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Brief Introduction of Panax ginseng C.A. Meyer

Yun TK

For many many thousand years, mankind has been using various plants as nutrient, beverage, cosmetics, dye and medicine to maintain health and to improve quality of life. In Aisa, particularly,...
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Molecular Mechanisms Underlying Anti-Tumor Promoting Activities of Heat-Processed Panax ginseng C.A. Meyer

Surh YJ, Na HK, Lee JY, Keum YS

Recently, there have been considerable efforts to search for naturally occurring substances that can inhibit, reverse, or retard the multi-stage carcinogenesis. A wide array of phenolic substances derived from edible...
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Anticarcinogenic Effect of Panax ginseng C.A. Meyer and Identification of Active Compounds

Yun TK, Lee YS, Lee YH, Kim SI, Yun HY

The failure to improve the five-year survival rate of cancer patients, from one in three in the 1960s to one in two in the 1970s, stimulated awareness of the importance...
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Anticarcinogenic Effect of Red Ginseng on the Development of Liver Cancer Induced by Diethylnitrosamine in Rats

Wu XG, Zhu DH, Li X

Anticarcinogenic effect of red ginseng (Panax ginseng C.A. Meyer cultivated in JiLin, China) on the development of liver cancer induced by diethylnitrosamine (DEN) in rats was studied, especially in preventive...
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Epidemiological Study on Cancer Prevention by Ginseng: Are All Kinds of Cancers Preventable by Ginseng?

Yun TK, Choi SY, Yun HY

In the light of experimental results, two case-control studies and one cohort study in a population of ginseng cultivation area were conducted to confirm whether ginseng has any anticarcinogenic effect...
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Chemistry and Cancer Preventing Activities of Ginseng Saponins and Some Related Triterpenoid Compounds

Shibata S

More than 25 dammarane-type tetracyclic triterpenoid saponins have been isolated from ginseng, the root and rhizome of Panax ginseng C.A. Meyer (Araliaceae). The genuine sapogenins of those saponins, 20(S)-protopanaxa-diol and...
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The Perception of Ginseng in England and America, 1600-1800

Sul H

This paper aims to redress serious imbalances in the research on ginseng. Most accounts of ginseng treat it as an exclusively East Asian commodity, and are dominated by the natural...
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Mast Cell Degranulation with Special Reference to the Effect of a Saponin Extract of Ginseng upon the Mesenteric Mast Cell of Albino Rats

Pak SY, Song CS, Choi KD

Water extract of dried ginseng, which is known as a histamine liberator and induces degranulation and disruption of mesenteric mast cells, is thought to contain many different chemical factors. The...
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A Phase Contrast Microscopic Study on the Induction of Cellular Deformation in Mast Cells

Choi KD, Oh YK, Park DU, Rhim KS, Cho TH

The influence of colchicine, colcemid, ginseng-alcohol extract, saponin, garlic alcohol-ether extract, and X-irradiation on free floating peritoneal mast cells were studied in rats by means of a phase contrast microscope....
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Study on Chemoprevention of Hepatocellular Carcinoma by Ginseng: An Introduction to the Protocol

The Ginseng-HCC Chemopreventive Study Osaka Group

In patients with chronic hepatitis C virus disease, there is a high incidence of development of hepatocedllular carcinaoma (HCC) in the process of transition from chronic hepatitis to hepatic cirrhosis....
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Inhibition by Ginseng of Colon Carcinogenesis in Rats

Fukushima , Wanibuchi , Li W

The inhibitory effects of ginseng on the development of 1,2-dimethylhydrazine (DMH)-induced aberrant crypt foci (ACF) in the colon were investigated in rats. Male, 6-week-old rats were injected with DMH once...
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The Effects of Korean Red Ginseng (Ginseng Radix Rubra) on Liver Regeneration after Partial Hepatectomy in Dogs

Kwon YS, Jang KH, Jang IH

  • KMID: 1099826
  • J Vet Sci.
  • 2003 Apr;4(1):83-92.
We investigated the effects of the oral administration of Korean red ginseng (KRG) on morphologic change and function of liver in dogs. Fifteen adult mongrel dogs (n=15) were divided into...
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A Crisis of Ginseng Capital and the Countermeasures of the Ginseng-cultivating People during Daehan Empire

Yang JP

  • KMID: 1070696
  • Korean J Med Hist.
  • 2009 Dec;18(2):133-155.
This thesis examines a crisis of ginseng capital and the source of crisis during Daehan empire. After the China-Japan war of 1894, the Japanese merchants actively engaged in taking over...
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A Study on the Origins of 'Korean Ginseng'

Yang JP, Yeo IS

  • KMID: 877201
  • Korean J Med Hist.
  • 2004 Jun;13(1):1-19.
Generally the originating area of ginseng is known to be in Shangdang, China. The originating time, which has been estimated according to textual and archeological outcomes, is known to be...
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Colon Cancer Chemoprevention With Ginseng and Other Botanicals

Wargovich

Colorectal cancer is becoming increasingly common in Asian countries and still remains the second leading cause of cancer deaths in the United States. Efforts to prevent colon cancer have targeted...
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Ginseng Total Saponin Improves Podocyte Hyperpermeability Induced by High Glucose and Advanced Glycosylation Endproducts

Ha TS, Choi JY, Park HY, Lee JS

Early diabetic nephropathy is characterized by glomerular hyperpermeability as a result of impaired glomerular filtration structure caused by hyperglycemia, glycated proteins or irreversible advanced glycosylation endproducts (AGE). To investigate the...
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Cancer Chemoprevention by Ginseng in Mouse Liver and Other Organs

Nishino H, Tokuda H, Ii T, Takemura M, Kuchide M, Kanazawa M, Mou XY, Bu P, Takayasu J, Onozuka M, Masuda M, Satomi Y, Konoshima , Kishi N, Baba M, Okada Y, Okuyama T

Oral administration of red ginseng extracts (1% in diet for 40 weeks) resulted in the significant suppression of spontaneous liver tumor formation in C3H/He male mice. Average number of tumors...
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American Ginseng Transcriptionally Activates p21 mRNA in Breast Cancer Cell Lines

Duda RB, Kang SS, Archer SY, Meng S, Hodin RA

American ginseng (AG) has been demonstrated to inhibit breast cancer cell growth in vitro. p21 protein, a universal cell cycle inhibitor, binds cyclin-CDK complexes, an important mechanism in cell cycle...
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