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Islet Transplantation and Regeneration for Treatment of Diabetes

Yamada Y

Islet transplantation has the potential to restore normoglycemia and prevent the development of diabetic complications such as retinopathy, nephropathy and neuropathy, and could therefore ve a valuable treatment for diabetic...
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Relationship between Utrophin and Regenerating Muscle Fibers in Duchenne Muscular Dystrophy

Shim JY, Kim TS

Duchenne muscular dystrophy (DMD) is a dystrophinopathy, and its associated gene is located on Xp21. Moreover, utrophin, a recently identified structural homologue of dystrophin is reported to be up-regulated in...
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Intramyocardial Transplantation of Circulating CD34+ cells: Source of Stem Cells for Myocardial Regeneration

Kim YH

This study was designed to investigate the increase in the number of circulating CD34+ cells after acute myocardial infarction (MI) and the differentiation of these cells to cardiomyocytes after transplantation...
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Expression of 4-1BB and 4-1BBL in thymocytes during thymus regeneration

Kim YM, Kim HK, Kim HJ, Lee HW, Ju SA, Choi BK, Kwon BS, Kim BS, Kim JB, Lim YT, Yoon S

4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily, is a major costimulatory receptor that is rapidly expressed on the surface of CD4+ and CD8+ T cells after...
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Vitamin D3 up-regulated protein 1 controls the priming phase of liver regeneration

Kwon HJ, Hong SK, Yoon WK, Nam KH, Choi IP, Kim DY, Kim HC, Won YS

Vitamin D3 up-regulated protein 1 (VDUP1) is a potent growth suppressor that inhibits tumor cell proliferation and cell cycle progression when overexpressed. In a previous study, we showed that VDUP1...
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Strategies for ensuring that regenerative cardiomyocytes function properly and in cooperation with the host myocardium

Hattori F, Fukuda K

In developed countries, in which people have nutrient-rich diets, convenient environments, and access to numerous medications, the disease paradigm has changed. Nowadays, heart failure is one of the major causes...
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Clinical applications of mesenchymal stem cells

Kim N, Cho SG

Mesenchymal stem cells (MSCs) are self-renewing, multipotent progenitor cells with multilineage potential to differentiate into cell types of mesodermal origin, such as adipocytes, osteocytes, and chondrocytes. In addition, MSCs can...
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Human salivary gland stem cells ameliorate hyposalivation of radiation-damaged rat salivary glands

Jeong J, Baek H, Kim YJ, Choi Y, Lee H, Lee E, Kim ES, Hah JH, Kwon TK, Choi IJ, Kwon H

  • KMID: 2154277
  • Exp Mol Med.
  • 2013 Nov;45(11):e58.
Salivary function in mammals may be defective for various reasons, such as aging, Sjogren's syndrome or radiation therapy in head and neck cancer patients. Recently, tissue-specific stem cell therapy has...
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