- Role of Reactive Oxygen Species in the Adipogenesis of Adipose-derived Stem Cells
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Chang H, Min KH, Park YI, Kim YH, Minn KW
- KMID: 2322173
- J Korean Soc Plast Reconstr Surg.
- 2011 Mar;38(2):131-134.
PURPOSE: Stem cells continue to receive research attention in the clinical fields, and adipose-derived stem cells(ADSCs) have been shown to be a good source raw material. Many plastic surgeons are... -
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- The Regulatory Effects of Trans-chalcone on Adipogenesis
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Han Y
- KMID: 2437482
- Int J Oral Biol.
- 2018 Mar;43(1):29-35.
- doi: 10.11620/IJOB.2018.43.1.029
It is noted that chalcone derivatives have characteristic diverse pharmacological properties, and that precise evidence has been growing that they could regulate a tumor necrosis factor-α (TNF-α) induced insulin resistance.... -
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- Regulation of Adipocyte Differentiation via MicroRNAs
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Son YH, Ka S, Kim AY, Kim JB
- KMID: 2169416
- Endocrinol Metab.
- 2014 Jun;29(2):122-135.
- doi: 10.3803/EnM.2014.29.2.122
Adipocyte differentiation, termed adipogenesis, is a complicated process in which pluripotent mesenchymal stem cells differentiate into mature adipocytes. The process of adipocyte differentiation is tightly regulated by a number of... -
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- Capsanthin Inhibits both Adipogenesis in 3T3-L1 Preadipocytes and Weight Gain in High-Fat Diet-Induced Obese Mice
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Jo SJ, Kim JW, Choi HO, Kim JH, Kim HJ, Woo SH, Han BH
- KMID: 2378812
- Biomol Ther.
- 2017 May;25(3):329-336.
- doi: 10.4062/biomolther.2017.048
Adipogenesis in murine preadipocyte 3T3L-1 has been used as a model system to study anti-obese bioactive molecules. During adipogenesis in 3T3-L1 preadipocytes, we found that capsanthin inhibited adipogenesis (ICâ‚…â‚€; 2.5... -
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- Inhibitory Effects of Corni Fructus Extract on Angiogenesis and Adipogenesis
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Hwang JH, Kim JD
- KMID: 2389108
- Korean J Physiol Pharmacol.
- 2011 Feb;15(1):43-51.
Natural products in Chonnam, Korea were screened via anti-angiogenesis experiments, and 1 candidate product was identified, Corni fructus, which exerted dose-dependent inhibitory effects against angiogenesis, adipogenesis, and cell adhesion. C.... -
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- Duration and Magnitude of Extracellular Signal-Regulated Protein Kinase Phosphorylation Determine Adipogenesis or Osteogenesis in Human Bone Marrow-Derived Stem Cells
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Jung HS, Kim YH, Lee JW
- KMID: 1106452
- Yonsei Med J.
- 2011 Jan;52(1):165-172.
- doi: 10.3349/ymj.2011.52.1.165
PURPOSE: Imbalances between osteogenic and adipogenic differentiation leads to diseases such as osteoporosis. The aim of our study was to demonstrate the differences in extracellular signal-regulated kinase (ERK) phosphorylation during... -
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- Role of protease inhibitors and acylation stimulating protein in the adipogenesis in 3T3-L1 cells
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Soliman MM, El-Senosi , Salem MM, Hamid OM, Kazuhiro K
- KMID: 1726918
- J Vet Sci.
- 2009 Sep;10(3):197-201.
- doi: 10.4142/jvs.2009.10.3.197
Treatment of AIDS (HIV) and hepatitis C virus needs protease inhibitors (PI) to prevent viral replication. Uses of PI in therapy are usually associated with a decrease in body weight... -
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- Tributyltin increases the expression of apoptosis- and adipogenesis-related genes in rat ovaries
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Lee H, Lim S, Yun S, Yoon A, Park G, Yang H
- KMID: 2167515
- Clin Exp Reprod Med.
- 2012 Mar;39(1):15-21.
- doi: 10.5653/cerm.2012.39.1.15
OBJECTIVE: Tributyltin (TBT), an endocrine disrupting chemical, has been reported to decrease ovarian function by causing apoptosis in the ovary, but the mechanism is not fully understood. Therefore, we examined... -
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- The micosporine-like amino acids-rich aqueous methanol extract of laver (Porphyra yezoensis) inhibits adipogenesis and induces apoptosis in 3T3-L1 adipocytes
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Kim H, Lee Y, Han T, Choi EM
- KMID: 2313882
- Nutr Res Pract.
- 2015 Dec;9(6):592-598.
- doi: 10.4162/nrp.2015.9.6.592
BACKGROUND/OBJECTIVES: Increased mass of adipose tissue in obese persons is caused by excessive adipogenesis, which is elaborately controlled by an array of transcription factors. Inhibition of adipogenesis by diverse plant-derived... -
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- The Mechanism of White and Brown Adipocyte Differentiation
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Nakagami H
- KMID: 2280709
- Diabetes Metab J.
- 2013 Apr;37(2):85-90.
- doi: 10.4093/dmj.2013.37.2.85
Obesity gives vent to many diseases such as type 2 diabetes, hypertension, and hyperlipidemia, being considered as the main causes of mortality and morbidity worldwide. The pathogenesis and pathophysiology of... -
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- The Inhibitory Effect of Testosterone on PPARγ-induced Adipogenesis
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Jeong S
- KMID: 2328214
- Korean J Obes.
- 2016 Jun;25(2):68-76.
- doi: 10.7570/kjo.2016.25.2.68
BACKGROUND: Peroxisome proliferator-activated receptor γ (PPARγ) plays a major role in adipocyte differentiation. Testosterone is well known for inhibiting adipocyte metabolism in men. To investigate the inhibitory mechanism of testosterone... -
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- A Cannabinoid Receptor Agonist N-Arachidonoyl Dopamine Inhibits Adipocyte Differentiation in Human Mesenchymal Stem Cells
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Ahn S, Yi S, Seo WJ, Lee MJ, Song YK, Baek SY, Yu J, Hong SH, Lee J, Shin DW, Jeong LS, Noh M
- KMID: 2380330
- Biomol Ther.
- 2015 May;23(3):218-224.
- doi: 10.4062/biomolther.2014.137
Endocannabinoids can affect multiple cellular targets, such as cannabinoid (CB) receptors, transient receptor potential cation channel, subfamily V, member 1 (TRPV1) and peroxisome proliferator-activated receptor gamma (PPARgamma). The stimuli to... -
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- Anti-obesity effect of EGCG and glucosamine-6-phosphate through decreased expression of genes related to adipogenesis and cell cycle arrest in 3T3-L1 adipocytes
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Kim KB, Jang SH
- KMID: 2327454
- J Nutr Health.
- 2014 Feb;47(1):1-11.
PURPOSE: Several studies have proven that EGCG, the primary green tea catechin, and glucosamine-6-phosphate (PGlc) reduce triglyceride contents in 3T3-L1 adipocytes. The objective of this study is to evaluate the... -
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- Anti-adipogenic effect of mulberry leaf ethanol extract in 3T3-L1 adipocytes
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Yang SJ, Park NY, Lim Y
- KMID: 2313786
- Nutr Res Pract.
- 2014 Dec;8(6):613-617.
- doi: 10.4162/nrp.2014.8.6.613
BACKGROUND/OBJECTIVES: Adipogenesis is part of the cell differentiation process in which undifferentiated fibroblasts (pre-adipocytes) become mature adipocytes with the accumulation of lipid droplets and subsequent cell morphological changes. Several transcription... -
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- The Effects of Epigallocatechin on Adipogenesis of 3T3-L1 Preadipocytes
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Park SG, Kim JS, Kim NG, Park TG, Kim JY
- KMID: 2119896
- J Korean Soc Plast Reconstr Surg.
- 2004 Jan;31(1):83-88.
Preadipocyte cell lines are useful models for investigating adipogenesis process. 3T3-L1 preadipocyte, which can be induced to differentiate into adipocyte in cell culture, is one of the most studied preadipocyte... -
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- Low-Frequency Intermittent Hypoxia Suppresses Subcutaneous Adipogenesis and Induces Macrophage Polarization in Lean Mice
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Wang Y, Lee MY, Mak JC, Ip MS
- KMID: 2460959
- Diabetes Metab J.
- 2019 Oct;43(5):659-674.
- doi: 10.4093/dmj.2018.0196
BACKGROUND: The relationship between obstructive sleep apnoea (OSA) and metabolic disorders is complex and highly associated. The impairment of adipogenic capacity in pre-adipocytes may promote adipocyte hypertrophy and increase the... -
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- The N- and C-terminal domains of parathyroid hormone-related protein affect differently the osteogenic and adipogenic potential of human mesenchymal stem cells
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Casado-Diaz A, Santiago-Mora R, Quesada JM
- KMID: 983981
- Exp Mol Med.
- 2010 Feb;42(2):87-98.
- doi: 10.3858/emm.2010.42.2.010
Parathyroid hormone-related protein (PTHrP) is synthesized by diverse tissues, and its processing produces several fragments, each with apparently distinct autocrine and paracrine bioactivities. In bone, PTHrP appears to modulate bone... -
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- Arctiin inhibits adipogenesis in 3T3-L1 cells and decreases adiposity and body weight in mice fed a high-fat diet
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Min B, Lee H, Song JH, Han MJ, Chung J
- KMID: 2313792
- Nutr Res Pract.
- 2014 Dec;8(6):655-661.
- doi: 10.4162/nrp.2014.8.6.655
BACKGROUND/OBJECTIVES: The purpose of this study was to examine the effects and associated mechanisms of arctiin, a lignan compound found in burdock, on adipogenesis in 3T3-L1 cells. Also, the effects... -
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- Pear pomace water extract inhibits adipogenesis and induces apoptosis in 3T3-L1 adipocytes
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Rhyu J, Kim MS, You MK, Bang MA, Kim HA
- KMID: 2313708
- Nutr Res Pract.
- 2014 Feb;8(1):33-39.
Obesity occurs when a person's calorie intake exceeds the amount of energy burns, which may lead to pathologic growth of adipocytes and the accumulation of fat in the tissues. In... -
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- Adipogenic and Lipolytic Effects of Ascorbic Acid in Ovariectomized Rats
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Kim B, Choi KM, Yim HS, Park HT, Yim JH, Lee MG
- KMID: 2418853
- Yonsei Med J.
- 2018 Jan;59(1):85-91.
- doi: 10.3349/ymj.2018.59.1.85
PURPOSE: Ascorbic acid has been reported to have an adipogenic effect on 3T3-L1 preadipocytes, while evidence also suggests that ascorbic acid reduces body weight in humans. In this study, we... -
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