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Effects of aluminum on choline uptake and activities of choline acetyltransferase and acetylcholinesterase in rat brain

Woo JI, Yeon BK, Suh YH, Park CW, Lee CK

  • KMID: 1692027
  • J Korean Neuropsychiatr Assoc.
  • 1991 Nov;30(6):961-973.
No abstract available.
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Production of the Acetylcholinesterase Inhibitor from Yarrowia lipolytica S-3

Lee DH, Lee JS, Yi SH, Lee JS

  • KMID: 2411404
  • Mycobiology.
  • 2008 Jun;36(2):102-105.
The acetylcholinesterase (AChE) inhibitor of Yarrowia lipolytica S-3 was maximally produced when it was incubated at 30degrees C for 36 h in an optimal medium containing 1% yeast extract, 2%...
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Biological Predictors of Alzheimer's Disease Treatment

Joo SH, Im J, Lee CU

Variety of biomarkers that are related to the Alzheimer's disease and its diagnosis and progress have been found. However, research lacks in predicting the reaction of the treatment. In addition,...
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Acetylcholinesterase Inhibitors from Angelica polymorpha Stem

Kwon Y, Kim HP, Kim MJ, Chun W

Fourteen compounds were isolated from the stem of Angelica polymorpha. On the basis of spectral data, these compounds were identified as isoimperatorin (1), phellopterin (2), bergapten (3), xanthyletin (4), cnidilin...
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A new 3, 4-epoxyfurocoumarin from Heracleum moellendorffii Roots

Park SY, Lee N, Lee S, Kim MJ, Chun W, Kim HP, Yang HJ, Lee HS, Kwon Y

Activity-guided isolation of Heracleum moellendorffii roots led to four coumarin derivatives as acetylcholinesterase inhibitors. The structures of these isolates were characterized by spectroscopic method to be angelicin (1), isobergapten (2),...
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Dysarthria after Donepezil

Jung S, Baik JS

  • KMID: 2186035
  • J Korean Neurol Assoc.
  • 2001 Mar;19(2):170-172.
We report a case of speech disturbance as an unrecognized adverse effect of the selective acetylcholinesterase inhibitor, donepezil. A 79-year-old woman presented with progressive memory disturbance that began 3 years...
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Isolation, Identification and Characterization of a Antidementia Acetylcholinesterase Inhibitor-Producing Yarrowia lipolytica S-3

Kang MG, Yoon MH, Choi YJ, Lee JS

  • KMID: 2408211
  • Mycobiology.
  • 2012 Mar;40(1):42-46.
This report describes the isolation and identification of a potent acetylcholinesterase (AChE) inhibitor-producing yeasts. Of 731 species of yeast strain, the S-3 strain was selected as a potent producer of...
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A Case of Positive Amniotic AFP, Acetylcholinesterase in a Normal Pregnancy after Undergoing Periodic Targeted Ultrasonographic Evaluation

Ri PH, Sun JH, Cha DH, Park SW, Chung CJ

  • KMID: 2072166
  • Korean J Perinatol.
  • 2006 Dec;17(4):413-418.
Neural tube defects are reported one of the important congenital malformation in the world, with an incidence of 1.4 to 2 per 1000 pregnancies. Maternal serum AFP at the second...
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Effect of Soy Isoflavone Intake on Water Maze Performance and Brain Acetylcholinesterase Activity in Rats

Oh HK, Kim SH

  • KMID: 2269955
  • Korean J Nutr.
  • 2006 Apr;39(3):219-224.
This study was performed to determine the effect of soy isoflavones on brain development and function in rats. Forty Sprague-Dawley male rats were provided diets containing different levels of soy...
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The nervous system of Fibricola seoulensis by acetylcholinesterase histochemistry

Cheon EW, Kim CH

F. seoulensis were obtained from artificially infected albino rats at 3, 4, 5, 6, 7 days after infection. The worms and metacercariae were washed in physiological saline solution, and fixed...
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Nutritional and Physicochemical Characteristics of the Antidementia Acetylcholinesterase-Inhibiting Methanol Extracts from Umbilicaria esculenta

Lee JS, Min GH, Lee JS

To develop new antidementia nutraceuticals, a potent acetylcholinesterase (AChE)-inhibiting extract was screened from various extracts of nutritional mushrooms and lichens nutritional and its physicochemical properties were investigated. Among the several...
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The Effects of Ethanol on Cholinesterase Inactivation by Organophosphorous

Choi HC, Kim JH, Ha JH, Lee KY, Kim WJ, Woo HJ, Huh CU, Son SM, Chun EJ

  • KMID: 2320290
  • Yeungnam Univ J Med.
  • 1999 Dec;16(2):326-332.
BACKGROUND: In korea the agricultural community widely uses organophosphorous, and organophosphorous poisonings are increasing every year. We compared change in activity of acetylcholinesterase and pseudocholinesterase by organophosphorous and by the interaction...
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Pisa Syndrome in a Patient with Alzheimer's Disease and Concomitant Normal Pressure Hydrocephalus: A Case Report

Kwon OD

  • KMID: 2343315
  • J Korean Neurol Assoc.
  • 2008 Feb;26(1):73-77.
Extrapyramidal symptoms are common in patients with advanced Alzheimer's disease and have various etiologies. We report a 65-year-old man with probable Alzheimer's disease (AD) who concomitantly developed Pisa syndrome, ataxic...
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A meningomyelocele with normal intracranial signs on ultrasound and false-negative amniotic fluid alpha-fetoprotein and acetylcholinesterase

Yoon CH, Kang SK, Jin CH, Park MS, Rho JH

Neural tube defects are the major targets of prenatal diagnoses, along with Down syndrome. Prenatal diagnosis of spina bifida is possible at second trimester of gestation through alpha-fetoprotein and acetylcholinesterase...
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Acetylcholinesterase activity in the brain of wild birds in Korea—2014 to 2016

Bang JH, Ku HO, Kang HG, Kim H, Kim S, Park SW, Kim YS, Jang I, Bae YC, Woo GH, Yi H

Acetylcholinesterase (AChE) activity level can be used as a diagnostic marker for anticholinesterase pesticide poisoning. In this study, we aimed to establish a baseline level of normal brain AChE activity...
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A Case of Central Nervous System (CNS) Toxicity in Acute Organophosphate Intoxication

Lee JS, Paik JH, Yun SH, Kim JH, Han SB, Kim JS, Jung HM

  • KMID: 1482716
  • J Korean Soc Clin Toxicol.
  • 2013 Jun;11(1):31-35.
Acute organophosphate intoxication is important because of its high morbidity and mortality. The mortality is still high despite the use of atropine as specific antidotal therapy and oximes for reactivation...
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Acute Organophosphorus Pesticide Poisoning

Lee MJ, Park JS, Hong TY, Park SS, You YH

  • KMID: 2203436
  • J Korean Soc Clin Toxicol.
  • 2008 Dec;6(2):83-90.
Organophosphate (OP) pesticides are the most common source of human toxicity globally, causing high mortality and morbidity despite the availability of atropine as a specific antidote and oximes to reactivate...
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The Effects of Donepezil, an Acetylcholinesterase Inhibitor, on Impaired Learning and Memory in Rodents

Shin CY, Kim HS, Cha KH, Won DH, Lee JY, Jang SW, Sohn UD

A previous study in humans demonstrated the sustained inhibitory effects of donepezil on acetylcholinesterase (AChE) activity; however, the effective concentration of donepezil in humans and animals is unclear. This study...
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Evolutionary Patterns with Age of Acetylcholinesterase Activity of Rectal Suction Biopsies in Hirschsprung's Disease

Park WH, Choi SO, Kim SP, Chang ES, Paik TW

The acetylcholinesterase(ACHE) activity in 37 biopsies from the patients with Hirschsprung's disease was analyzed for histochemical patterns according to age, and its evolutional behavior was also assessed. The histochemical criterion...
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Extraction and Characteristics of Anti-obesity Lipase Inhibitor from Phellinus linteus

Lee JK, Jang JH, Lee JT, Lee JS

  • KMID: 2312564
  • Mycobiology.
  • 2010 Mar;38(1):52-57.
To develop a potent anti-obesity lipase inhibitor from mushroom, the lipase inhibitory activities of various mushroom extracts were determined. Methanol extracts from Phellinus linteus fruiting body exhibited the highest lipase...
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