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Proteomic Approach in Gastrointestinal and Liver Research

Yeo M, Cho SW, Hahm KB

  • KMID: 772691
  • Korean J Gastroenterol.
  • 2004 Nov;44(5):239-245.
In the post-genomic era, the focus of research is now moving to functional genomics employing the information on predicted gene products provided by genome sequencing. Proteomics, the global analysis of...
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The Path to Clinical Proteomics Research: Integration of Proteomics, Genomics, Clinical Laboratory and Regulatory Science

Boja ES, Rodriguez

Better biomarkers are urgently needed to cancer detection, diagnosis, and prognosis. While the genomics community is making significant advances in understanding the molecular basis of disease, proteomics will delineate the...
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Proteomic applications of surface plasmon resonance biosensors: analysis of protein arrays

Yuk JS, Ha KS

  • KMID: 1033095
  • Exp Mol Med.
  • 2005 Feb;37(1):1-10.
Proteomics is one of the most important issues in the post-genomic area, because it can greatly contribute to identifying protein biomarkers for disease diagnosis and drug screening. Protein array is...
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Proteomics Analysis for Helicobacter pylori-infected Gastric Mucosa

Kang HS, Hong SN, Park HR, Kwon MJ, Lee JH, Kim JJ

BACKGROUND/AIMS: Helicobacter pylori infection is linked to the development of gastric cancer. H. pylori-associated gastric inflammation is considered to be the first important step in the histogenesis of such neoplasia....
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Identification of 10 Candidate Biomarkers Distinguishing Tuberculous and Malignant Pleural Fluid by Proteomic Methods

Lee CY, Hong JY, Lee MG, Suh IB

PURPOSE: Pleural effusion, an accumulation of fluid in the pleural space, usually occurs in patients when the rate of fluid formation exceeds the rate of fluid removal. The differential diagnosis...
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Proteomic Profiling of Serum from Patients with Tuberculosis

Song SH, Han M, Choi YS, Dan KS, Yang MG, Song J, Park SS, Lee JH

BACKGROUND: Effective treatment and monitoring of tuberculosis (TB) requires biomarkers that can be easily evaluated in blood samples. The aim of this study was to analyze the serum proteome of...
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Proteomic Analysis of Toxoplasma gondii KI-1 Tachyzoites

Choi SH, Kim TY, Park SG, Cha GH, Shin DW, Chai JY, Lee YH

We studied on the proteomic characteristics of Toxoplasma gondii KI-1 tachyzoites which were originally isolated from a Korean patient, and compared with those of the well-known virulent RH strain using...
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Protein Profile Changes in Platelet Concentrates According to Storage and Leukoreduction- Analysis Using Proteomics Technology

Ryu SW, Suh IB, Cho Y

BACKGROUND: Knowing how the protein profile of platelet products changes with storage or leukoreduction may give us greater insight into cell physiology and the cause of transfusion reactions other than...
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Functional proteomics, human genetics and cancer biology of GIPC family members

Katoh M

  • KMID: 2154245
  • Exp Mol Med.
  • 2013 Jun;45(6):e26.
GIPC1, GIPC2 and GIPC3 consist of GIPC homology 1 (GH1) domain, PDZ domain and GH2 domain. The regions around the GH1 and GH2 domains of GIPC1 are involved in dimerization...
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Comparative profiling of plasma proteome from breast cancer patients reveals thrombospondin-1 and BRWD3 as serological biomarkers

Suh EJ, Kabir MH, Kang UB, Lee JW, Yu J, Noh DY, Lee C

Breast cancer is the most common cancer in women worldwide. It is necessary to identify biomarkers for early detection, to make accurate prognoses, and to monitor for any recurrence of...
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Proteomic differences with and without ozone-exposure in a smoking-induced emphysema lung model

Uh ST, Koo SM, Jang AS, Park SW, Choi JS, Kim YH, Park CS

BACKGROUND/AIMS: Acute exacerbations in chronic obstructive pulmonary disease may be related to air pollution, of which ozone is an important constituent. In this study, we investigated the protein profiles associated...
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Comparative proteomic analysis of proteins expression changes in the mammary tissue of cows infected with Escherichia coli mastitis

Zhao XW, Yang YX, Huang DW, Cheng GL, Zhao HL

Cows infected with Escherichia (E.) coli usually experience severe clinical symptoms, including damage to mammary tissues, reduced milk yield, and altered milk composition. In order to investigate the host response...
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Proteomic Screening of Antigenic Proteins from the Hard Tick, Haemaphysalis longicornis (Acari: Ixodidae)

Kim YH, slam MS, You MJ

Proteomic tools allow large-scale, high-throughput analyses for the detection, identification, and functional investigation of proteome. For detection of antigens from Haemaphysalis longicornis, 1-dimensional electrophoresis (1-DE) quantitative immunoblotting technique combined with...
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Candidates for Tumor Markers of Cervical Cancer Discovered by Proteomic Analysis

Song JY, Bae HS, Koo DH, Lee JK, Jung HH, Lee KW, Lee NW

Cervical cancer is the second most common gynecological cancer among Korean women. While nationwide screening program has developed, the pathogenesis of cervical cancer is unknown. The aim of this study...
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