- Long Term Safety and Efficacy of Abatacept in Patients with Rheumatoid Arthritis
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Lee CK
- KMID: 2223029
- J Rheum Dis.
- 2013 Apr;20(2):71-73.
- doi: 10.4078/jrd.2013.20.2.71
No abstract available. -
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- Long-term Safety and Efficacy of Abatacept in Koreans with Rheumatoid Arthritis
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Shim SC, Park SH, Bae SC, Choe JY, Song YW, Mitra P, Karyekar C
- KMID: 2223046
- J Rheum Dis.
- 2013 Feb;20(1):30-39.
- doi: 10.4078/jrd.2013.20.1.30
OBJECTIVE: The safety and efficacy of intravenous (IV) abatacept in patients with active RA unresponsive to methotrexate have been demonstrated in short-term (ST) studies in global populations and a ST,... -
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- A Rare Case of Overlap Syndrome with Diffuse Systemic Sclerosis, Rheumatoid Arthritis, and Cutaneous Sarcoidosis
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Ko KM, Moon SJ, Koh JH, Kim J, Min JK
- KMID: 2459454
- J Rheum Dis.
- 2019 Oct;26(4):282-285.
- doi: 10.4078/jrd.2019.26.4.282
Overlap syndrome is defined as a disease entity that satisfies the classification criteria of at least two connective tissue diseases occurring concurrently or separately in a single patient. Here, we... -
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- Risk of Herpes Zoster in Patients with Rheumatoid Arthritis Undergoing Biologic Disease-Modifying Therapy
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Kwon HM, Lee SJ, Yang JA, Choi Y, Park JK, Lee EY, Song YW, Lee EB
- KMID: 2389063
- J Rheum Dis.
- 2017 Aug;24(4):220-226.
- doi: 10.4078/jrd.2017.24.4.220
OBJECTIVE: Rheumatoid arthritis (RA) patients suffer from an increased risk of herpes zoster (HZ) partially due to immunosuppressant medications. This study investigated HZ in RA patients treated with biologic disease-modifying... -
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- Vaccination for Patients with Rheumatic Diseases in the Era of Biologics
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Han SH
- KMID: 2408927
- J Rheum Dis.
- 2018 Apr;25(2):100-107.
- doi: 10.4078/jrd.2018.25.2.100
A large proportion of patients with rheumatic disease have an immunocompromised status resulting from disease pathogenesis itself and/or several immunosuppressive drugs including biologics. These conditions are closely related to a... -
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- New drugs for Rheumatoid arthritis
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Seo YI
- KMID: 2257380
- Korean J Med.
- 2009 Jan;76(1):12-17.
Since the late 1990s, based on scientific advancement and biotechnological improvement, many effective drugs such as leflunomide and biologic agents for rheumatoid arthritis (RA) have been developed. These include TNF-alpha... -
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- Comparative Effectiveness of Biologic DMARDs in Rheumatoid Arthritis Patients with Inadequate Response to conventional DMARDs: Using a Bayesian Network Meta-analysis
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Park SK, Kim HL, Lee MY, Kim A, Lee EK
- KMID: 2226396
- Korean J Clin Pharm.
- 2015 Mar;25(1):9-17.
- doi: 10.0000/kjcp.2015.25.1.9
BACKGROUND: Biologic disease-modifying antirheumatic drugs (bDMARDs) extend the treatment choices for rheumatoid arthritis patients with insufficient response or intolerance to conventional DMARDs (cDMARDs). These agents have considerable efficacy compared with... -
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- Cost-Minimization Analysis of Biologic Disease-Modifying Antirheumatic Drugs Administered by Subcutaneous Injections in Patients with Rheumatoid Arthritis
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Park SH, Lee MY, Lee EK
- KMID: 2226432
- Korean J Clin Pharm.
- 2016 Mar;26(1):59-69.
- doi: 10.0000/kjcp.2016.26.1.59
BACKGROUND: The subcutaneous formulation of biologic disease-modifying antirheumatic drugs (DMARDs) was preferred due to favored self-administration and would be an economical treatment option for patients with rheumatoid arthritis. This study... -
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- Transaminase Changes in Korean Rheumatoid Arthritis Patients with Chronic Hepatitis C after Biologic Therapy
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Kwon HM, Shin K, Moon JY, Lee SS, Chung WT, Lee J, Lee SH, Kang SW, Suh CH, Hong SJ, Song R, Choe JY, Song YW
- KMID: 2408928
- J Rheum Dis.
- 2018 Apr;25(2):108-115.
- doi: 10.4078/jrd.2018.25.2.108
OBJECTIVE: Coexisting chronic hepatitis C can be problematic when treating rheumatoid arthritis (RA). This study examined the changes in the transaminase and viral load in hepatitis C virus (HCV)-infected RA... -
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- dNP2-ctCTLA-4 inhibits German cockroach extract-induced allergic airway inflammation and hyper-responsiveness via inhibition of Th2 responses
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Lim S, Sohn JH, Koo JH, Park JW, Choi JM
- KMID: 2389290
- Exp Mol Med.
- 2017 Aug;49(8):e362.
- doi: 10.1038/emm.2017.107
German cockroaches are major household allergens that can trigger allergic airway inflammatory diseases with sensitive T-cell responses. Although the use of immune modulatory biologics, such as antibodies, to mediate allergic... -
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- Overcome of Drug Induced Thrombotic Microangiopathy after Kidney Transplantation by Using Belatacept for Maintenance Immunosuppression
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Yun SH, Lee JH, Oh JS, Kim SM, Sin YH, Kim YJ, Kim JK
- KMID: 2202627
- J Korean Soc Transplant.
- 2016 Mar;30(1):38-43.
- doi: 10.4285/jkstn.2016.30.1.38
Thrombotic microangiopathy (TMA) is a serious complication of solid organ transplantation. Drug-induced TMA is typically caused by immunosuppressants, particularly calcineurin inhibitors. Withdrawing the causative drug can be one of the... -
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- Biologic Therapy in Rheumatoid Arthritis
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Koh EM
- KMID: 2168065
- Hanyang Med Rev.
- 2005 May;25(2):80-88.
Rheumatoid arthritis (RA) is a common autoimmune disease of unknown etiology characterized by symmetric and erosive synovitis. The course of RA is usually chronic and progressive, so it can result... -
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- Alteration of Molecules and Cytokines Related to the Activation of T Lymphocyte in Immune Tolerance Induced Mice Model
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Hur SM, Kwon CH, Joh JW, Kim SJ
- KMID: 2201804
- J Korean Soc Transplant.
- 2005 Dec;19(2):119-123.
PURPOSE: Monoclonal antibodies (mAb) specific for CD45RB as a potent tolerogenic target can prolong allograft survival in several animal models. The mechanisms of CD45RB mAb-mediated tolerance are largely unknown. Therefore,... -
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- Inhibitory effects of CTLA4-Ig fusion protein on the proliferation of T cell and the antibody production of B cell
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Jang SO, Lee SY, Hong SJ
- KMID: 2178421
- J Asthma Allergy Clin Immunol.
- 2003 Dec;23(4):818-825.
BACKGROUND: Atopic asthma is characterized by activation of Th2-type T cells in the bronchial mucosa. Several reports have suggested an important role for costimulation through the CD28/CTLA4 (cytotoxic T lymphocyte-associated... -
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- Human Cytotoxic T Lymphocyte-associated Antigen 4-immunoglobulin Fusion Protein Inhibits Airway Inflammation and Hyperresponsiveness in a Murine Model of Asthma
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- KMID: 2234531
- Korean J Asthma Allergy Clin Immunol.
- 2008 Sep;28(3):205-213.
BACKGROUND: CD4+ T helper cells which differentiate into the Th2 cells are crucial for the initiation and progression of allergic asthma. Human Cytotoxic T Lymphocyte- associated Antigen 4-immunoglobulin (CTLA4-Ig) has... -
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