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Effects of acarbose on the expression of obese and neuropeptide Y (NPY) genes in mice on high-carbohydrate diet

Kim J, Chung S

  • KMID: 1554059
  • Korean J Physiol Pharmacol.
  • 1999 Aug;3(4):433-438.
Two components of the neuroendocrine-hormonal response to long-term treatment of acarbose, adipose tissue-derived leptin and central neuropeptide Y (NPY), were investigated in the ICR mice on a high-carbohydrate diet. Acarbose, administered 5 or...
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Antidiabetic activity and mechanisms of acarbose in KKAy mice

Kim YL, Chung SH

  • KMID: 2285239
  • Korean J Physiol Pharmacol.
  • 2001 Apr;5(2):183-188.
To elucidate antidiabetic effect and mechanism(s) of acarbose in a polygenic spontaneous hyperglycemic and hyperinsulinemic diabetic animal model, KKAy mice, acarbose was administered orally for 4 weeks and effects on body weight, plasma...
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The Effect of Acarbose as an Adjuvant Therapy in Sulfonylurea-Treated NIDDM Patients

Lee YY, Park GS, Kim JS, Mun BS, Park DJ, Shin CS, Park KS, Kim SY, Lee HK

  • KMID: 2008332
  • J Korean Diabetes Assoc.
  • 1997 Dec;21(4):484-492.
BACKGROUND: Acarbose-an aglucosidase inhibitor-is known to have a glucose lowering effect by delaying the digestion of complex carbohydrates in the small intestine. Acarbose especially prevents the abnormally high increment of...
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A Case of Postprandial Hypotension in the Intensive Care Unit Treated With Acarbose

Choi JH, Lee HS, Lee TY, Jang E, Kang MH, Cho DK

Postprandial hypotension (PPH) has not been described as a cause of hypotension after the return of spontaneous circulation (ROSC) in the intensive care unit (ICU). A 74 year old man...
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Comparative Study about the Effects of Acarbose and Voglibose in Type 2 Diabetic Patients

Jeong IK, Chung JH, Min YK, Lee MS, Lee MK, Kim KW, Chung YE, Park JY, Hong SK, Lee KU

  • KMID: 2063387
  • J Korean Diabetes Assoc.
  • 2002 Apr;26(2):134-145.
BACKGROUND: Acarbose and voglibose are alpha-glucosidase inhibitors. Although different pharmacological effects and adverse abdominal events associated with the two drugs have been reported, no study directly compared acarbose and voglibose...
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A case of postprandial hypotension presenting with postprandial dizziness

Kim SK, Noh KH

  • KMID: 2258790
  • Korean J Med.
  • 2008 Sep;75(3):358-361.
Postprandial hypotension is an important minor clinical problem. It is a common disorder that causes unexplained dizziness, falls, lightheadedness, syncope, angina pectoris, and even transient ischemic attacks of the brain....
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Acarbose Add-on Therapy in Patients with Type 2 Diabetes Mellitus with Metformin and Sitagliptin Failure: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study

Yang HK, Lee SH, Shin J, Choi YH, Ahn YB, Lee BW, Rhee EJ, Min KW, Yoon KH

BACKGROUND: We evaluated the efficacy and safety of acarbose add-on therapy in Korean patients with type 2 diabetes mellitus (T2DM) who are inadequately controlled with metformin and sitagliptin. METHODS: A total...
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Quercetin attenuates fasting and postprandial hyperglycemia in animal models of diabetes mellitus

Kim JH, Kang MJ, Choi HN, Jeong SM, Lee YM, Kim JI

  • KMID: 2313506
  • Nutr Res Pract.
  • 2011 Apr;5(2):107-111.
The objective of this study was to investigate the hypoglycemic effects of quercetin (QE) in animal models of diabetes mellitus (DM). A starch solution (1 g/kg) with and without QE...
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Autumn olive (Elaeagnus umbellata Thunb.) berry reduces fasting and postprandial glucose levels in mice

Kim JI, Baek HJ, Han DW, Yun JA

BACKGROUND/OBJECTIVES: Fasting and postprandial hyperglycemia should be controlled to avoid complications of diabetes mellitus. This study investigated the effects of autumn olive (Elaeagnus umbellata Thunb.) berry (AOB) on fasting and...
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Short-term Therapeutic Efficacy of Different Oral Hypoglycemic Agents Combined with Once Daily Insulin Glargine in Type 2 Diabetic Subjects with Failure of Sulfonylurea and Metformin Combination

Hong SI, Kim HJ, Bae JM, Song SO, Park KS, Jeon BS, Hwang SD, Choi JY, Kim JH, Kwon HJ, Choi JS, Woo ML, Cho JH, Won YJ

Backgroud: Although the extended duration of action of insulin glargine supports a convenient once daily injection, the combination with other short acting insulins or oral hypoglycemic agents is required to...
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Postprandial Dizziness/Syncope Relieved by Alfa-Glucosidase Inhibitor: A Case Report

An H, Jeong SH, Kim HJ, Sohn EH, Lee AY, Kim JM

A 74-year-old man presented with positional vertigo and prandial dizziness and syncope. He had experienced episodes of frequent dizziness and loss of consciousness for several months. He underwent total gastrectomy...
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Comparison of Acarbose and Voglibose in Diabetes Patients Who Are Inadequately Controlled with Basal Insulin Treatment: Randomized, Parallel, Open-Label, Active-Controlled Study

Lee MY, Choi DS, Lee MK, Lee HW, Park TS, Kim DM, Chung CH, Kim DK, Kim IJ, Jang HC, Park YS, Kwon HS, Lee SH, Shin HK

We studied the efficacy and safety of acarbose in comparison with voglibose in type 2 diabetes patients whose blood glucose levels were inadequately controlled with basal insulin alone or in...
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Hepatic encephalopathy

Kim CW

  • KMID: 2256159
  • Korean J Med.
  • 2008 Jul;75(1):27-36.
Hepatic encephalopathy, one of the major complications of cirrhosis, is a neuropsychiatric syndrome caused by accumulation of toxins in the central nervous system following dysfunction in liver detoxification. Various manifestations...
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The ingredients in Saengshik, a formulated health food, inhibited the activity of alpha-amylase and alpha-glucosidase as anti-diabetic function

Kim M, Kim E, Kwak HS, Jeong Y

BACKGROUND/OBJECTIVES: We investigated total 26 ingredients of Saengshik which will be commercially produced as an anti-diabetic dietary supplement. SUBJECTS/METHODS: Thirteen vegetables, nine cereals, three legumes and one seed were extracted with...
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Hypoglycemic and antioxidant effects of Daraesoon (Actinidia arguta shoot) in animal models of diabetes mellitus

Lee AY, Kang MJ, Choe E, Kim JI

BACKGROUND/OBJECTIVES: The primary objective of the treatment of diabetes mellitus is the attainment of glycemic control. Hyperglycemia increases oxidative stress which contributes to the progression of diabetic complications. Thus, the...
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Hypoglycemic effects of Welsh onion in an animal model of diabetes mellitus

Kang MJ, Kim JH, Choi HN, Kim MJ, Han JH, Lee JH, Kim JI

  • KMID: 2313484
  • Nutr Res Pract.
  • 2010 Dec;4(6):486-491.
Tight control of blood glucose is the most important strategy for the treatment of diabetes mellitus. Here, we investigated the beneficial effects of Welsh onion on fasting and postprandial hyperglycemia....
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A case of dumping syndrome presenting as hypoglycemic shock with dramatic improvement by octreotide treatment

Hong JM, Choi SH, Rim HS, Cha BS, Lim SK, Lee HC, Huh KB

  • KMID: 1985132
  • Korean J Med.
  • 2002 Nov;63(5):567-571.
Following gastric surgery, 25~50% of patients experience dumping symptoms. Early dumping usually involves both gastro-intestinal and vasomotor complaints, while late dumping involves mainly the latter. Management is mainly achieved by...
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Comparison of antioxidant, alpha-glucosidase inhibition and anti-inflammatory activities of the leaf and root extracts of Smilax china L.

Kim KK, Kang YH, Kim DJ, Kim TW, Choe M

  • KMID: 2327113
  • J Nutr Health.
  • 2013 Aug;46(4):315-323.
This study was conducted in order to compare the biological activities of leaf and root water extracts of Smilax china L. (SC) by measuring the total polyphenol and flavonoid contents,...
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Microscopic colitis in a single center study: clinical feature & characteristics

Lee SY, Jeon SW, Chung YJ, Park YD, Yoon SJ, Park SY, Kim ES, Jung MK, Kim SK, Choi YH, Cho CM, Tak WY, Kweon YO

  • KMID: 2305865
  • Korean J Med.
  • 2008 Apr;74(4):397-402.
BACKGROUND/AIMS: Collagenous colitis (CC) and lymphocytic colitis (LC) are characterized by chronic diarrhea and normal radiologic and endoscopic findings. These are currently not uncommon entities whose incidence in increasing as...
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Lotus leaf alleviates hyperglycemia and dyslipidemia in animal model of diabetes mellitus

Kim AR, Jeong SM, Kang MJ, Jang YH, Choi HN, Kim JI

  • KMID: 2313665
  • Nutr Res Pract.
  • 2013 Jun;7(3):166-171.
The purpose of this study was to investigate the effects of lotus leaf on hyperglycemia and dyslipidemia in animal model of diabetes. Inhibitory activity of ethanol extract of lotus leaf...
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