- The effect of vitamine E on intestinal tumorigenesis by 1,2-dimethylhydrazine
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Lee KH, Kang DY
- KMID: 1694060
- J Korean Cancer Assoc.
- 1991 Mar;23(1):29-38.
No abstract available. -
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- Role of Protein Kinase C in Abnormal Proliferation of Vascular Endothelial Cell induced by 1,2-Dimethylhydrazine; Analysis of Isoform
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Lee J, Bae YC, Park SY, Moon JS, Nam SB
- KMID: 2203288
- J Korean Soc Plast Reconstr Surg.
- 2007 Jan;34(1):8-12.
PURPOSE: Protein tyrosine kinase(PTK), protein kinase C(PKC), oxidase, as a mediator, have been known to take a role in signal transduction pathway of angiogenesis. The authors confirmed that PKC is... -
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- Inhibition by Ginseng of Colon Carcinogenesis in Rats
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Fukushima , Wanibuchi , Li W
- KMID: 1721179
- J Korean Med Sci.
- 2001 Dec;16(Suppl):S75-S80.
- doi: 10.3346/jkms.2001.16.S.S75
The inhibitory effects of ginseng on the development of 1,2-dimethylhydrazine (DMH)-induced aberrant crypt foci (ACF) in the colon were investigated in rats. Male, 6-week-old rats were injected with DMH once... -
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- The Light and Electron Microscopic Study of Mucosal Changes of Colonic Lesion Induced by 1,2-Demethylhydrazined 2HCl in the Rats
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Hong KS, Han WS, Kim OK
- KMID: 1965709
- Ewha Med J.
- 1987 Mar;10(1):5-19.
- doi: 10.12771/emj.1987.10.1.5
The fact that the administration of 1,2-dimethylhydrazine 2Hcl(DMH) to rats by weekly subcutaneous injections causes the development of epithelial tumors of the large intestine has been known. But the axact... -
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- Sequential Changes in Aberrant Crypt Foci and Lectin Expression in the Early and Late Stages of DMH-Induced Colon Carcinogenesis in Rats
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Won HS, Maeng LS, Chae HS, Kim HK, Cho YS, Kang JH, Jang HS, Ryu MR
- KMID: 2284269
- Gut Liver.
- 2012 Apr;6(2):229-234.
BACKGROUND/AIMS: The purpose of this study was to investigate the malignant potential of aberrant crypt foci (ACF) by measuring the multiplicity of crypts and lectin expression in the early and... -
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- Effect of Dietary CLA Isomers on Apoptosis and Cell Proliferation in Colonic Mucosa of DMH-Treated Rats
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Park HS, Kwon PS, Park JH, Ha YL
- KMID: 2269681
- Korean J Nutr.
- 2003 Sep;36(7):661-666.
The study was designed to compare the anti-carcinogenic effect of conjugated linoleic acid (CLA) isomers on colon carcinogenesis in 1,2-dimethylhydrazine (DMH)-treated rats by determining the levels of apoptosis, cell proliferation,... -
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- Effect of Dietary Conjugated Linoleic Acid (CLA) Isomers on Tumor Incidence and the Protein Expression of Cyclooxygenase-2 and Protein Kinase C in Colonic Mucosa of DMH-Treated Rats
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Park HS, Chun CS, Yoon JH
- KMID: 2269800
- Korean J Nutr.
- 2004 Nov;37(9):763-770.
This study was designed to compare the anti-carcinogenic effect of conjugated linoleic acid isomers on tumor incidence, cell proliferation and the levels of thromboxane (TX)B2, prostaglandin (PG)E2 and 1,2-diacylglycerol (DAG),... -
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- Overexpression of cyclin D1 and cyclin E in 1,2-dimethylhydrazine dihydrochloride-induced rat colon carcinogenesis
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Hur K, Kim JR, Yoon BI, Lee JK, Choi JH, Oh GT, Kim DY
- KMID: 1094650
- J Vet Sci.
- 2000 Dec;1(2):121-126.
Deregulation of G1 cyclins has been reported in several human and rodent tumors including colon cancer. To investigate the expression pattern of G1 cyclins in 1,2- dimethyl-hydrazine dihydrochloride (DMH)-induced rat... -
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