001 Jul;61(1):50-52.
Hyperthyroidism is a common condition which is initially managed with an antithyroid drug, either propylthiouracil or methimazole. Adverse reactions occur in 1-5% of patients taking antithyroid medications, most commonly transient,...
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Agranulocytosis due to secondary exposure to antithyroid drugs in a relapsed Graves' disease patient

Jeong GH, Kim SK, Myung DS, Chung JO, Cho DH, Chung DJ, Chung MY

  • KMID: 2258791
  • Korean J Med.
  • 2008 Sep;75(3):362-366.
Antithyroid drugs are the most common treatment modality for Graves' disease and are used for the treatment of relapsed Graves' disease in Korea. Agranulocytosis is a rare and severe complication...
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Late Onset Agranulocytosis with Clozapine Associated with HLA DR4 Responding to Treatment with Granulocyte Colony-stimulating Factor: A Case Report and Review of Literature

Singh A, Grover S, Malhotra P, Varma SC

Agranulocytosis as a side effect of clozapine has been reported to be associated with initial phases of treatment, i.e., first six months. Agranulocytosis with clozapine during the initial phases of...
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Allopurinol-induced agranulocytosis in a patient on peritoneal dialysis

Kim JK, Lee YK, Noh JW, Ahn BM, Kim JH, Jung YO, Park MJ

  • KMID: 1490333
  • Korean J Med.
  • 2009 Mar;76(3):365-369.
Agranulocytosis is a rare, but sometimes dangerous, adverse reaction to allopurinol. We report the unusual case of a 43-year-old man with agranulocytosis, who received allopurinol while undergoing peritoneal dialysis. The...
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A Case of Methimazole-induced Agranulocytosis and Kikuchi's Disease in a Patient with Graves' Disease

Lee SE, Ahn J, Kim J, Oh YS, Chung YJ

Methimazole-induced agranulocytosis is a rare, but critical side effect that should be recognized as soon as possible since it may induce a life-threatening condition when it was overlooked. Histiocytic necrotizing...
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A Cabe of Clozapine-Induced Agranulocytosis

Lee GC, Jung HK, Lee JH, Choi YM, Jeon SI, Choi SJ

  • KMID: 2017707
  • J Korean Neuropsychiatr Assoc.
  • 1998 Jan;37(1):186-193.
We report a 20-year-old female patient who developed clozapine-induced agranulocytosis on the 29th day of clozapine treatment. She recovered from the agranulocytosis on the 8th day of progression after treatment...
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Levamisole-Induced Reversible Agranulocytosis in Children with Steroid Dependent Nephrotic Syndrome

Lee SJ, Hwang SJ, Yoo ES, Lee SJ

  • KMID: 2142401
  • J Korean Pediatr Soc.
  • 1999 Apr;42(4):576-579.
Levamisole has been used for nephrotic syndrome due to its immunostimulating, immunomodulating, and steroid-sparing effects. Agranulocytosis, a serious side effect of levamisole, was rare and mostly associated with autoimmune disease,...
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Agranulocytosis and Neutropenia in Clozapine-Treated Patients

Cho HS, An SK, Kim CH, Lee HS

  • KMID: 1554203
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):166-172.
OBJECTIVE: Clozapine is effective in the treatment of refractory schizophrenic patients, but can cause reversible and fatal food dyscrasias. This study documents the incidence of agranulocytosis and neutropenia and the...
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Combined Antitumor Chemotherapy in a Refractory Schizophrenic Receiving Clozapine

Lee SY, Cheon YH, Rho SH, Lee KH, Park MC

  • KMID: 2340430
  • J Korean Neuropsychiatr Assoc.
  • 2000 Jan;39(1):234-239.
It has been known that clozapine treatment combining with cytotoxic antitumor therapy for schizophrenia is not recommended because both durgs have agranulocytosis as their side effect. Since the introduction of...
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The effect of granulocyte colony stimulating facto(G-CSF) in a patient with propylthiouracil-induced agranulocytosis

You KH, Son SS, Song SY, Park MS, Lee YG, Cho CG

  • KMID: 1686883
  • J Korean Soc Endocrinol.
  • 1993 Sep;8(3):347-350.
No abstract available.
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A Case of Agranulocytosis and Soft Tissue Abscess after Increasing Methimazole Dose in a Patient with Graves Disease under Long-term Mainternance Therapy

Park SY, Chun SW, Kim YJ, Kim SJ

  • KMID: 2012972
  • J Korean Thyroid Assoc.
  • 2011 May;4(1):54-57.
Antithyroid drugs (ATD) has been widely used to treat Graves' disease. However agranulocytosis, a serious fatal complication of ATD treatment, occurs in about 0.5 percent. The symptoms may mimic viral...
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Clozapine-induced Agranulocytosis

Lee HS, Kim JH, Lee HS, Do JH, Kim CH, Yoo KJ

  • KMID: 2340034
  • J Korean Neuropsychiatr Assoc.
  • 1997 Jan;36(1):204-208.
The authors reported one case of agranulocytosis that occurred in the clozapine treatment in a 34-year-old male patient with chronic schizophrenia. Agranulocytosis, a WBC count of 2700 with 4% neutrophils,...
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A Case of Agranulocytosis Induced by Risperidone and Treated with Granulocyte-Colony Stimulating Factor

Kim W, Kim JJ, Woo YS, Jun TY, Bahk WM

  • KMID: 2286797
  • Korean J Psychopharmacol.
  • 2005 Nov;16(6):529-533.
Agranulocytosis is a severe hematologic complications of clozapine, but risperidone was not shown to induce agranulocytois. Nevertheless, some cases of risperidone-induced agranulocytosis were being reported, but there was no report...
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Agranulocytosis Induced by Vancomycin in an ESRD Patient on CAPD

Jo YI, Yoon JH, Shin SY, Chang WC, Kim BK, Jin CJ, Song JO

  • KMID: 759687
  • Korean J Intern Med.
  • 2004 Mar;19(1):58-61.
Agranulocytosis is a rare adverse effect associated with prolonged vancomycin therapy, and is potentially serious, especially in end stage renal disease (ESRD) patients. We describe a continuous ambulatory peritoneal dialysis...
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